Reduced cellular immunity to varicella zoster virus during treatment for acute lymphoblastic leukemia of childhood:In Vitro studies of possible mechanisms

1986 ◽  
Vol 6 (6) ◽  
pp. 472-480 ◽  
Author(s):  
Roger H. Giller ◽  
Raleigh A. Bowden ◽  
Myron J. Levin ◽  
Lynn J. Walker ◽  
David G. Tubergen ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Varicella Zoster Virus ◽  
Cellular Immunity ◽  
Lymphoblastic Leukemia ◽  
Varicella Zoster

Fulminant Hepatitis Due to Varicella Zoster Virus in a Girl With Acute Lymphoblastic Leukemia in Remission

2005 ◽  
Vol 27 (10) ◽  
pp. 551-553 ◽  
Author(s):  
Elpis Mantadakis ◽  
Nicole Anagnostatou ◽  
Vassiliki Danilatou ◽  
Erasmia-Athina Markaki ◽  
Anna-Maria Spanaki ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Varicella Zoster Virus ◽  
Fulminant Hepatitis ◽  
Lymphoblastic Leukemia ◽  
Varicella Zoster

Noncutaneous varicella-zoster virus (VZV) infection with fatal liver failure in a child with acute lymphoblastic leukemia (ALL)

2001 ◽  
Vol 37 (2) ◽  
pp. 145-147 ◽  
Author(s):  
Ingo Müller ◽  
Christian Aepinus ◽  
Robert Beck ◽  
Burkard Bültmann ◽  
Dietrich Niethammer ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Liver Failure ◽  
Varicella Zoster Virus ◽  
Lymphoblastic Leukemia ◽  
Varicella Zoster ◽  
Fatal Liver ◽  
Fatal Liver Failure

Varicella‐zoster virus infection in the pediatric population with acute lymphoblastic leukemia in Poland

2020 ◽  
Vol 92 (12) ◽  
pp. 3645-3649
Author(s):  
Joanna Zawitkowska ◽  
Monika Lejman ◽  
Anna Szmydki‐Baran ◽  
Agnieszka Zaucha‐Prażmo ◽  
Krzysztof Czyżewski ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Virus Infection ◽  
Varicella Zoster Virus ◽  
Pediatric Population ◽  
Lymphoblastic Leukemia ◽  
Varicella Zoster Virus Infection ◽  
Varicella Zoster

scholarly journals Studies on transfer of varicella-zoster-virus specific T-cell immunity from bone marrow donor to recipient

Blood ◽  
1990 ◽  
Vol 75 (3) ◽  
pp. 806-809 ◽  
Author(s):  
S Kato ◽  
H Yabe ◽  
M Yabe ◽  
M Kimura ◽  
M Ito ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
T Cell ◽  
Varicella Zoster Virus ◽  
Cellular Immunity ◽  
Marrow Transplantation ◽  
T Cell Immunity ◽  
Lymphoproliferative Response ◽  
Varicella Zoster ◽  
Cell Immunity

Abstract The transfer of antigen-specific cellular immunity in human bone marrow transplantation (BMT) was studied in 49 donor-recipient pairs, using a varicella-zoster-virus (VZV) specific lymphoproliferative response (LPR) assay. Posttransplant VZV-LPR could be serially measured in 31 long-term surviving recipients. VZV-specific T-cell immunity was detected in the early posttransplant period in 4 of 16 recipients who were, and whose donors were, immune to VZV before BMT, but two of those positive responses diminished in the first 100 days posttransplant. No positive response was detected in the immediate posttransplant period when either only the recipient or the donor was immune to VZV pretransplant. Herpes zoster or chickenpox developed in the recipients depending on a history of pretransplant VZV infection when the VZV-LPR became negative, and recovery from VZV infection was always followed by quick conversion of VZV-LPR. Long-lasting positive VZV-LPR was observed in the two recipients who experienced VZV infection in the immediate pretransplant period and received marrow graft from an immune donor. Our results indicate that a simple or direct transfer of VZV-specific cellular immunity from a marrow donor to a recipient cannot be expected in usual clinical bone marrow transplantation and that there might be a collaboration or recruitment of immune responses involving both donor and recipient that permits the VZV-LPR to remain positive posttransplant.

scholarly journals Altered Phenotype and Functionality of Varicella Zoster Virus–Specific Cellular Immunity in Individuals With Active Infection

2014 ◽  
Vol 211 (4) ◽  
pp. 600-612 ◽  
Author(s):  
David Schub ◽  
Eva Janssen ◽  
Sarah Leyking ◽  
Urban Sester ◽  
Gunter Assmann ◽  
...  
Keyword(s):  
Varicella Zoster Virus ◽  
Cellular Immunity ◽  
Active Infection ◽  
Varicella Zoster
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