Cell fusions during formation of the oocyte-nurse chamber complex in the ovary of the dipteran insectMycophila speyeri

1983 ◽  
Vol 192 (5) ◽  
pp. 228-233 ◽  
Author(s):  
Peter Michael Sch�pbach ◽  
Dirk Frederik Went
Keyword(s):  
1990 ◽  
Vol 52 (4) ◽  
pp. 839-841
Author(s):  
Eiichi HONDA ◽  
Hironori TAKAHASHI ◽  
Katsunori OKAZAKI ◽  
Tetsuo KUMAGAI

Author(s):  
Daria Miroshnychenko ◽  
Etienne Baratchart ◽  
Meghan C. Ferrall-Fairbanks ◽  
Robert Vander Velde ◽  
Mark A. Laurie ◽  
...  

2013 ◽  
Vol 2 (9) ◽  
pp. e25994 ◽  
Author(s):  
shigeo koido ◽  
Sadamu Homma ◽  
Masato Okamoto ◽  
Yoshihisa Namiki ◽  
Kazuki Takakura ◽  
...  

2020 ◽  
Author(s):  
Muhammad Roomi ◽  
Yaser Khan

<p>The ongoing search to contain and control the spread of COVID-19 disease focuses on discovering drugs or vaccines that can play an essential role in treating this contagious disease. This paper focuses on natural compounds that can play a vital role in the treatment of Covid-19. The study spans over the chemicals that have the potential to bind with the key residues of type II Transmembrane Protease Serine (TMPRSS2). TMPRSS2 can be termed as the catalyst that cleaves the spike glycoproteins of Sars-Cov-2, which causes the replication and spread of virus inside the human body by facilitating virus-cell fusions. Drugs like Camostat Mesylate, Aprotinin, and Rimantadine have been proposed as potential inhibitors of TMPRSS2. After screening large sets of phytochemicals and flavonoids extracted from plants, potential compounds have been tested, and a set of most effective and suitable compounds are chosen for further studies. These selected compounds are further analyzed in terms of binding with key residues as well as high binding affinity with TMPRSS2. The in silico analysis of possible chemical compounds is carried out by using docking, screening analysis, Molecular Dynamics, and Electrostatic Potential Simulations. Chemicals extracted from different plants are comparatively analyzed with drugs like Aprotinin, Camostat Mesylate, and Rimantadine.</p>


Development ◽  
1998 ◽  
Vol 125 (23) ◽  
pp. 4809-4819 ◽  
Author(s):  
L. Nilsson ◽  
X. Li ◽  
T. Tiensuu ◽  
R. Auty ◽  
I. Greenwald ◽  
...  

Induction of vulval fates in the C. elegans hermaphrodite is mediated by a signal transduction pathway involving Ras and MAP kinase. Previous genetic analysis has suggested that two potential targets of this pathway in the vulva precursor cells are two novel proteins, LIN-25 and SUR-2. In this report, we describe further studies of lin-25. The results of a genetic mosaic analysis together with those of experiments in which lin-25 was expressed under the control of an heterologous promoter suggest that the major focus of lin-25 during vulva induction is the vulva precursor cells themselves. We have generated antisera to LIN-25 and used these to analyse the pattern of protein expression. LIN-25 is present in all six precursor cells prior to and during vulva induction but later becomes restricted to cells of the vulval lineages. Mutations in genes in the Ras/MAP kinase pathway do not affect the pattern of expression but the accumulation of LIN-25 is reduced in the absence of sur-2. Overexpression of LIN-25 does not rescue sur-2 mutant defects suggesting that LIN-25 and SUR-2 may function together. LIN-25 is also expressed in the lateral hypodermis. Overexpression of LIN-25 disrupts lateral hypodermal cell fusion, suggesting that lin-25 may play a role in regulating cell fusions in C. elegans.


2006 ◽  
Vol 63 (16) ◽  
pp. 1906-1911 ◽  
Author(s):  
B. Bjerregaard ◽  
S. Holck ◽  
I. J. Christensen ◽  
L. -I. Larsson

Cell Reports ◽  
2015 ◽  
Vol 11 (10) ◽  
pp. 1549-1563 ◽  
Author(s):  
Ying Su ◽  
Ashim Subedee ◽  
Noga Bloushtain-Qimron ◽  
Virginia Savova ◽  
Marcin Krzystanek ◽  
...  

1995 ◽  
Vol 27 (6) ◽  
pp. 550-554 ◽  
Author(s):  
Masaki Fukuda ◽  
Yukiko Harada ◽  
Satoko Imahori ◽  
Yukitaka Fukumasa-Nakai ◽  
Yasuo Hayashi

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