Steroid glycosides of the seeds ofNicotiana tabacum. II. The structures of nicotianosides C and F

1996 ◽  
Vol 31 (3) ◽  
pp. 332-335 ◽  
Author(s):  
S. A. Shvets ◽  
P. K. Kintya ◽  
O. N. Gutsu ◽  
V. I. Grishkovets
Keyword(s):  
Ofnicotiana Tabacum ◽  
Steroid Glycosides

Steroid glycosides ofNicotiana tabacum seeds I. The structures of nicotianosides A, B, and E

1994 ◽  
Vol 30 (6) ◽  
pp. 684-688 ◽  
Author(s):  
S. A. Shvets ◽  
P. K. Kintya ◽  
O. N. Gutsu
Keyword(s):  
Ofnicotiana Tabacum ◽  
Steroid Glycosides

scholarly journals Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity

Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 136
Author(s):  
Silvie Rimpelová ◽  
Tomáš Zimmermann ◽  
Pavel B. Drašar ◽  
Bohumil Dolenský ◽  
Jiří Bejček ◽  
...  
Keyword(s):  
Drug Repositioning ◽  
Biological Activities ◽  
Cancer Therapeutics ◽  
Structural Identification ◽  
Induce Cell Cycle Arrest ◽  
Cycle Arrest ◽  
Steroid Glycosides ◽  
In Silico Modeling ◽  
M Phase ◽  
Atpase Inhibition

Cardiac glycosides (CGs) represent a group of sundry compounds of natural origin. Most CGs are potent inhibitors of Na+/K+-ATPase, and some are routinely utilized in the treatment of various cardiac conditions. Biological activities of other lesser known CGs have not been fully explored yet. Interestingly, the anticancer potential of some CGs was revealed and thereby, some of these compounds are now being evaluated for drug repositioning. However, high systemic toxicity and low cancer cell selectivity of the clinically used CGs have severely limited their utilization in cancer treatment so far. Therefore, in this study, we have focused on two poorly described CGs: hyrcanoside and deglucohyrcanoside. We elaborated on their isolation, structural identification, and cytotoxicity evaluation in a panel of cancerous and noncancerous cell lines, and on their potential to induce cell cycle arrest in the G2/M phase. The activity of hyrcanoside and deglucohyrcanoside was compared to three other CGs: ouabain, digitoxin, and cymarin. Furthermore, by in silico modeling, interaction of these CGs with Na+/K+-ATPase was also studied. Hopefully, these compounds could serve not only as a research tool for Na+/K+-ATPase inhibition, but also as novel cancer therapeutics.

Steroid glycosides of the roots ofCapsicum annuum. II. The structure of the capsicosides

1987 ◽  
Vol 23 (2) ◽  
pp. 202-205 ◽  
Author(s):  
E. V. Gutsu ◽  
P. K. Kintya ◽  
G. V. Lazur'evskii
Keyword(s):  
Steroid Glycosides

Expression of viral capsid protein antigen against Epstein-Barr virus in plastids ofNicotiana tabacum cv. SR1

2006 ◽  
Vol 94 (6) ◽  
pp. 1129-1137 ◽  
Author(s):  
Maggie Y.T. Lee ◽  
Yuanxiang Zhou ◽  
Raymond W.M. Lung ◽  
Mee-Len Chye ◽  
Wing-Kin Yip ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Epstein Barr Virus ◽  
Protein Antigen ◽  
Viral Capsid ◽  
Viral Capsid Protein ◽  
Barr Virus ◽  
Ofnicotiana Tabacum ◽  
Epstein Barr

scholarly journals Zebrafish Bioassay-Guided Microfractionation Identifies Anticonvulsant Steroid Glycosides from the Philippine Medicinal PlantSolanum torvum

2014 ◽  
Vol 5 (10) ◽  
pp. 993-1004 ◽  
Author(s):  
Soura Challal ◽  
Olivia E. M. Buenafe ◽  
Emerson F. Queiroz ◽  
Snezana Maljevic ◽  
Laurence Marcourt ◽  
...  
Keyword(s):  
Steroid Glycosides

Microtubular Motors in the Pollen Tube ofNicotiana tabacum

1992 ◽  
pp. 218-223
Author(s):  
Giampiero Cai ◽  
Alessandro Bartalesi ◽  
Alessandra Moscatelli ◽  
Cecilia Del Casino ◽  
Antonio Tiezzi ◽  
...  
Keyword(s):  
Pollen Tube ◽  
Ofnicotiana Tabacum
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