One-stage method of obtaining enriched fractions of rat brain neurons and glial cells

1980 ◽  
Vol 90 (5) ◽  
pp. 1625-1628
Author(s):  
A. A. Shpakov ◽  
V. I. Kuznetsova ◽  
Z. I. Savchenko
Keyword(s):  
Rat Brain ◽  
Glial Cells ◽  
Brain Neurons ◽  
One Stage ◽  
Rat Brain Neurons

Localization of pore-forming subunit of the ATP-sensitive K+-channel, Kir6.2, in rat brain neurons and glial cells

2002 ◽  
Vol 101 (1-2) ◽  
pp. 23-32 ◽  
Author(s):  
Ming Zhou ◽  
Osamu Tanaka ◽  
Masakazu Suzuki ◽  
Masaki Sekiguchi ◽  
Kuniaki Takata ◽  
...  
Keyword(s):  
Rat Brain ◽  
Glial Cells ◽  
K Channel ◽  
Brain Neurons ◽  
Rat Brain Neurons

Influence of Hemantane on Changes in Ca2+ and Na+ Caused by Activation of NMDA Channels in Cultured Rat Brain Neurons

2021 ◽  
Vol 15 (1) ◽  
pp. 8-17
Author(s):  
N. A. Voronina ◽  
O. Yu. Lisina ◽  
I. A. Krasilnikova ◽  
V. G. Kucheryanu ◽  
I. G. Kapitsa ◽  
...  
Keyword(s):  
Rat Brain ◽  
Brain Neurons ◽  
Nmda Channels ◽  
Rat Brain Neurons

Effects of Aged Garlic Extract on Rat Brain Neurons

2008 ◽  
pp. 153-161
Author(s):  
Hiroshi Saito ◽  
Toru Moriguchi ◽  
Yongxiang Zhang ◽  
Hiroshi Katsuki ◽  
Nobuyoshi Nishiyama
Keyword(s):  
Rat Brain ◽  
Garlic Extract ◽  
Aged Garlic Extract ◽  
Brain Neurons ◽  
Rat Brain Neurons ◽  
Aged Garlic

Decreased alpha 1-adrenergic receptor-mediated inositide hydrolysis in neurons from hypertensive rat brain

1986 ◽  
Vol 251 (2) ◽  
pp. C230-C237 ◽  
Author(s):  
J. B. Feldstein ◽  
R. A. Gonzales ◽  
S. P. Baker ◽  
C. Sumners ◽  
F. T. Crews ◽  
...  
Keyword(s):  
Rat Brain ◽  
Adrenergic Receptors ◽  
Inositol Phosphates ◽  
Inositol Phosphate ◽  
Specific Binding ◽  
Membrane Receptors ◽  
Neuronal Cultures ◽  
Brain Neurons ◽  
Neuronal Membranes ◽  
Rat Brain Neurons

The expression of alpha 1-adrenergic receptors and norepinephrine (NE)-stimulated hydrolysis of inositol phospholipid has been studied in neuronal cultures from the brains of normotensive (Wistar-Kyoto, WKY) and spontaneously hypertensive (SH) rats. Binding of 125I-2-[beta-(4-hydroxyphenyl)-ethyl-aminomethyl] tetralone (HEAT) to neuronal membranes was 68-85% specific and was rapid. Competition-inhibition experiments with various agonists and antagonists suggested that 125I-HEAT bound selectively to alpha 1-adrenergic receptors. Specific binding of 125I-HEAT to neuronal membranes from SH rat brain cultures was 30-45% higher compared with binding in WKY normotensive controls. This increase was attributed to an increase in the number of alpha 1-adrenergic receptors on SH rat brain neurons. Incubation of neuronal cultures of rat brain from both strains with NE resulted in a concentration-dependent stimulation of release of inositol phosphates, although neurons from SH rat brains were 40% less responsive compared with WKY controls. The decrease in responsiveness of SH rat brain neurons to NE, even though the alpha 1-adrenergic receptors are increased, does not appear to be due to a general defect in membrane receptors and postreceptor signal transduction mechanisms. This is because neither the number of muscarinic-cholinergic receptors nor the carbachol-stimulated release of inositol phosphates is different in neuronal cultures from the brains of SH rats compared with neuronal cultures from the brains of WKY rats. These observations suggest that the increased expression of alpha 1-adrenergic receptors does not parallel the receptor-mediated inositol phosphate hydrolysis in neuronal cultures from SH rat brain.

scholarly journals The serine racemase mRNA is predominantly expressed in rat brain neurons

2007 ◽  
Vol 70 (2) ◽  
pp. 127-134 ◽  
Author(s):  
Masanobu Yoshikawa ◽  
Naoko Takayasu ◽  
Atsushi Hashimoto ◽  
Yuichi Sato ◽  
Raita Tamaki ◽  
...  
Keyword(s):  
Rat Brain ◽  
Serine Racemase ◽  
Brain Neurons ◽  
Rat Brain Neurons
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