Hepatic 123I-insulin binding kinetics in non-insulin-dependent (Type 2) diabetic patients after i.v. bolus administration

1989 ◽  
Vol 15 (6) ◽  
pp. 292-295 ◽  
Author(s):  
M. Oolbekkink ◽  
R. J. Heine ◽  
W. den Hollander ◽  
J. J. P. Nauta ◽  
E. A. van der Veen
Keyword(s):  
Insulin Binding ◽  
Binding Kinetics ◽  
Diabetic Patients ◽  
Bolus Administration ◽  
Type 2 Diabetic Patients ◽  
Insulin Dependent ◽  
Type 2 Diabetic ◽  
Dependent Type

scholarly journals PDB18 EVALUATION OF CLINICAL INERTIA IN DIABETES CARE OF NON-INSULIN-DEPENDENT TYPE 2 DIABETIC PATIENTS

2010 ◽  
Vol 13 (7) ◽  
pp. A286-A287
Author(s):  
B Font ◽  
J Galera ◽  
R Lahoz ◽  
G Gambús ◽  
Clemente JM González
Keyword(s):  
Diabetes Care ◽  
Clinical Inertia ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Insulin Dependent ◽  
Type 2 Diabetic ◽  
Dependent Type

scholarly journals Insulin-Dependent Modulation of Plasma Ghrelin and Leptin Concentrations Is Less Pronounced in Type 2 Diabetic Patients

Diabetes ◽  
2003 ◽  
Vol 52 (7) ◽  
pp. 1792-1798 ◽  
Author(s):  
C. Anderwald ◽  
G. Brabant ◽  
E. Bernroider ◽  
R. Horn ◽  
A. Brehm ◽  
...  
Keyword(s):  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Insulin Dependent ◽  
Type 2 Diabetic

Increased cytosolic free sodium concentrations in platelets from type 2 (non-insulin-dependent) diabetic patients is associated with hypertension

1993 ◽  
Vol 138 (3) ◽  
pp. 565-572 ◽  
Author(s):  
M. Tepel ◽  
S. Bauer ◽  
S. Husseini ◽  
A. Raffelsiefer ◽  
W. Zidek
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Diabetic Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Control Subjects ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Type 2 Diabetic

ABSTRACT Cytosolic free sodium concentrations ([Na+]i) in intact platelets from 32 type 2 (non-insulin-dependent) diabetic patients and from 27 age- and sex-matched non-diabetic control subjects were measured with the novel sodium-sensitive fluorescent dye sodium-binding-benzofuran-isophthalate. [Na+]i was significantly higher in platelets from type 2 diabetic patients compared with control subjects (40·6 ± 2·4 vs 32·0 ± 2·0 mmol/l, means ± s.e.m., P<0·03). Both systolic and diastolic blood pressure were significantly elevated in diabetic patients compared with control subjects. Analysis of diabetic patients showed a significant association between [Na+]i and diastolic blood pressure (P =0·026). Stimulation of Na/H exchange by thrombin increased [Na+]i in both groups. After inhibition of Na/K/ATPase by ouabain (1 mmol/l), [Na+]i was significantly increased both in diabetic patients and non-diabetic subjects in a similar way (by 40·2 ± 7·3 and 31·7 ± 5·3 mmol/l respectively). It is concluded that increased [Na+]i in cells from type 2 diabetic patients may be related to hypertension. Journal of Endocrinology (1993) 138, 565–572

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