Developmental changes of blood group A-active glycosphingolipids with type 1 and type 2 chains in rat small intestine

1987 ◽  
Vol 4 (1) ◽  
pp. 59-71 ◽  
Author(s):  
Daniele Bouhours ◽  
G�ran Larson ◽  
Jean-Francois Bouhours ◽  
Arne Lundblad ◽  
Gunnar C Hansson
Keyword(s):  
Small Intestine ◽  
Blood Group ◽  
Developmental Changes ◽  
Rat Small Intestine ◽  
Blood Group A ◽  
Group A

Use of Synthetic H Disaccharides as Acceptors for Detecting Activities of UDP-GalNAc:Fuc α1-->2Galβ-R α1-->3-N-Acetylgalactosaminyltransferase in Plasma Samples from Blood Group A Subgroups

1992 ◽  
Vol 38 (12) ◽  
pp. 2392-2395 ◽  
Author(s):  
S Yazawa ◽  
A Takeya ◽  
O Hosomi ◽  
T Nakajima ◽  
N Shimoda ◽  
...  
Keyword(s):  
Human Plasma ◽  
Blood Group ◽  
Enzyme Activities ◽  
Enzyme Concentration ◽  
Plasma Samples ◽  
Blood Group A ◽  
Significant Difference ◽  
Group A

Abstract Concentrations of blood group A-specified alpha(1-->3)-N-acetylgalactosaminyltransferase (A enzyme) were measured in human plasma of blood groups A1, A2, and A3 by using chemically synthesized H disaccharides and H type 1 and type 2 trisaccharides attached to hydrophobic aglycones as acceptors. When the trisaccharides were used as acceptors, enzyme activities were reduced in samples from A2 and A3. However, the H disaccharides were shown to be good acceptors even for enzymes from A2 and A3, and no significant difference in enzyme concentration was detected in any of the plasma tested.

Monoclonal antibodies defining blood group A variants with difucosyl type 1 chain (ALeb) and difucosyl type 2 chain (ALey)

Biochemistry ◽  
1985 ◽  
Vol 24 (22) ◽  
pp. 6190-6194 ◽  
Author(s):  
Henrik Clausen ◽  
John M. McKibbin ◽  
Senitiroh Hakomori
Keyword(s):  
Monoclonal Antibodies ◽  
Blood Group ◽  
Blood Group A ◽  
Group A

scholarly journals Immunochemical studies on blood groups LXII. Fractionation of hog and human A, H, and AH blood group active substance on insoluble immunoadsorbents of Dolichos and Lotus lectins.

1976 ◽  
Vol 143 (2) ◽  
pp. 422-436 ◽  
Author(s):  
M E Pereira ◽  
E A Kabat
Keyword(s):  
Blood Group ◽  
Optical Rotation ◽  
Gastric Mucin ◽  
Specific Optical Rotation ◽  
Dolichos Biflorus ◽  
Blood Group A ◽  
Analytical Properties ◽  
Group Substance ◽  
Group A

The purified lectins from Lotus tetragonolobus and Dolichos biflorus were coupled to Sepharose 2B to make insoluble adsorbents for purification and fractionation of blood group A and H active glycoproteins. With both adsorbents, hog gastric mucin A + H blood substance (HGM), purified by phenol-ethanol precipitation, yielded fractions showing only A, only H, or AH activities. The AH fraction was obtained when the adsorbent column was overloaded with HGM and its A and H specificities seem to be carried on the same molecules since they were not separable by chromatography on either column. However A and H specificities of blood group substance from the stomach of a presumably heterozygous individual hog were both on the same molecules as they too could not be fractionated on either column. Analytical properties of the isolated fractions were generally similar to those of the unfractionated material, the purfied A substances had a higher galactosamine/fucose ratio than did the H substances. Although the original A + H showed very little specific optical rotation, the separated A and H substances rotated positively and negatively, respectively. The lectin-Sepharose adsorbents have also proven useful in isolating A or H substances directly from the crude commercial hog gastric mucin. Blood group A2 substance from a human ovarian cyst yielded two fractions on the Lotus-Sepharose column; the effluent did not interact with the Lotus lectin but precipitated the Ulex and Dolichos lectins and anti-A, and appears to contain type 1 H determinants. The other fraction reacted with Lotus and Ulex lectin as well as with Dolichos and anti-A.

Synthesis of blood group A and B (type 2) tetrasaccharides. A strategy with fucosylation at the last stage

2020 ◽  
Vol 498 ◽  
pp. 108192
Author(s):  
Roman A. Kunetskiy ◽  
Galina V. Pazynina ◽  
Igor A. Ivanov ◽  
Nicolai V. Bovin
Keyword(s):  
Blood Group ◽  
Blood Group A ◽  
Group A ◽  
Last Stage

Identification of a blood group A active hexaglycosylceramide with a type 1 carbohydrate chain in plasma of an A1 Le(a-b-) secretor

1987 ◽  
Vol 257 (2) ◽  
pp. 409-415 ◽  
Author(s):  
P.-Å. Jovall ◽  
K. Lindström ◽  
I. Pascher ◽  
W. Pimlott ◽  
B.E. Samuelsson
Keyword(s):  
Blood Group ◽  
Carbohydrate Chain ◽  
Blood Group A ◽  
Group A

Blood group A determinants with mono- and difucosyl type 1 chain in human erythrocyte membranes

Biochemistry ◽  
1985 ◽  
Vol 24 (14) ◽  
pp. 3578-3586 ◽  
Author(s):  
Henrik Clausen ◽  
Steven B. Levery ◽  
John M. McKibbin ◽  
Senitiroh Hakomori
Keyword(s):  
Blood Group ◽  
Human Erythrocyte ◽  
Erythrocyte Membranes ◽  
Blood Group A ◽  
Human Erythrocyte Membranes ◽  
Group A
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