Development and validation of a sensitive solid-phase-extraction and high-performance liquid chromatography assay for the bioreductive agent tirapazamine and its major metabolites in mouse and human plasma for pharmacokinetically guided dose escalation

1995 ◽  
Vol 36 (3) ◽  
pp. 266-270 ◽  
Author(s):  
Hernani Robin ◽  
Suresh Senan ◽  
Paul Workman ◽  
Martin A. Graham
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Human Plasma ◽  
Dose Escalation ◽  
High Performance ◽  
Solid Phase ◽  
Phase Extraction ◽  
Development And Validation

scholarly journals Trace determination of chlorpheniramine in human plasma using magnetic dispersive solid-phase extraction based on a graphene oxide/Fe3O4@polythionine nanocomposite combined with high-performance liquid chromatography

RSC Advances ◽  
2017 ◽  
Vol 7 (84) ◽  
pp. 53210-53218 ◽  
Author(s):  
Maryam Ahmadi Daryakenary ◽  
Mohsen Zeeb
Keyword(s):  
High Performance Liquid Chromatography ◽  
Graphene Oxide ◽  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Human Plasma ◽  
High Performance ◽  
Solid Phase ◽  
Phase Extraction ◽  
Dispersive Solid Phase Extraction

Graphene oxide/Fe3O4@polythionine (GO/Fe3O4@PTh) nanocomposite was fabricated for magnetic dispersive solid-phase extraction and high-performance liquid chromatography-ultraviolent detection (HPLC) of chlorpheniramine in human plasma.

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