Reaction of tetracyclone with the ethyl ester of phenylphosphonous acid

1979 ◽  
Vol 28 (6) ◽  
pp. 1258-1261 ◽  
Author(s):  
B. A. Arbuzov ◽  
A. V. Fuzhenkova ◽  
N. I. Galyutdinov
Keyword(s):  
Ethyl Ester ◽  
Phenylphosphonous Acid

Polymeric Micelles for the Delivery of Diclofenac and Its Ethyl Ester Derivative

2016 ◽  
Vol 4 (2) ◽  
pp. 109-119 ◽  
Author(s):  
Hanan Al-Lawati ◽  
Mohammad R. Vakili ◽  
Fakhreddin Jamali ◽  
Afsaneh Lavasanifar
Keyword(s):  
Ethyl Ester ◽  
Polymeric Micelles ◽  
Ester Derivative

Rat serum hydrolases cleaving N-acetyl-L-tyrosine ethyl ester

1974 ◽  
Vol 39 (7) ◽  
pp. 1925-1932
Author(s):  
E. Simonianová ◽  
M. Petáková
Keyword(s):  
Ethyl Ester ◽  
Rat Serum

Synthesis of Normuramic Acid Carba Analog and Its Glycopeptide Derivative Resistant to β-Elimination Splitting of the Side Chain

2000 ◽  
Vol 65 (11) ◽  
pp. 1726-1736 ◽  
Author(s):  
Miroslav Ledvina ◽  
Radka Pavelová ◽  
Anna Rohlenová ◽  
Jan Ježek ◽  
David Šaman
Keyword(s):  
Ethyl Ester ◽  
Alkaline Hydrolysis ◽  
Benzyl Ester ◽  
Side Chain ◽  
Propanoic Acid ◽  
Hydrolysis Of

Carba analogs of normuramic acid, i.e., 3-(benzyl 2-acetamido-2,3-dideoxy-4,6-O-isopropylidene-α-D-glucopyranosid-3-yl)propanoic acid derivatives (nitrile or esters) 3a-3c were prepared by addition of radicals generated from benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-3-O-[(methylsulfanyl)thiocarbonyl]- (2a) or -3-O-(phenoxythiocarbonyl)-α-D-glucopyranoside (2b) with Bu3SnH to acrylonitrile or acryl esters. Alkaline hydrolysis of ethyl ester 3c afforded 3-(benzyl 2-acetamido-2,3-dideoxy-4,6-O-isopropylidene-α-D-glucopyranosid-3-yl)propanoic acid (5). Coupling of acid 5 with L-2-aminobutanoyl-D-isoglutamine benzyl ester trifluoroacetate and subsequent deprotection of the intermediate 6 furnished N-[3-(2-acetamido-2,3-dideoxy-α-D-glucopyranosid-3-yl)propanoyl]-L-2-aminobutanoyl-D-isoglutamine (7).

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