Synthesis of glycerol derivatives of oligomers with functional groups at the ends of the molecules

1965 ◽  
Vol 14 (6) ◽  
pp. 985-987
Author(s):  
K. A. Andrianov ◽  
N. I. Tsomaya ◽  
L. M. Khananashvili
Keyword(s):  
Functional Groups ◽  
Derivatives Of

scholarly journals Cinnamic Acid Derivatives as α-Glucosidase Inhibitor Agents

2017 ◽  
Vol 17 (1) ◽  
pp. 151 ◽  
Author(s):  
Teni Ernawati ◽  
Maksum Radji ◽  
Muhammad Hanafi ◽  
Abdul Mun’im ◽  
Arry Yanuar
Keyword(s):  
Functional Groups ◽  
Cinnamic Acid ◽  
Phenyl Group ◽  
Chemical Compounds ◽  
Cinnamic Acid Derivative ◽  
Cinnamic Acid Derivatives ◽  
Glucosidase Inhibitor ◽  
Glucosidase Inhibitors ◽  
Derivatives Of ◽  
Additive Reaction

This paper reviews biological activity of some cinnamic acid derivative compounds which are isolated from natural materials and synthesized from the chemical compounds as an agent of α-glucosidase inhibitors for the antidiabetic drug. Aegeline, anhydroaegeline and aeglinoside B are natural products isolated compounds that have potential as an α-glucosidase inhibitor. Meanwhile, α-glucosidase inhibitor class of derivatives of cinnamic acid synthesized compounds are p-methoxy cinnamic acid and p-methoxyethyl cinnamate. Chemically, cinnamic acid has three main functional groups: first is the substitution of the phenyl group, second is the additive reaction into the α-β unsaturated, and third is the chemical reaction with carboxylic acid functional groups. The synthesis and modification of the structure of cinnamic acid are very influential in inhibitory activity against α-glucosidase.

Polarographic half-wave potentials and ultraviolet absorption spectra of some conjugated heteroenoid compounds

1969 ◽  
Vol 47 (21) ◽  
pp. 4076-4083 ◽  
Author(s):  
H. L. Holmes ◽  
D. J. Currie
Keyword(s):  
Absorption Spectra ◽  
Functional Groups ◽  
Ultraviolet Absorption ◽  
Half Wave ◽  
Active Methylene Compounds ◽  
Derivatives Of ◽  
Active Methylene ◽  
Hammett Relationship

The half-wave potentials of phenyl substituted derivatives for each series of conjugated heteroenoid compounds studied follow a Hammett relationship. The effect of change in the functional groups and of increase in length of the conjugated system upon half-wave potentials and ultraviolet absorption maxima is briefly discussed. Terephthalylidene derivatives of active methylene compounds function like the cinnamylidene derivatives.

Preparation of trimethylsilyl derivatives of substituted hydrazones containing functional groups

1983 ◽  
Vol 32 (6) ◽  
pp. 1282-1284 ◽  
Author(s):  
A. V. Kalinin ◽  
�. T. Apasov ◽  
S. V. Bugaeva ◽  
S. L. Ioffe ◽  
V. A. Tartakovskii
Keyword(s):  
Functional Groups ◽  
Trimethylsilyl Derivatives ◽  
Derivatives Of

Design and reactivity of organic functional groups—utility of imidazolylsulfonates in the synthesis of monobactams and 3-amino nocardicinic acid

1985 ◽  
Vol 63 (12) ◽  
pp. 3613-3617 ◽  
Author(s):  
Stephen Hanessian ◽  
Claude Couture ◽  
Heinz Wyss
Keyword(s):  
Functional Groups ◽  
Intramolecular Cyclization ◽  
Leaving Group ◽  
Organic Functional Groups ◽  
Derivatives Of

The imidazolylsulfonate group has been found to be a versatile leaving group in the intramolecular cyclization of p-methoxyphenyl amides and related derivatives of N-substituted L-serine to give the corresponding β-lactams.

Novel Ciprofloxacin Derivatives for Polymer-Based Drug Delivery Systems

2018 ◽  
Vol 762 ◽  
pp. 36-41
Author(s):  
Tatjana Gerasimova ◽  
Vitālijs Rjabovs ◽  
Māris Turks
Keyword(s):  
Drug Delivery ◽  
Functional Groups ◽  
Drug Delivery Systems ◽  
Synthetic Polymers ◽  
Delivery Systems ◽  
Covalent Attachment ◽  
Fluoroquinolone Antibiotic ◽  
Derivatives Of

Novel derivatives of fluoroquinolone antibiotic ciprofloxacin were synthesized. The modifications of both the N- and C-termini were focused on introduction of functionalized linkers that can be used for covalent attachment to natural or synthetic polymers with appropriate functional groups.

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