Effects of age and chronic renal failure on the urinary excretion kinetics of famotidine in man

1988 ◽  
Vol 34 (1) ◽  
pp. 41-46 ◽  
Author(s):  
J. H. Lin ◽  
A. N. Chremos ◽  
K. C. Yeh ◽  
J. Antonello ◽  
G. A. Hessey
2021 ◽  
Vol 343 ◽  
pp. 11-20
Author(s):  
Benedikt Ringbeck ◽  
Daniel Bury ◽  
Alexandra Gotthardt ◽  
Heiko Hayen ◽  
Rainer Otter ◽  
...  

2016 ◽  
Vol 90 (7) ◽  
pp. 1659-1667 ◽  
Author(s):  
Frederik Lessmann ◽  
André Schütze ◽  
Tobias Weiss ◽  
Angelika Langsch ◽  
Rainer Otter ◽  
...  

Author(s):  
Benedikt Ringbeck ◽  
Vladimir N. Belov ◽  
Christoph Schmidtkunz ◽  
Katja Küpper ◽  
Wolfgang Gries ◽  
...  

1993 ◽  
Vol 265 (2) ◽  
pp. E230-E235 ◽  
Author(s):  
D. Reaich ◽  
S. M. Channon ◽  
C. M. Scrimgeour ◽  
S. E. Daley ◽  
R. Wilkinson ◽  
...  

The effect of correction of acidosis in chronic renal failure (CRF) was determined from the kinetics of infused L-[1-13C]leucine. Nine CRF patients were studied before (acid) and after two 4-wk treatment periods of sodium bicarbonate (NaHCO3) and sodium chloride (NaCl) (pH: acid 7.31 +/- 0.01, NaHCO3 7.38 +/- 0.01, NaCl 7.30 +/- 0.01). Leucine appearance from body protein (PD), leucine disappearance into body protein (PS) and leucine oxidation (O) decreased significantly with correction of acidosis (PD: acid 122.4 +/- 6.1, NaHCO3 88.3 +/- 6.9, NaCl 116.2 +/- 9.1 mumol.kg-1.h-1, acid vs. NaHCO3 P < 0.01, NaHCO3 vs. NaCl P < 0.01, acid vs. NaCl NS; PS: acid 109.4 +/- 5.6, NaHCO3 79.0 +/- 6.3, NaCl 101.3 +/- 7.7 mumol.kg-1.h-1, acid vs. NaHCO3 P < 0.01, NaHCO3 vs. NaCl P < 0.01, acid vs. NaCl NS; O: acid 13.0 +/- 1.2, NaHCO3 9.2 +/- 0.9, NaCl 15.0 +/- 1.9 mumol.kg-1.h-1, acid vs. NaHCO3 P < 0.05, NaHCO3 vs. NaCl P < 0.01, acid vs. NaCl NS). There were no significant changes in plasma amino acid concentrations. These results confirm that correction of acidosis in chronic renal failure removes a potential catabolic factor.


Nephron ◽  
1998 ◽  
Vol 78 (3) ◽  
pp. 352-353 ◽  
Author(s):  
B. Di Iorio ◽  
A. Bruno ◽  
V. Terracciano ◽  
C. Altieri ◽  
D. Papaleo ◽  
...  

Hypertension ◽  
1981 ◽  
Vol 3 (4) ◽  
pp. 456-459 ◽  
Author(s):  
K Onoyama ◽  
H Hirakata ◽  
K Iseki ◽  
S Fujimi ◽  
T Omae ◽  
...  

Author(s):  
Markus Stoeckelhuber ◽  
Max Scherer ◽  
Oliver Peschel ◽  
Edgar Leibold ◽  
Franz Bracher ◽  
...  

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