5-Iododeoxyuridine, like 5-bromodeoxyuridine, induces specific dicentric chromosome formation in cells with micronuclei

1987 ◽  
Vol 104 (1) ◽  
pp. 977-979
Author(s):  
V. I. Stobetskii ◽  
Yu. Kh. Khapchaev ◽  
L. L. Mironova
Keyword(s):  
Dicentric Chromosome ◽  
Cells With Micronuclei ◽  
Chromosome Formation ◽  
In Cells

scholarly journals Increase in dicentric chromosome formation after a single CT scan in adults

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Yu Abe ◽  
Tomisato Miura ◽  
Mitsuaki A. Yoshida ◽  
Risa Ujiie ◽  
Yumiko Kurosu ◽  
...  
Keyword(s):  
Ct Scan ◽  
Dicentric Chromosome ◽  
Chromosome Formation

scholarly journals The Role of Replication Bypass Pathways in Dicentric Chromosome Formation in Budding Yeast

Genetics ◽  
2010 ◽  
Vol 186 (4) ◽  
pp. 1161-1173 ◽  
Author(s):  
Andrew L. Paek ◽  
Hope Jones ◽  
Salma Kaochar ◽  
Ted Weinert
Keyword(s):  
Budding Yeast ◽  
Dicentric Chromosome ◽  
Chromosome Formation

Dicentric Chromosome Formation and Epigenetics of Centromere Formation in Plants

2012 ◽  
Vol 39 (3) ◽  
pp. 125-130 ◽  
Author(s):  
Shulan Fu ◽  
Zhi Gao ◽  
James Birchler ◽  
Fangpu Han
Keyword(s):  
Dicentric Chromosome ◽  
Chromosome Formation

scholarly journals Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae

1989 ◽  
Vol 9 (3) ◽  
pp. 1368-1370
Author(s):  
A Hill ◽  
K Bloom
Keyword(s):  
Saccharomyces Cerevisiae ◽  
High Frequency ◽  
Dicentric Chromosome ◽  
Dicentric Chromosomes ◽  
Chromosome Iii ◽  
Derivatives Of ◽  
In Cells

The introduction of a conditional centromere into chromosome III of Saccharomyces cerevisiae provided an opportunity to evaluate phenotypic and karyotypic consequences in cells harboring dicentric chromosomes upon entry into mitosis. A mitotic pause ensued, and monocentric derivatives of chromosome III were generated at a high frequency.

scholarly journals Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae.

1989 ◽  
Vol 9 (3) ◽  
pp. 1368-1370 ◽  
Author(s):  
A Hill ◽  
K Bloom
Keyword(s):  
Saccharomyces Cerevisiae ◽  
High Frequency ◽  
Dicentric Chromosome ◽  
Dicentric Chromosomes ◽  
Chromosome Iii ◽  
Derivatives Of ◽  
In Cells

The introduction of a conditional centromere into chromosome III of Saccharomyces cerevisiae provided an opportunity to evaluate phenotypic and karyotypic consequences in cells harboring dicentric chromosomes upon entry into mitosis. A mitotic pause ensued, and monocentric derivatives of chromosome III were generated at a high frequency.

Cytoplasmic Tubules in Cells Infected with Laryngotracheitis Virus

1969 ◽  
Vol 27 ◽  
pp. 376-377
Author(s):  
A. M. Watrach
Keyword(s):  
Tissue Culture ◽  
Small Proportion ◽  
Chicken Embryo ◽  
Culture Cells ◽  
Tissue Culture Cells ◽  
Morphologic Characteristics ◽  
Infectious Laryngotracheitis ◽  
Laryngotracheitis Virus ◽  
In Cells

During a study of the development of infectious laryngotracheitis (LT) virus in tissue culture cells, unusual tubular formations were found in the cytoplasm of a small proportion of the affected cells. It is the purpose of this report to describe the morphologic characteristics of the tubules and to discuss their possible association with the development of virus.The source and maintenance of the strain of LT virus have been described. Prior to this study, the virus was passed several times in chicken embryo kidney (CEK) tissue culture cells.

Effect of Some Metabolic Inhibitors on Vinblastine-Induced Ribosomal-Granular Material Complexes

1971 ◽  
Vol 29 ◽  
pp. 548-549
Author(s):  
Awtar Krishan ◽  
Dora Hsu
Keyword(s):  
Granular Material ◽  
Rna Synthesis ◽  
Culture Medium ◽  
Actinomycin D ◽  
Metabolic Inhibitors ◽  
Protein And Rna Synthesis ◽  
Apparent Reduction ◽  
Plant Alkaloids ◽  
In Cells

Cells exposed to antitumor plant alkaloids, vinblastine and vincristine sulfate have large proteinacious crystals and complexes of ribosomes, helical polyribosomes and electron-dense granular material (ribosomal complexes) in their cytoplasm, Binding of H3-colchicine by the in vivo crystals shows that they contain microtubular proteins. Association of ribosomal complexes with the crystals suggests that these structures may be interrelated.In the present study cultured human leukemic lymphoblasts (CCRF-CEM), were incubated with protein and RNA-synthesis inhibitors, p. fluorophenylalanine, puromycin, cycloheximide or actinomycin-D before the addition of crystal-inducing doses of vinblastine to the culture medium. None of these compounds could completely prevent the formation of the ribosomal complexes or the crystals. However, in cells pre-incubated with puromycin, cycloheximide, or actinomycin-D, a reduction in the number and size of the ribosomal complexes was seen. Large helical polyribosomes were absent in the ribosomal complexes of cells treated with puromycin, while in cells exposed to cycloheximide, there was an apparent reduction in the number of ribosomes associated with the ribosomal complexes (Fig. 2).

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