An economical method of calculating Lagrange multiplier estimates for nonlinear programming problems when many of the constraints are bounds on the variables

1977 ◽  
Vol 21 (2) ◽  
pp. 235-239
Author(s):  
M. C. Bartholomew-Biggs
Keyword(s):  
Nonlinear Programming ◽  
Lagrange Multiplier ◽  
Economical Method

Reconsideration of Russian colloquialism from the perspective of Vietnamese language tradition

Litera ◽  
2020 ◽  
pp. 85-93
Author(s):  
Thuy Duong Trinh ◽  
Viktor Mikhailovich Shaklein
Keyword(s):  
Native Speaker ◽  
Theoretical Framework ◽  
Russian Language ◽  
Practical Significance ◽  
Educational Materials ◽  
Economical Method ◽  
Academic Fields ◽  
Special Meaning

This article is dedicated to one of the patterns in development of Russian colloquialism – reconsideration of the key meaning of casual words through metaphorization and metonymization. The goal of this work consists in examination of the trend inherent to Russian colloquialism throughout its evolution, which consists in transferring the meaning of casual words for their use in the field of term formation, as well as in analysis of this phenomenon from the perspective of a Vietnamese native speaker. The article studies the prerequisites that contribute to active use of the colloquialism in formation of special terminology; describes the process of transformation of the meaning of casual words for creating a new terminological meaning; considers the possibilities of formation of special meaning of casual words using metaphors and metonymy. The theoretical framework of this research is comprised of the works of Russian and Vietnamese linguists on reconsideration of colloquialism in term formation. Terms from the various academic fields served as the material for this research. The scientific novelty lies in interpretation of reconsideration of colloquialism as the most economical method for enriching Russian language vocabulary via potential of lexical unites present therein. Practical significance of this study is substantiated by the fact that the acquired results can be used in preparing special curricula, educational materials on lexicology, as well as in teaching Russian language as foreign to Vietnamese audience.

Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A

2019 ◽  
Author(s):  
Thomas Siemon ◽  
Zhangqian Wang ◽  
Guangkai Bian ◽  
Tobias Seitz ◽  
Ziling Ye ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Synthetic Biology ◽  
Chemical Synthesis ◽  
Building Block ◽  
Transient Receptor Potential ◽  
Receptor Potential ◽  
Economical Method ◽  
Englerin A ◽  
Transient Receptor

Herein, we report the semisynthetic production of the potent transient receptor potential canonical (TRPC) channel agonist (−)-englerin A (EA), using guaia-6,10(14)-diene as the starting material. Guaia-6,10(14)-diene was systematically engineered in Escherichia coli and Saccharomyces cerevisiae using the CRISPR/Cas9 system and produced with high titers. This provided us the opportunity to execute a concise chemical synthesis of EA and the two related guaianes (−)-oxyphyllol and (+)-orientalol E. The potentially scalable approach combines the advantages of synthetic biology and chemical synthesis and provides an efficient and economical method for producing EA as well as its analogs.

Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A

2019 ◽  
Author(s):  
Thomas Siemon ◽  
Zhangqian Wang ◽  
Guangkai Bian ◽  
Tobias Seitz ◽  
Ziling Ye ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Saccharomyces Cerevisiae ◽  
Synthetic Biology ◽  
Chemical Synthesis ◽  
Building Block ◽  
Transient Receptor Potential ◽  
Receptor Potential ◽  
Economical Method ◽  
Englerin A ◽  
Transient Receptor

Herein, we report the semisynthetic production of the potent transient receptor potential canonical (TRPC) channel agonist (−)-englerin A (EA), using guaia-6,10(14)-diene as the starting material. Guaia-6,10(14)-diene was systematically engineered in Escherichia coli and Saccharomyces cerevisiae using the CRISPR/Cas9 system and produced with high titers. This provided us the opportunity to execute a concise chemical synthesis of EA and the two related guaianes (−)-oxyphyllol and (+)-orientalol E. The potentially scalable approach combines the advantages of synthetic biology and chemical synthesis and provides an efficient and economical method for producing EA as well as its analogs.

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