Effect of the hexapeptide dalargin on ornithine decarboxylase activity in the duodenal mucosa of rats with experimental duodenal ulcer

1987 ◽  
Vol 103 (3) ◽  
pp. 356-358
Author(s):  
K. N. Yarygin ◽  
A. G. Shitin ◽  
V. M. Polonskii ◽  
V. A. Vinogradov
Keyword(s):  
Duodenal Ulcer ◽  
Ornithine Decarboxylase ◽  
Duodenal Mucosa ◽  
Decarboxylase Activity ◽  
Ornithine Decarboxylase Activity ◽  
Experimental Duodenal Ulcer

scholarly journals Ornithine decarboxylase activity in chick duodenum induced by 1 α, 25-dihydroxycholecalciferol

1981 ◽  
Vol 195 (3) ◽  
pp. 685-690 ◽  
Author(s):  
T Shinki ◽  
N Takahashi ◽  
C Miyaura ◽  
K Samejima ◽  
Y Nishii ◽  
...  
Keyword(s):  
Vitamin D ◽  
Enzyme Activity ◽  
Ornithine Decarboxylase ◽  
Calcium Absorption ◽  
Duodenal Mucosa ◽  
Decarboxylase Activity ◽  
Absorption Mechanism ◽  
Deficient Diet ◽  
Ornithine Decarboxylase Activity ◽  
Hormone Administration

The effect of cholecalciferol and its metabolites on ornithine decarboxylase activity was investigated in the duodenal mucosa of vitamin D-deficient chicks. The duodenal ornithine decarboxylase activity decreased in animals fed a vitamin D-deficient diet and its retarded activity was increased dose-dependently by a single injection of cholecalciferol. Among various metabolites of cholecalciferol tested, 1 alpha, 25-dihydroxycholecalciferol [ 1 alpha, 25 (OH)2D3] was the most potent stimulator. Stimulation of the enzyme activity was detected as early as 2h after intravenous administration of 1 alpha, 25 (OH)2D3 and a maximal value was attained at 6 h. The maximal value was 27 times higher than the control. In addition, treatment with 1 alpha 25 (OH)2D3 affected the duodenal content of polyamines. The content of putrescine increased to a value of three times that of the control 6 h after the hormone administration. The spermidine content did not change appreciably. The enhancement of duodenal ornithine decarboxylase activity by 1 alpha, 25 (OH)2D3 occurred in parallel with the enhancement of calcium absorption, which was first detected 3 h after the hormone administration. The enhancement appeared to be tissue-specific. It was observed in every intestinal segment, but was highest in the duodenum. Enzyme activity in other tissues was not influenced appreciably by 1 alpha, 25 (OH)2D3. These results clearly indicate that the duodenal biosynthesis of polyamines is regulated by 1 alpha, 25 (OH)2D3, suggesting the possibility that duodenal ornithine decarboxylase may be involved in the calcium absorption mechanism.

Stimulatory signals from the central nervous system for ornithine decarboxylase activity in the rat duodenal mucosa

1995 ◽  
Vol 2 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Kazuma Fujimoto ◽  
Hidesuke Morita ◽  
Chika Matsunaga ◽  
Shin-ichi Ogata ◽  
Noriaki Furukawa ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ornithine Decarboxylase ◽  
Duodenal Mucosa ◽  
Decarboxylase Activity ◽  
Ornithine Decarboxylase Activity ◽  
The Central Nervous System

Ornithine Decarboxylase Activity in Cultured Endothelial Cells Stimulated by Serum, Thrombin and Serotonin

1978 ◽  
Vol 39 (02) ◽  
pp. 496-503 ◽  
Author(s):  
P A D’Amore ◽  
H B Hechtman ◽  
D Shepro
Keyword(s):  
Endothelial Cells ◽  
Ornithine Decarboxylase ◽  
Decarboxylase Activity ◽  
Aortic Endothelial Cells ◽  
Ornithine Decarboxylase Activity ◽  
Rate Limiting Step ◽  
Bovine Aortic Endothelial Cells ◽  
Limiting Step ◽  
Rate Limiting ◽  
Serum Serotonin

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.

scholarly journals ORNITHINE DECARBOXYLASE ACTIVITY AS A PROGNOSTIC MARKER FOR COLORECTAL CANCER

2007 ◽  
Vol 53 (1) ◽  
pp. 1-9 ◽  
Author(s):  
YUTAKA HOSHINO ◽  
SHINYA TERASHIMA ◽  
YASUSHI TERANISHI ◽  
MASANORI TERASHIMA ◽  
MICHIHIKO KOGURE ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Marker ◽  
Ornithine Decarboxylase ◽  
Decarboxylase Activity ◽  
Ornithine Decarboxylase Activity
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