The effect of avermectins on feeding, salivary fluid secretion, and fecundity in some ixodid ticks

1986 ◽  
Vol 2 (1) ◽  
pp. 1-18 ◽  
Author(s):  
W. Reuben Kaufman ◽  
Sandra G. Ungarian ◽  
Alexandra E. Noga
Keyword(s):  
Fluid Secretion ◽  
Ixodid Ticks

CYCLIC NUCLEOTIDES, CALCIUM AND SALIVARY FLUID SECRETION IN IXODID TICKS

1979 ◽  
pp. 365-373 ◽  
Author(s):  
J.R. Sauer ◽  
G.R. Needham ◽  
H.L. McMullen ◽  
R.D. Morrison
Keyword(s):  
Cyclic Nucleotides ◽  
Fluid Secretion ◽  
Ixodid Ticks

The influence of various factors on fluid secretion by in vitro salivary glands of ixodid Ticks

1976 ◽  
Vol 64 (3) ◽  
pp. 727-742
Author(s):  
W. Kaufman
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Culture Medium ◽  
Dry Weight ◽  
Fluid Secretion ◽  
Ixodid Tick ◽  
Ixodid Ticks ◽  
Mammalian Tissue ◽  
Stimulating Factor

1. Salivary glands of the female ixodid tick, Dermacentor andersoni, secrete fluid in vitro when bathed in a slightly modified version of the mammalian tissue culture medium ‘TC 199′. 2. Rate of salivation in vitro increases with progression of feeding, but there is no comparable increase in dry weight of the salivary glands during the early phase of engorgement. Engorged ticks secreted at only 25% the rate of 90–250 mg ticks, indicating that salivary gland degeneration has already begun in the very early post-engorgement stage. 3. A salivary gland stimulating factor can be detected in the nervous system but not in other tissues. 4. Male salivary glands secrete at only 1/20th the rate of female glands. Thus males probably do not use their salivary glands as osmoregulatory organs. 5. From the uniform lack of response to ACh and uniform response to DA in 7 ixodid tick species, it is suggested that the control of salivation is similar throughout the ixodid family.

Neural pathways mediating salivary fluid secretion in the ixodid tick Amblyomma hebraeum

1983 ◽  
Vol 61 (9) ◽  
pp. 1976-1980 ◽  
Author(s):  
W. R. Kaufman ◽  
R. A. Harris
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Fluid Secretion ◽  
Ixodid Tick ◽  
Ixodid Ticks ◽  
Sensory Receptor ◽  
Neural Pathways ◽  
Amblyomma Hebraeum ◽  
The Central Nervous System ◽  
Cholinomimetic Drugs

In ixodid ticks, the salivary glands are innervated by at least two nerves: one arising from the so called lateral plexus (SGNlp) and one arising as a branch of the palpal nerve (SGNpn). The injection of cholinomimetic drugs or large volumes of isosmotic saline into the haemocoel is known to stimulate salivary fluid secretion. The object of this study was to determine which nerves mediate the latter responses. We challenged ticks with either carbachol or isosmotic saline after cutting various nerves bilaterally. Cutting the SGNlp attenuated both carbachol-induced and saline-induced secretion. Cutting the opisthosomal nerves attenuated only saline-induced secretion. Cutting the SGNpn appeared to inhibit salivation in a nonspecific manner. The data indicate that saline-induced salivation is mediated by a sensory receptor located in the opisthosoma, whereas carbachol exerts its effect either in the central nervous system or via a sensory receptor located in the cephalothorax.

Potentiation of salivary fluid secretion in ixodid ticks: a new receptor system for γ-aminobutyric acid

1986 ◽  
Vol 64 (8) ◽  
pp. 1119-1126 ◽  
Author(s):  
Paul J. Lindsay ◽  
W. Reuben Kaufman
Keyword(s):  
Salivary Glands ◽  
Fluid Secretion ◽  
Recognition Site ◽  
Ixodid Ticks ◽  
Aminobutyric Acid ◽  
Intrinsic Activity ◽  
Receptor System ◽  
Gaba Antagonists ◽  
Tick Salivary Glands

γ-Aminobutyric acid (GABA), having minimal intrinsic activity, potentiates dopamine-induced fluid secretion in salivary glands of female ixodid ticks. Because the effect of GABA was similar to that of spiperone, we tested whether these two drugs act at a common recognition site. Potentiation was not augmented when salivary glands were exposed to supramaximal concentrations of spiperone (1 μM) plus GABA (100 μM). (±)-Sulpiride (100 μM), a spiperone antagonist in this system, also blocked GABA-induced potentiation. Picrotoxin (100 μM) and (−)-bicuculline (100 μM), two GABA antagonists, blocked GABA-induced and spiperone-induced potentiation. Inhibition of GABA by picrotoxin and (−)-bicuculline was noncompetitive. Muscimol (an agonist at GABAA receptors) also potentiated dopamine-induced secretion. Baclofen (an agonist at GABAB receptors) did not elicit potentiation. We suggest that GABA may function as a neuromodulator for dopamine-induced fluid secretion in tick salivary glands.

Ethanol potentiales secretin-stimulated fluid secretion in interlobular ducts isolated from guinea-pig pancreas

2001 ◽  
Vol 120 (5) ◽  
pp. A337-A337
Author(s):  
A YAMAMOTO ◽  
S NARUSE ◽  
M KITAGAWA ◽  
H ISHIGURO ◽  
A SUZUKI ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Fluid Secretion

The GLP-1R agonist exendin-4 reduces cerebrospinal fluid secretion and intracranial pressure

2017 ◽  
Author(s):  
Hannah Botfield ◽  
Maria Uldall ◽  
Connar Westgate ◽  
James Mitchell ◽  
Snorre Hagen ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Pressure ◽  
Fluid Secretion ◽  
Cerebrospinal Fluid Secretion
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