Analysis of neurochemical mechanisms of the psychotropic action of tuftsin and its analogs

1982 ◽  
Vol 93 (4) ◽  
pp. 452-456
Author(s):  
A. V. Val'dman ◽  
N. A. Bondarenko ◽  
V. A. Kamysheva ◽  
M. M. Kozlovskaya ◽  
V. N. Kalikhevich ◽  
...  
Keyword(s):  
Neurochemical Mechanisms ◽  
Psychotropic Action

Possible new neurochemical mechanisms of epilepsy

2017 ◽  
Vol 0 (2.88) ◽  
pp. 11-15
Author(s):  
A.S. Kharibegashvili ◽  
S.K. Yevtushenko ◽  
M.F. Ivanova
Keyword(s):  
Neurochemical Mechanisms

Combining transcranial brain stimulation and PET/SPECT molecular imaging

2021 ◽  
Author(s):  
Sang Soo Cho ◽  
Antonio P. Strafella
Keyword(s):  
Brain Stimulation ◽  
Single Photon ◽  
Photon Emission ◽  
Functional Magnetic Resonance ◽  
Single Photon Emission ◽  
Neurochemical Mechanisms ◽  
Brain Functions ◽  
Positron Emission ◽  
Transcranial Brain Stimulation ◽  
Plastic Changes

Transcranial brain stimulation (TMS) was introduced in 1985 by Barker and his colleagues. Since then, further improvements in technology have allowed additional applications and new stimulation protocols. In the last decade, while the use of TMS has expanded enormously in basic science as well as in the clinical scenario, the underlying neurophysiological or neurochemical mechanisms are still not fully understood. Positron emission tomography (PET) and single-photon emission computerized tomography (SPECT) are neuroimaging modalities utilized to investigate brain functions. In spite of their lower spatial and time resolution compared with functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), PET/SPECT have helped to elucidate some of the neurochemical mechanisms and neural plastic changes associated with TMS. In this chapter, we will provide an overview of these techniques, describing methodological details and application of TMS-PET/SPECT imaging in basic and clinical studies.

Features of the sensitivity of the central nervous system of the organism of experimental animals to the effects of certain psychotropic drugs and their combinations against the background of chronic alcohol intoxication in a chronopharmacological experiment

2020 ◽  
pp. 56-62
Author(s):  
E.V. Filippova
Keyword(s):  
Alcohol Intoxication ◽  
Laboratory Animals ◽  
Histological Structure ◽  
Chronic Alcohol ◽  
Behavioral Reactions ◽  
Experimental Animals ◽  
Chronic Alcohol Intoxication ◽  
Psychotropic Action ◽  
Adaptive Effect ◽  
The Central Nervous System

In a chronopharmacological experiment, the effect of two drugs with psychotropic action in combinations on the behavior of laboratory animals subjected to chronic alcohol intoxication was examined. Against the background of a deprimating agent, a decrease in the threshold of sensitivity to electrical irritation and the duration of an aggressive reaction was revealed; an increase in these indicators was established with a combination of a deprimating drug with an antioxidant. It has been shown that the antioxidant has a desynchronizing effect on the behavioral reactions of laboratory animals for two days, which indicates a pronounced adaptive effect. In the case of using combinations of a deprimating agent with an antioxidant, a decrease in the destruction of the histological structure of the myocardium against the background of chronic alcoholization was established.

Monoaminergic Mechanisms of Psychotropic Action of Short Peptides

1986 ◽  
pp. 203-238
Author(s):  
A. V. Valdman ◽  
M. M. Kozlovskaya ◽  
N. A. Bondarenko ◽  
V. V. Rojanetz ◽  
N. A. Avdulov ◽  
...  
Keyword(s):  
Short Peptides ◽  
Psychotropic Action ◽  
Monoaminergic Mechanisms
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