Improved method of oxidative cleavage of the dihydroxyacetone side chain in corticosteroids

1983 ◽  
Vol 17 (1) ◽  
pp. 73-74
Author(s):  
V. F. Shner ◽  
Z. V. Dybailo
1976 ◽  
Vol 157 (1) ◽  
pp. 207-210 ◽  
Author(s):  
E S Haslewood ◽  
G A D Haslewood

1. Thirty-eight steroids were tested as substrates for a 7 alpha-hydroxy steroid dehydrogenase preparation from a strain of Escherichia coli; an improved method of making the crude enzyme is described. 2. Steroids having a 7 alpha-hydroxyl group in the molecule were substrates except (a) when the 5 beta-cholan-24-oic acid side chain was shortened to less than four carbon atoms and (b) in certain cases when sulphate ester groups were present in the molecule. 3. For testing with the enzyme, a new specimen of 7 alpha-hydroxy-3,12-dioxo-5 beta-cholan-24-oic acid was made, which had properties different from those previously described.


Steroids ◽  
1997 ◽  
Vol 62 (6) ◽  
pp. 474-481 ◽  
Author(s):  
Takao Kurosawa ◽  
Masahiro Sato ◽  
Fumihiko Kikuchi ◽  
Takafumi Watanabe ◽  
Tetsuya Suga ◽  
...  

2000 ◽  
Vol 70 (6) ◽  
pp. 803-807 ◽  
Author(s):  
M. Helgert ◽  
B. Fleck ◽  
L. Wenke ◽  
S. Hvilsted ◽  
P.S. Ramanujam

Tetrahedron ◽  
2009 ◽  
Vol 65 (46) ◽  
pp. 9550-9556 ◽  
Author(s):  
Thor Håkon Krane Thvedt ◽  
Erik Fuglseth ◽  
Eirik Sundby ◽  
Bård Helge Hoff

Synthesis ◽  
1975 ◽  
Vol 1975 (12) ◽  
pp. 795-796 ◽  
Author(s):  
Jean-Marie BERNASSAU ◽  
Marcel FÉTIZON
Keyword(s):  

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