Effect of pineal peptide hormones on the functional activity of the human thyroidin Vitro. Effect of pineal peptides on the accumulation of cyclic nucleotides in the normal human thyroid and its secretory activity

1993 ◽  
Vol 116 (5) ◽  
pp. 1406-1408
Author(s):  
E. S. Rom-Bugoslavskaya ◽  
V. Yu. Gal'chinskaya ◽  
I. V. Komarova
Author(s):  
N. P. Dmitrieva

One of the most characteristic features of cancer cells is their ability to metastasia. It is suggested that the modifications of the structure and properties of cancer cells surfaces play the main role in this process. The present work was aimed at finding out what ultrastructural features apear in tumor in vivo which removal of individual cancer cells from the cell population can provide. For this purpose the cellular interactions in the normal human thyroid and cancer tumor of this gland electron microscopic were studied. The tissues were fixed in osmium tetroxide and were embedded in Araldite-Epon.In normal human thyroid the most common type of intercellular contacts was represented by simple junction formed by the parallelalignment of adjacent cell membranees leaving in between an intermembranes space 15-20 nm filled with electronlucid material (Fig. 1a). Sometimes in the basal part of cells dilatations of the intercellular space 40-50 nm wide were found (Fig. 1a). Here the cell surfaces may form single short microvilli.


1966 ◽  
Vol 53 (2) ◽  
pp. 297-302 ◽  
Author(s):  
Janine Bismuth ◽  
Marcel Rolland ◽  
Serge Lissitzky

ABSTRACT Amino acid composition of S19 thyroglobulin purified from three normal human thyroid glands, a hyperthyroid goiter, two hypothyroid familial goiters and a euthyroid goiter, has been determined. No significant differences in amino acid composition has been observed.


Nature ◽  
1971 ◽  
Vol 230 (5292) ◽  
pp. 334-335 ◽  
Author(s):  
STEVEN L. TEITELBAUM ◽  
KENNETH E. MOORE ◽  
WILLIAM SHIEBER

1952 ◽  
Vol 30 (3) ◽  
pp. 157-162
Author(s):  
A. DesMarais ◽  
J. Leblanc

Histochemical examination of adrenal glands of hypophysectomized rats given both ascorbic acid and ACTH showed an enlargement of the cortex and a decrease of sudanophilic substances, as compared to adrenals of hypophysectomized rats receiving ACTH alone. “In vitro” experiments on incubated slices of adrenal glands have shown that ascorbic acid and ACTH have a synergistic effect on the secretory activity of the cells of the adrenal cortex.


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