Strategy of the search for physiologically active substances according to their metabolites (survey)

1985 ◽  
Vol 19 (3) ◽  
pp. 163-170
Author(s):  
N. Ya. Golovenko ◽  
M. Yu. Totrova
Keyword(s):  
Physiologically Active Substances ◽  
Active Substances

scholarly journals Recent Advances in Quenchbody, a Fluorescent Immunosensor

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1223
Author(s):  
Jinhua Dong ◽  
Hiroshi Ueda
Keyword(s):  
Fluorescence Intensity ◽  
Fluorescent Dyes ◽  
Antibody Fragment ◽  
Disease Diagnosis ◽  
Disease Biomarkers ◽  
Highly Sensitive ◽  
Physiologically Active Substances ◽  
New Type ◽  
Antigen Antibody ◽  
Active Substances

The detection of viruses, disease biomarkers, physiologically active substances, drugs, and chemicals is of great significance in many areas of our lives. Immunodetection technology is based on the specificity and affinity of antigen–antibody reactions. Compared with other analytical methods such as liquid chromatography coupled with mass spectrometry, which requires a large and expensive instrument, immunodetection has the advantages of simplicity and good selectivity and is thus widely used in disease diagnosis and food/environmental monitoring. Quenchbody (Q-body), a new type of fluorescent immunosensor, is an antibody fragment labeled with fluorescent dyes. When the Q-body binds to its antigen, the fluorescence intensity increases. The detection of antigens by changes in fluorescence intensity is simple, easy to operate, and highly sensitive. This review comprehensively discusses the principle, construction, application, and current progress related to Q-bodies.

ChemInform Abstract: Progress in the Field of Physiologically Active Substances of Lanosterol Series

ChemInform ◽  
2010 ◽  
Vol 24 (30) ◽  
pp. no-no
Author(s):  
I. G. RESHETOVA ◽  
R. K. TKHAPER ◽  
A. V. KAMERNITSKII
Keyword(s):  
Physiologically Active Substances ◽  
Active Substances

scholarly journals FORMATION OF THE ROOT SYSTEM IN PHYLLOXERA TOLERANT GRAPE VARIETIES WITH FOLIAR APPLICATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES

2020 ◽  
Vol 3 (63) ◽  
pp. 121-134
Author(s):  
Ramidin Efendievich Kazakhmedov ◽  
◽  
Valeriy Semionovich Petrov ◽  
Bahtiyar Mutalibovich Saidov ◽  
Tamila Imiraslanovna Abdullayeva ◽  
...  
Keyword(s):  
Root System ◽  
Foliar Application ◽  
Physiologically Active Substances ◽  
Grape Varieties ◽  
Active Substances

Results of studying the influence of the treatment with the chemical mutagens on the Сallistephus chinensis (L.) Nees plants

2021 ◽  
pp. 202-212
Author(s):  
L.O. Shevel ◽  
◽  
A.I. Trokhymchuk ◽  
O.I. Rudnyk-Ivashchenko ◽  
◽  
...  
Keyword(s):  
Blue Flower ◽  
Mass Flowering ◽  
Chemical Mutagens ◽  
State Register ◽  
Long Term Storage ◽  
Dark Violet ◽  
Physiologically Active Substances ◽  
Term Storage ◽  
Active Substances

The authors present the influence of the treatment with the chemical mutagens on the Callistephus chinensis plants which was researched in 1998-2001. The samples originated by the studied cultivars open pollination were selected in the Experimental Farm “Novosilky” of the Institute of Horticulture of NAAS in 2002-2020. They are registered in the “data base” and included into the list of cvs of the collection of the seeds characteristics complex (Certificate of the registration of the collection of the plants genetic fund in Ukraine № 00230, November 1, 2016). The collection is registered in the National Centre of the Genetic Resources of the Plants of Ukraine and the seeds were transferred to the National Genetic Bank of the Plants of Ukraine for the long-term storage and for the use in the breeding work as new primary material. The plants of the five investigated varieties (Rubinovyie Zviozdy UT2300066), Oksana (UT2300046), Nizhnist (UT2300042), Yabluneva (UT2300081) and Prazdnichnaia (UT2300056) were treated with five physiologically active substances (DG-75, DG-72, DG-82, DG-468 and DG-608) in two concentrations during the mass flowering period. The results of the explorations showed the direct dependence of a bush diameter on its colouration. In the genotypes with the bright-red colour most of the families with diameter less than 30 cm were removed in all the generations. This also concerns the genotypes with the blue flower cluster colouration that were removed in the third generation. At the same time in the families with the wine-coloured flower clusters the plans with the bush diametr more than 30 cm prevail beginning from the second generation up the fifth one. According to the results of the researches all the studied genotypes can be combined into three groups concerning their response to the treatment by the mutagenes – sensitive (17.9 %), of the average sensitivity (62.5 %) and resistant (19.6 %). The striking exmples of the sensitive genotypes are the offsprings of the sample Rubinovyie Zviozdy which under the mutagens influence were characterized with the great variability as to several traits valuable for economy simultaneously. It is from this sample mother plant that the cultivars were selected as follows: Shokoladka (wine – coloured flower cluster), Oksamyt (dark-wine – coloured), and Sofia (dark-violet) which later on were entered into the State Register of the Plaint Cultivars Favourable for the Spread in Ukraine. In its turn, among those cvs the promise Callistephus chinensis (L.) Nees hybrid forms were selected, namely: C-125, C-116, C-233 and C-198-2 which have a complex of traits valuable for economy, including ornamentality (9.5-9.9 points), flower cluster diameter (10-14 cm) and Fusarium oxysporum resistance (8.8-9.0 points).

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