Structure changes of the enterochromaffin cells of the small intestine of guinea pigs under the influence of rotundin

1964 ◽  
Vol 58 (1) ◽  
pp. 865-867
Author(s):  
I. V. Skorodumova ◽  
V. V. Berezhinskaya
Keyword(s):  
Small Intestine ◽  
Guinea Pigs ◽  
Enterochromaffin Cells ◽  
Structure Changes

In vitro absorption of bile salts by small intestine of rats and guinea pigs

1961 ◽  
Vol 200 (2) ◽  
pp. 313-317 ◽  
Author(s):  
Leon Lack ◽  
I. M. Weiner
Keyword(s):  
Small Intestine ◽  
Bile Acid ◽  
Active Transport ◽  
Sodium Azide ◽  
Concentration Gradient ◽  
Guinea Pigs ◽  
Bile Salts ◽  
Ileal Segment

The transport of taurocholic and glycocholic acids by the small intestine of rats and guinea pigs against a concentration gradient was studied by the everted gutsac technique. Transport of these substances is limited to the distal ileal segment. This transport is inhibited by anoxia, dinitrophenol and sodium azide. The system has a transport maximum. On the basis of these criteria bile acid reabsorption is considered to occur by active transport.

scholarly journals Morphoquantitative study of the submucous plexus (of Meissner) of the jejunum-ileum of young and old guinea pigs

2011 ◽  
Vol 69 (1) ◽  
pp. 85-90 ◽  
Author(s):  
Marcelo César Zanesco ◽  
Romeu Rodrigues de Souza
Keyword(s):  
Small Intestine ◽  
Guinea Pigs ◽  
Age Groups ◽  
Collagen Fibers ◽  
Submucous Plexus ◽  
The Mean ◽  
Electronic Microscope

OBJECTIVE: To study the aging of submucous plexus of the small intestine (jejunum-ileum) of the guinea pigs from the quantitative, structural and ultrastructural perspective. METHOD: Chemical preparations of membrane of the jejunum-ileum of old and young animals with the use of light and electronic microscope. RESULTS: The ganglia of young animals presented between 1 and 56 neurons and the old animals presented from 1 to 30 neurons. The mean density of the ganglia by cm² in the young jejunum-ileum was of 551±36.89 and in the old one 413±11.86. The density of the neurons was 5011±291.11 neurons/cm² average in young animals and 2918±120.70 neurons/cm² in the old ones. The size of the neurons varied in both age groups. The collagen fibers in the ganglia of old animals they were condensed. Degenerated mitochondrias in the interior of the cell were frequent in the old animals. CONCLUSION: In submucous plexus of the jejunum-ileum there is a loss of 38% of the neurons with aging.

scholarly journals Гістоморфологічні зміни в органах і тканинах мурчаків, інфікованих ентеротоксигенними штамами Y. Enterocoliticа

2015 ◽  
pp. 73-83
Author(s):  
Б. В. Борисевич ◽  
В. Г. Скибіцький ◽  
Г. В. Козловська ◽  
А. В. Козловська
Keyword(s):  
Small Intestine ◽  
Lymph Nodes ◽  
Causative Agent ◽  
Guinea Pigs ◽  
Degenerative Changes ◽  
Necrotic Enteritis ◽  
Immune Organs ◽  
Liver And Pancreas ◽  
Histomorphological Changes ◽  
Significant Activation

Викладено результати дослідження гістоморфо-логічних змін органів і тканин мурчаків, інфікованихентеротоксигенними штамами Y. enterocoliticа. Зок-рема встановлено, що найбільше уражається тонкакишка, де виявляють поверхневий некротичний енте-рит. Токсини збудника хвороби, потрапляючи в кров,спричиняють дистрофічні зміни в печінці та підшлун-ковій залозі, спричиняють екстракапілярний серознийгломерулонефрит та дистрофічні зміни епітеліюканальців нирок, а також серозний міокардит. Інфі-кування мурчаків призводить до значної активаціївсіх імунокомпетентних органів організму – тимусу,селезінки, соматичних і вісцеральних лімфовузлів. The results of the study of histomorphological changes in organs and tissues of guinea pigs infected with enterotoxigenic strains of Y. enterocolitica were presented. We established, in particular, the most affected in small intestine, where superficial necrotic enteritis was determined. Toxins are causative agent, getting into the bloodstream cause degenerative changes in the liver and pancreas. And also serous ecstracapillary glomerulonephritis and degenerated changes of epithelial tubules of the kidneys and serous myocarditis were caused. The infecting of guinea pigs leads significant activation of immune organs: thymus, spleen, somatic and visceral lymph nodes.

Gastrointestinal myoelectric activity in conscious guinea pigs

1985 ◽  
Vol 249 (1) ◽  
pp. G92-G99 ◽  
Author(s):  
J. J. Galligan ◽  
M. Costa ◽  
J. B. Furness
Keyword(s):  
Small Intestine ◽  
Guinea Pigs ◽  
Mammalian Species ◽  
Gastric Antrum ◽  
Slow Waves ◽  
Cycle Period ◽  
Myoelectric Activity ◽  
Phase 3 ◽  
Fed State ◽  
Intestinal Slow Waves

Myoelectric activity was recorded from the gastric antrum and small intestine of conscious, unrestrained guinea pigs using bipolar Ag-Ag chloride electrodes that had been previously implanted under pentobarbital sodium/Innovar anesthesia. In fasted guinea pigs, the migrating myoelectric complex (MMC) was recorded from the small intestine and was observed to propagate aborally at a speed that declined with distance from the pylorus (range of speeds of the front of phase 3: 17.5 cm/min in the duodenum to 4.1 cm/min in the ileum). The complex was not disrupted by feeding but occurred less frequently in the freely fed state (82-min cycle period in the fasted state versus 139 min in the fed state). The complex started in the duodenum and was accompanied by a brief (6.3 +/- 0.9 min) period of inhibition of antral myoelectric activity. Slow waves were also recorded from the gastric antrum (10.3 +/- 1.3/min) and the small intestine. The frequency of intestinal slow waves was uniform along the length of the bowel (26.2 +/- 1.3/min in the duodenum to 24.7 +/- 1.3/min in the ileum). It is concluded that the guinea pig is similar to other mammalian species, so far examined, in its pattern of gastrointestinal myoelectric activity.

Experimental Studies of Effects of Acupuncture on Enterochromaffin Cells: Guinea Pig Enterochromaffin Cell Count After Electro-Acupuncture

1980 ◽  
Vol 08 (03) ◽  
pp. 290-296 ◽  
Author(s):  
Yann-Ching Hwang
Keyword(s):  
Guinea Pig ◽  
Cell Count ◽  
Guinea Pigs ◽  
Experimental Studies ◽  
Treated Group ◽  
Enterochromaffin Cells ◽  
Longissimus Dorsi ◽  
Acupuncture Points ◽  
Enterochromaffin Cell

Guinea pig acupuncture points located on the back of the animal, cranial and caudal to the last rib in the muscular groove between longissimus dorsi and iliocostalis, were treated by electro-acupuncture (EA). In the duodenum, when compared with the control, the EA-treated group showed a significant decrease of its enterochromaffin (EC) cell count. However, the sham-treated group also had a lower EC cell count compared to the control. Decreased EC counts were also observed in the jejunum and colon in both EA and sham treated groups: however, they were not significant except in the sham-treated colon. The present study demonstrated that in the normal guinea pigs electro-acupuncture on certain points tends to cause a decrease of the EC cell count in some parts of the gut; however, such results cannot be completely attributed to the effect of acupuncture.

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