Pharmacokinetics of high-dose etoposide after short-term infusion

1992 ◽  
Vol 29 (4) ◽  
pp. 316-320 ◽  
Author(s):  
P. K�hl ◽  
H. K�ppler ◽  
L. Schmidt ◽  
H. W. Fritsch ◽  
J. Holz ◽  
...  
Keyword(s):  
High Dose ◽  
Short Term

The effect of high‐dose, short‐term caffeine intake on the renal clearance of calcium, sodium and creatinine in healthy adults

2021 ◽  
Author(s):  
Stephanie E. Reuter ◽  
Hayley B. Schultz ◽  
Michael B. Ward ◽  
Crystal L. Grant ◽  
Gemma M. Paech ◽  
...  
Keyword(s):  
Renal Clearance ◽  
Healthy Adults ◽  
Caffeine Intake ◽  
High Dose ◽  
Short Term

Short-term corticosteroid therapy in childhood asthma

1976 ◽  
Vol 14 (8) ◽  
pp. 31-32
Keyword(s):  
Sodium Cromoglycate ◽  
Corticosteroid Therapy ◽  
Childhood Asthma ◽  
Maintenance Treatment ◽  
High Dose ◽  
Severe Exacerbation ◽  
Short Term ◽  
At Home

Attacks of asthma in most children are relatively mild, but in a few they are severe and potentially fatal.1 The severity of attacks can be reduced by β-adrenoceptor stimulants, theophylline compounds and sodium cromoglycate, but when these are not effective it may be necessary to give a corticosteroid continuously. For those children who develop a severe exacerbation despite maintenance treatment, or those who get infrequent but often severe attacks that do not respond to bronchodilators, a short high-dose course of a corticosteroid can be given, and many practitioners choose to give this to their patients at home.2 However since no trials of such treatment have been performed the benefit remains unproven.

Analysis of acute naproxen administration on memory in young adults: A randomized, double-blind, placebo-controlled study

2017 ◽  
Vol 31 (10) ◽  
pp. 1374-1376
Author(s):  
Jack H Wilson ◽  
Amy H Criss ◽  
Sean A Spangler ◽  
Katherine Walukevich ◽  
Sandra Hewett
Keyword(s):  
Young Adults ◽  
Healthy Adult ◽  
Adult Population ◽  
Critical Role ◽  
Random Order ◽  
Controlled Study ◽  
High Dose ◽  
Short Term ◽  
Double Blind ◽  
Inflammatory Drugs

Nonsteroidal anti-inflammatory drugs work by non-selectively inhibiting cyclooxygenase enzymes. Evidence indicates that metabolites of the cyclooxygenase pathway play a critical role in the process of learning and memory. We evaluated whether acute naproxen treatment impairs short-term working memory, episodic memory, or semantic memory in a young, healthy adult population. Participants received a single dose of placebo or naproxen (750 mg) in random order separated by 7–10 days. Two hours following administration, participants completed five memory tasks. The administration of acute high-dose naproxen had no effect on memory in healthy young adults.

Short-term, High-dose Methotrexate Therapy in a Case of Severe Psoriatic Arthritis

Rheumatology ◽  
1988 ◽  
Vol 27 (2) ◽  
pp. 160-162 ◽  
Author(s):  
E. EECKHOUT ◽  
E. SUYS ◽  
P. BUYDENS ◽  
S. VAN BELLE ◽  
L. A. VERBRUGGEN
Keyword(s):  
Psoriatic Arthritis ◽  
Methotrexate Therapy ◽  
High Dose ◽  
High Dose Methotrexate ◽  
Short Term ◽  
Dose Methotrexate
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