Effect of varying doses of chenodeoxycholic acid on bile lipid and biliary bile acid composition in gallstone patients: A dose-response study

1977 ◽  
Vol 22 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Johnson L. Thistle ◽  
Alan F. Hofmann ◽  
Paulina Y. S. Yu ◽  
Beverly Ott
Keyword(s):  
Bile Acid ◽  
Acid Composition ◽  
Chenodeoxycholic Acid ◽  
Dose Response ◽  
Biliary Bile Acid ◽  
Dose Response Study

scholarly journals Chenodeoxycholic Acid Administration Monitored by Serum Bile Acid Profiles: A Dose-Response Study

1983 ◽  
Vol 20 (6) ◽  
pp. 336-340 ◽  
Author(s):  
Malcolm J Whiting ◽  
Roger H L Down ◽  
James Mck Watts
Keyword(s):  
Bile Acid ◽  
Acid Composition ◽  
Chenodeoxycholic Acid ◽  
State Level ◽  
Serum Bile Acid ◽  
Bile Acid Profiles ◽  
Induced Changes ◽  
Dose Response Study ◽  
Acid Administration ◽  
Different Doses

Serum bile acid analysis was used to monitor the bile acid composition of bile in 16 healthy male volunteers before and during the oral administration of different doses of the gallstone-dissolving bile acid, chenodeoxycholic acid. Daily chenodeoxycholic acid ingestion increased the percentage of this bile acid in bile to a new steady-state level after two to three weeks. Doses of 125, 250, 500, and 750 mg/day significantly increased the proportion of chenodeoxycholic acid in bile from 41% to 55, 61, 78, and 79 %, respectively, during the fourth week of ingestion. The results indicate that useful information concerning chenodeoxycholic acid-induced changes in the bile acid composition of bile can be obtained solely by serum bile acid analysis, and bile collection by duodenal intubation can be avoided.

scholarly journals Metabolism of sulfonate analogs of ursodeoxycholic acid and their effects on biliary bile acid composition in hamsters.

1993 ◽  
Vol 34 (3) ◽  
pp. 429-435
Author(s):  
T Mikami ◽  
K Kihira ◽  
S Ikawa ◽  
M Yoshii ◽  
S Miki ◽  
...  
Keyword(s):  
Bile Acid ◽  
Ursodeoxycholic Acid ◽  
Acid Composition ◽  
Biliary Bile Acid

scholarly journals Biliary Bile Acid Composition of the Human Fetus in Early Gestation

1987 ◽  
Vol 21 (2) ◽  
pp. 197-200 ◽  
Author(s):  
C Colombo ◽  
G Zuliani ◽  
M Ronchi ◽  
J Breidenstein ◽  
K D R Setchel
Keyword(s):  
Bile Acid ◽  
Acid Composition ◽  
Human Fetus ◽  
Early Gestation ◽  
Biliary Bile Acid

BILIARY BILE ACID COMPOSITION OF THE PHYSETERIDAE (SPERM WHALES)

1993 ◽  
Vol 9 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Lee R. Hagey ◽  
Daniel Odell ◽  
Steven S. Rossi ◽  
Diane L. Crombie ◽  
Alan F. Hofmann
Keyword(s):  
Bile Acid ◽  
Acid Composition ◽  
Sperm Whales ◽  
Biliary Bile Acid

scholarly journals The effect of ursodeoxycholic acid on biliary bile acid composition in patients with cholesterol gallstone.

1982 ◽  
Vol 136 (3) ◽  
pp. 235-249 ◽  
Author(s):  
YOSHIHIKO KANAZAWA ◽  
MASARU KOIZUMI ◽  
HIDETOSHI HIRAKAWA ◽  
KATSUHIRO ENDO ◽  
SHIN YOSHIDA ◽  
...  
Keyword(s):  
Bile Acid ◽  
Ursodeoxycholic Acid ◽  
Acid Composition ◽  
Cholesterol Gallstone ◽  
Biliary Bile Acid
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