Studies on suppression of experimental cirrhosis of the liver

1969 ◽  
Vol 4 (2) ◽  
pp. 158-158
Author(s):  
A. Yoshioka ◽  
K. Shimizu ◽  
Y. Sawada ◽  
T. Sakamaki ◽  
K. Kuramochi
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis

Collagenolytic activity in experimental cirrhosis of the liver

1987 ◽  
Vol 47 (3) ◽  
pp. 300-308 ◽  
Author(s):  
Ruy Perez-Tamayo ◽  
Irmgard Montfort ◽  
Elvira Gonzalez
Keyword(s):  
Cirrhosis Of The Liver ◽  
Collagenolytic Activity ◽  
Experimental Cirrhosis

Interstitial dynamics in rats with early stage experimental cirrhosis of the liver

1989 ◽  
Vol 256 (3) ◽  
pp. F497-F503
Author(s):  
E. Sanz ◽  
C. Caramelo ◽  
J. M. Lopez-Novoa
Keyword(s):  
Sodium Excretion ◽  
Interstitial Fluid ◽  
Early Stage ◽  
Fluid Pressure ◽  
Extracellular Fluid ◽  
Ringer Solution ◽  
Urine Flow ◽  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis ◽  
Albumin Infusion

Pathogenesis of edema in cirrhosis of the liver is still incompletely understood. The present study was designed to examine interstitial fluid dynamics in cirrhotic, non-ascitic rats, measuring interstitial fluid pressure by means of a subcutaneous plastic capsule in basal conditions during extracellular fluid volume expansion with Ringer solution and during albumin infusion. Urine flow and sodium excretion and plasma and interstitial fluid volumes were simultaneously measured. Cirrhotic rats exhibited reduced urine flow and sodium excretion, both in basal conditions and in response to expansion maneuvers. Plasma and interstitial fluid volumes were higher in cirrhotic than in control animals. Remarkable alterations were present in capsular pressures in cirrhotic rats. In the control rats, basal capsular pressure values were negative, and they increased after Ringer infusion and markedly decreased with albumin infusion. In contrast, in cirrhotic rats, basal capsular pressures were in the positive range and they remained nearly constant during ringer infusion and albumin administration. These results suggest that in cirrhotic rats there are significant alterations in systemic interstitial dynamics, even before ascites formation. Altered systemic capillary dynamics may therefore be important early changes that precede and thus contribute to the formation of edema in cirrhosis.

Effect of liver RNA on the course of experimental cirrhosis of the liver

1970 ◽  
Vol 70 (4) ◽  
pp. 1112-1114 ◽  
Author(s):  
A. M. Chernukh ◽  
E. D. Vyshepan ◽  
I. L. Razumova ◽  
N. N. Alekseeva ◽  
N. S. Chinenova
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis

EXPERIMENTAL CIRRHOSIS OF THE LIVER IN PRIMATES

The Lancet ◽  
1959 ◽  
Vol 273 (7062) ◽  
pp. 26-27 ◽  
Author(s):  
GeorgeF. Wilgram ◽  
W.J. Russell Taylor
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis

Experimental cirrhosis of the liver produced by dysentery toxin

1972 ◽  
Vol 73 (4) ◽  
pp. 378-380
Author(s):  
M. N. Khanin ◽  
I. A. Alimova ◽  
M. K. Irgashev
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis ◽  
Dysentery Toxin

Effects of BN 52021 on hemodynamics on rats with experimental cirrhosis of the liver

1985 ◽  
Vol 30 (4) ◽  
pp. 717
Author(s):  
L.M. Villamediana ◽  
E. Sanz ◽  
C. Caramelo ◽  
S. Fernandez-Gallardo ◽  
M. Sanchez-Crespo ◽  
...  
Keyword(s):  
Cirrhosis Of The Liver ◽  
Experimental Cirrhosis
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