Inhibition of corn spermidine oxidase by acridine derivatives

1973 ◽  
Vol 60 (3) ◽  
pp. 155-156 ◽  
Author(s):  
Y. Suzuki ◽  
E. Hirasawa
Keyword(s):  
Acridine Derivatives ◽  
Spermidine Oxidase

Cu-Catalyzed Cascade Reaction of Isoxazoles with Diaryliodonium Salts for the Synthesis of Acridines

2020 ◽  
Vol 17 (12) ◽  
pp. 944-950
Author(s):  
Shangrong Zhu ◽  
Xuechen Lu ◽  
Qiuneng Xu ◽  
Jian Li ◽  
Shenghu Yan
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Acridine Derivatives ◽  
Diaryliodonium Salts

A straightforward and efficient synthesis of acridine derivatives via a copper-catalyzed cascade reaction among isoxazoles and diaryliodonium salts is achieved. Various mono-, multi-substituted and 9-substituted acridine derivatives could be obtained in moderate to good yields. The process has gone through tandem double arylation and Friedel-Crafts reactions.

9-Substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships

1995 ◽  
Vol 38 (17) ◽  
pp. 3226-3235 ◽  
Author(s):  
Tsann-Long Su ◽  
Ting-Chao Chou ◽  
Joong Young Kim ◽  
Jai-Tung Huang ◽  
Grazyna Ciszewska ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Half Life ◽  
Structure Activity Relationships ◽  
Acridine Derivatives ◽  
Structure Activity
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