Observations on the fine structure of interdigitating cell sarcoma

1989 ◽  
Vol 414 (2) ◽  
pp. 121-128 ◽  
Author(s):  
Shigeo Nakamura ◽  
Ryoji Suzuki ◽  
Junpei Asai ◽  
Taizan Suchi
1992 ◽  
Vol 97 (1) ◽  
pp. 139-146 ◽  
Author(s):  
Mitsunori Yamakawa ◽  
Mikio Matsuda ◽  
Yutaka Imai ◽  
Shigeru Arai ◽  
Kohji Harada ◽  
...  

Cancer ◽  
1988 ◽  
Vol 61 (3) ◽  
pp. 562-568 ◽  
Author(s):  
Shigeo Nakamura ◽  
Kazuo Hara ◽  
Taizan Suchi ◽  
Masafumi Ito ◽  
Hiroshi Ikeda ◽  
...  

1991 ◽  
Vol 7 (5) ◽  
pp. 553-555 ◽  
Author(s):  
Shigeo Nakamura ◽  
Sadayuki Kaba ◽  
Takashi Koshikawa ◽  
Taizan Suchi ◽  
Soji Kurita

2008 ◽  
Vol 44 (5) ◽  
pp. 374-386 ◽  
Author(s):  
Shigeo Nakamura ◽  
Takashi Koshikawa ◽  
Kuniyoshi Kitoh ◽  
Atsuo Nakayama ◽  
Mitsunori Yarnakawa ◽  
...  

1991 ◽  
Vol 30 (6) ◽  
pp. 1136-1140
Author(s):  
Tokiko SHIMOJIMA ◽  
Chikako YAMADA ◽  
Mitsunori YAMAKAWA ◽  
Yutaka IMAI ◽  
Shigeru ARAI

1990 ◽  
Vol 29 (4) ◽  
pp. 522-525
Author(s):  
Shigeo NAKAMURA ◽  
Sadayuki KABA ◽  
Kuniyoshi KITO ◽  
Taizan SUCHI ◽  
Soji KURITA ◽  
...  

2005 ◽  
Vol 45 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Kunihiko Maeda ◽  
Tomoko Takahashi ◽  
Chihiro Saitoh ◽  
Keiko Watarai ◽  
Kiriko Wada ◽  
...  

1989 ◽  
Vol 415 (5) ◽  
pp. 447-457 ◽  
Author(s):  
Shigeo Nakamura ◽  
Taizan Suchi ◽  
Ryozi Suzuki ◽  
Norio Takagi ◽  
Kuniyoshi Kitoh ◽  
...  

Blood ◽  
2008 ◽  
Vol 111 (12) ◽  
pp. 5433-5439 ◽  
Author(s):  
Andrew L. Feldman ◽  
Daniel A. Arber ◽  
Stefania Pittaluga ◽  
Antonio Martinez ◽  
Jerome S. Burke ◽  
...  

Abstract Rare cases of histiocytic and dendritic cell (H/DC) neoplasms have been reported in patients with follicular lymphoma (FL), but the biologic relationship between the 2 neoplasms is unknown. We studied 8 patients with both FL and H/DC neoplasms using immunohistochemistry, fluorescence in situ hybridization (FISH) for t(14;18), and polymerase chain reaction (PCR)/sequencing of BCL2 and IGH rearrangements. There were 5 men and 3 women (median age, 59 years). All cases of FL were positive for t(14;18). The H/DC tumors included 7 histiocytic sarcomas, 5 of which showed evidence of dendritic differentiation, and 1 interdigitating cell sarcoma. Five H/DC tumors were metachronous, following FL by 2 months to 12 years; tumors were synchronous in 3. All 8 H/DC tumors showed presence of the t(14;18) either by FISH, or in 2 cases by PCR with the major breakpoint region (MBR) probe. PCR and sequencing identified identical IGH gene rearrangements or BCL2 gene breakpoints in all patients tested. All H/DC tumors lacked PAX5, and up-regulation of CEBPβ and PU.1 was seen in all cases tested. These results provide evidence for a common clonal origin of FL and H/DC neoplasms when occurring in the same patient, and suggest that lineage plasticity may occur in mature lymphoid neoplasms.


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