Correction of metabolic disturbances in experimental cirrhosis of the liver by cryosurgical destruction and plasma flow resection

1989 ◽  
Vol 107 (5) ◽  
pp. 698-701 ◽  
Author(s):  
N. P. Mikaelyan ◽  
I. V. Stupin ◽  
I. V. Sleta
Keyword(s):  
Plasma Flow ◽  
Cirrhosis Of The Liver ◽  
Metabolic Disturbances ◽  
Experimental Cirrhosis ◽  
Cryosurgical Destruction

Collagenolytic activity in experimental cirrhosis of the liver

1987 ◽  
Vol 47 (3) ◽  
pp. 300-308 ◽  
Author(s):  
Ruy Perez-Tamayo ◽  
Irmgard Montfort ◽  
Elvira Gonzalez
Keyword(s):  
Cirrhosis Of The Liver ◽  
Collagenolytic Activity ◽  
Experimental Cirrhosis

Dynamics of ascites formation in rats with experimental cirrhosis

1980 ◽  
Vol 238 (5) ◽  
pp. F353-F357 ◽  
Author(s):  
J. M. Lopez-Novoa ◽  
M. A. Rengel ◽  
L. Hernando
Keyword(s):  
Renal Function ◽  
Glomerular Filtration Rate ◽  
Plasma Flow ◽  
Filtration Rate ◽  
Hepatic Cirrhosis ◽  
Renal Plasma Flow ◽  
Sodium Balance ◽  
Partial Removal ◽  
Experimental Cirrhosis ◽  
Ascites Formation

Renal function, sodium balance, and ascites formation were observed during induction in rats of experimental cirrhosis. The same variables were studied after partial removal of the ascites in rats with experimental cirrhosis. Glomerular filtration rate (GFR) and effective renal plasma flow (RPF) did not change during hepatic cirrhosis development. Positive sodium balance significantly higher than that observed in controls preceded the appearance of ascites for a period of about 2 wk. When the ascites was removed, GFR, RPF and positive Na balance did not change if Na intake remained constant. Ascites reformation rate was largely dependent on sodium balance. These data strongly support the "overflow" theory of ascites formation and are difficult to reconcile with the classical "underfilling" theory.

Interstitial dynamics in rats with early stage experimental cirrhosis of the liver

1989 ◽  
Vol 256 (3) ◽  
pp. F497-F503
Author(s):  
E. Sanz ◽  
C. Caramelo ◽  
J. M. Lopez-Novoa
Keyword(s):  
Sodium Excretion ◽  
Interstitial Fluid ◽  
Early Stage ◽  
Fluid Pressure ◽  
Extracellular Fluid ◽  
Ringer Solution ◽  
Urine Flow ◽  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis ◽  
Albumin Infusion

Pathogenesis of edema in cirrhosis of the liver is still incompletely understood. The present study was designed to examine interstitial fluid dynamics in cirrhotic, non-ascitic rats, measuring interstitial fluid pressure by means of a subcutaneous plastic capsule in basal conditions during extracellular fluid volume expansion with Ringer solution and during albumin infusion. Urine flow and sodium excretion and plasma and interstitial fluid volumes were simultaneously measured. Cirrhotic rats exhibited reduced urine flow and sodium excretion, both in basal conditions and in response to expansion maneuvers. Plasma and interstitial fluid volumes were higher in cirrhotic than in control animals. Remarkable alterations were present in capsular pressures in cirrhotic rats. In the control rats, basal capsular pressure values were negative, and they increased after Ringer infusion and markedly decreased with albumin infusion. In contrast, in cirrhotic rats, basal capsular pressures were in the positive range and they remained nearly constant during ringer infusion and albumin administration. These results suggest that in cirrhotic rats there are significant alterations in systemic interstitial dynamics, even before ascites formation. Altered systemic capillary dynamics may therefore be important early changes that precede and thus contribute to the formation of edema in cirrhosis.

Studies on suppression of experimental cirrhosis of the liver

1969 ◽  
Vol 4 (2) ◽  
pp. 158-158
Author(s):  
A. Yoshioka ◽  
K. Shimizu ◽  
Y. Sawada ◽  
T. Sakamaki ◽  
K. Kuramochi
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis

Effect of liver RNA on the course of experimental cirrhosis of the liver

1970 ◽  
Vol 70 (4) ◽  
pp. 1112-1114 ◽  
Author(s):  
A. M. Chernukh ◽  
E. D. Vyshepan ◽  
I. L. Razumova ◽  
N. N. Alekseeva ◽  
N. S. Chinenova
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis

EXPERIMENTAL CIRRHOSIS OF THE LIVER IN PRIMATES

The Lancet ◽  
1959 ◽  
Vol 273 (7062) ◽  
pp. 26-27 ◽  
Author(s):  
GeorgeF. Wilgram ◽  
W.J. Russell Taylor
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis

Experimental cirrhosis of the liver produced by dysentery toxin

1972 ◽  
Vol 73 (4) ◽  
pp. 378-380
Author(s):  
M. N. Khanin ◽  
I. A. Alimova ◽  
M. K. Irgashev
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis ◽  
Dysentery Toxin
Sign in / Sign up

Export Citation Format

Share Document