Evaluation of the effectiveness of an ambulatory teaching/treatment programme for non-insulin dependent (type 2) diabetic patients

1995 ◽  
Vol 32 (3) ◽  
pp. 143-147 ◽  
Author(s):  
M. I. Domenech ◽  
D. Assad ◽  
M. E. Mazzei ◽  
P. Kronsbein ◽  
J. J. Gagliardino
2010 ◽  
Vol 13 (7) ◽  
pp. A286-A287
Author(s):  
B Font ◽  
J Galera ◽  
R Lahoz ◽  
G Gambús ◽  
Clemente JM González

Diabetes ◽  
2003 ◽  
Vol 52 (7) ◽  
pp. 1792-1798 ◽  
Author(s):  
C. Anderwald ◽  
G. Brabant ◽  
E. Bernroider ◽  
R. Horn ◽  
A. Brehm ◽  
...  

1993 ◽  
Vol 138 (3) ◽  
pp. 565-572 ◽  
Author(s):  
M. Tepel ◽  
S. Bauer ◽  
S. Husseini ◽  
A. Raffelsiefer ◽  
W. Zidek

ABSTRACT Cytosolic free sodium concentrations ([Na+]i) in intact platelets from 32 type 2 (non-insulin-dependent) diabetic patients and from 27 age- and sex-matched non-diabetic control subjects were measured with the novel sodium-sensitive fluorescent dye sodium-binding-benzofuran-isophthalate. [Na+]i was significantly higher in platelets from type 2 diabetic patients compared with control subjects (40·6 ± 2·4 vs 32·0 ± 2·0 mmol/l, means ± s.e.m., P<0·03). Both systolic and diastolic blood pressure were significantly elevated in diabetic patients compared with control subjects. Analysis of diabetic patients showed a significant association between [Na+]i and diastolic blood pressure (P =0·026). Stimulation of Na/H exchange by thrombin increased [Na+]i in both groups. After inhibition of Na/K/ATPase by ouabain (1 mmol/l), [Na+]i was significantly increased both in diabetic patients and non-diabetic subjects in a similar way (by 40·2 ± 7·3 and 31·7 ± 5·3 mmol/l respectively). It is concluded that increased [Na+]i in cells from type 2 diabetic patients may be related to hypertension. Journal of Endocrinology (1993) 138, 565–572


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