A vapor collection and thermal desorption method to measure semiochemical release rates from controlled release formulations

1980 ◽  
Vol 6 (4) ◽  
pp. 781-787 ◽  
Author(s):  
John H. Cross
Keyword(s):  
Controlled Release ◽  
Thermal Desorption ◽  
Release Rates ◽  
Controlled Release Formulations ◽  
Vapor Collection ◽  
Desorption Method

Effects of controlled-release formulations of atypical antipsychotics on functioning and quality of life of schizophrenic individuals

2012 ◽  
Vol 13 (11) ◽  
pp. 1631-1643
Author(s):  
Stefania Ruiu ◽  
Maria Antonietta Casu ◽  
Gianluca Casu ◽  
Sara Piras ◽  
Giorgio Marchese
Keyword(s):  
Quality Of Life ◽  
Controlled Release ◽  
Atypical Antipsychotics ◽  
Controlled Release Formulations

scholarly journals Sequential extraction and thermal desorption of mercury from contaminated soil and tailings from Mongolia

2012 ◽  
Vol 10 (5) ◽  
pp. 1565-1573 ◽  
Author(s):  
Pavel Coufalík ◽  
Pavel Krásenský ◽  
Marek Dosbaba ◽  
Josef Komárek
Keyword(s):  
Sequential Extraction ◽  
Thermal Desorption ◽  
Solid Phase ◽  
Extraction Procedure ◽  
Speciation Analysis ◽  
Water Soluble ◽  
Mercury Species ◽  
Different Temperatures ◽  
Acidic Conditions ◽  
Desorption Method

AbstractMercury forms in contaminated environmental samples were studied by means of sequential extraction and thermal desorption from the solid phase. The sequential extraction procedure involved the following fractions: water soluble mercury, mercury extracted in acidic conditions, mercury bound to humic substances, elemental Hg and mercury bound to complexes, HgS, and residual mercury. In addition to sequential extraction, the distribution of mercury species as a function of soil particles size was studied. The thermal desorption method is based on the thermal decomposition or desorption of Hg compounds at different temperatures. The following four species were observed: Hg0, HgCl2, HgS and Hg(II) bound to humic acids. The Hg release curves from artificial soils and real samples were obtained and their applicability to the speciation analysis was considered.

scholarly journals Modulating the Thermoresponse of Polymer-Protein Conjugates with Hydrogels for Controlled Release

Polymers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2772
Author(s):  
Vincent Huynh ◽  
Natalie Ifraimov ◽  
Ryan G. Wylie
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Ethylene Glycol ◽  
Solution Temperature ◽  
Residence Times ◽  
Release Rates ◽  
Critical Solution Temperature ◽  
Protein Conjugates ◽  
Particle Encapsulation ◽  
Glycol Methyl Ether

Sustained release is being explored to increase plasma and tissue residence times of polymer-protein therapeutics for improved efficacy. Recently, poly(oligo(ethylene glycol) methyl ether methacrylate) (PEGMA) polymers have been established as potential PEG alternatives to further decrease immunogenicity and introduce responsive or sieving properties. We developed a drug delivery system that locally depresses the lower critical solution temperature (LCST) of PEGMA-protein conjugates within zwitterionic hydrogels for controlled release. Inside the hydrogel the conjugates partially aggregate through PEGMA-PEGMA chain interactions to limit their release rates, whereas conjugates outside of the hydrogel are completely solubilized. Release can therefore be tuned by altering hydrogel components and the PEGMA’s temperature sensitivity without the need for traditional controlled release mechanisms such as particle encapsulation or affinity interactions. Combining local LCST depression technology and degradable zwitterionic hydrogels, complete release of the conjugate was achieved over 13 days.

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