Effect of hind-limb immobilization on contractile and histochemical properties of skeletal muscle

1973 ◽  
Vol 342 (3) ◽  
pp. 231-238 ◽  
Author(s):  
F. W. Booth ◽  
J. R. Kelso
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Limb Immobilization

scholarly journals Chronic Alcohol Dysregulates Skeletal Muscle Myogenic Gene Expression after Hind Limb Immobilization in Female Rats

Biomolecules ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 441
Author(s):  
Danielle E. Levitt ◽  
Alice Y. Yeh ◽  
Matthew J. Prendergast ◽  
Ronald G. Budnar, Jr. ◽  
Katherine A. Adler ◽  
...  
Keyword(s):  
Gene Expression ◽  
Skeletal Muscle ◽  
Muscle Regeneration ◽  
Hind Limb ◽  
Female Rats ◽  
Skeletal Muscle Regeneration ◽  
Skeletal Muscle Atrophy ◽  
Expression Of Genes ◽  
Risk Factors For Falls ◽  
Limb Immobilization

Alcohol use and aging are risk factors for falls requiring immobilization and leading to skeletal muscle atrophy. Skeletal muscle regeneration is integral to post-immobilization recovery. This study aimed to elucidate the effects of alcohol and ovarian hormone loss on the expression of genes implicated in muscle regeneration. Three-month-old female rats received an ovariectomy or a sham surgery, consumed an alcohol-containing or control diet for 10 weeks, were subjected to unilateral hind limb immobilization for seven days, and finally were allowed a three (3d)- or 14 (14d)-day recovery. Immobilization decreased the quadriceps weight at 3d and 14d, and alcohol decreased the quadriceps weight at 14d in the nonimmobilized hind limb (NI). At 3d, alcohol decreased gene expression of myoblast determination protein (MyoD) in the immobilized hind limb (IMM) and myocyte enhancer factor (Mef)2C and tumor necrosis factor (TNF)α in NI, and ovariectomy increased MyoD and decreased TNFα expression in NI. At 14d, alcohol increased the gene expression of Mef2C, MyoD, TNFα, and transforming growth factor (TFG)β in IMM and decreased monocyte chemoattractant protein (MCP)1 expression in NI; ovariectomy increased TNFα expression in NI, and alcohol and ovariectomy together increased Mef2C expression in NI. Despite increased TGFβ expression, there was no concomitant alcohol-mediated increase in collagen in IMM at 14d. Overall, these data indicate that alcohol dysregulated the post-immobilization alteration in the expression of genes implicated in regeneration. Whether alcohol-mediated molecular changes correspond with post-immobilization functional alterations remains to be determined.

Glycogen Metabolism and Glucose Uptake Rate of the Skeletal Muscle after Hind - limb Immobilization in Rats

1990 ◽  
Vol 25 (3) ◽  
pp. 641
Author(s):  
Joo Chul Ihn ◽  
Jong chul Ahn ◽  
Myun Whan Ahn ◽  
Chun Bae Jeon ◽  
Suck Kang Lee ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Glucose Uptake ◽  
Uptake Rate ◽  
Hind Limb ◽  
Glycogen Metabolism ◽  
Glucose Uptake Rate ◽  
Limb Immobilization

Alteration of spinal cord IGF-I receptors and skeletal muscle IGF-I after hind-limb immobilization in the rat

Neuroreport ◽  
1999 ◽  
Vol 10 (6) ◽  
pp. 1195-1199 ◽  
Author(s):  
Isam A. Suliman ◽  
J Urban Lindgren ◽  
Per-Göran Gillberg ◽  
Adlan M. Elhassan ◽  
Christine Monneron ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Spinal Cord ◽  
Hind Limb ◽  
Igf I ◽  
Limb Immobilization

scholarly journals The Ubr2 gene is expressed in skeletal muscle atrophying as a result of hind limb suspension, but not Merg1a expression alone

2014 ◽  
Vol 24 (3) ◽  
Author(s):  
Gregory H. Hockerman ◽  
Nicole M. Dethrow ◽  
Sohaib Hameed ◽  
Maureen Doran ◽  
Christine Jaeger ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Hind Limb Suspension

scholarly journals Apolipoprotein E–/– mice have delayed skeletal muscle healing after hind limb ischemia–reperfusion

2008 ◽  
Vol 48 (3) ◽  
pp. 701-708 ◽  
Author(s):  
Jeanwan Kang ◽  
Hassan Albadawi ◽  
Virendra I. Patel ◽  
Thomas A. Abbruzzese ◽  
Jin-Hyung Yoo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Apolipoprotein E ◽  
Hind Limb ◽  
Ischemia Reperfusion ◽  
Limb Ischemia ◽  
Hind Limb Ischemia

scholarly journals Slow- and fast-twitch rat hind limb skeletal muscle phenotypes 8 months after spinal cord transection and olfactory ensheathing glia transplantation

2008 ◽  
Vol 586 (10) ◽  
pp. 2593-2610 ◽  
Author(s):  
Pilar Negredo ◽  
José-Luis L. Rivero ◽  
Beatriz González ◽  
Almudena Ramón-Cueto ◽  
Rafael Manso
Keyword(s):  
Skeletal Muscle ◽  
Spinal Cord ◽  
Hind Limb ◽  
Spinal Cord Transection ◽  
Olfactory Ensheathing Glia ◽  
Fast Twitch

scholarly journals Mouse Hind Limb Skeletal Muscle Functional Adaptation in a Simulated Fine Branch Arboreal Habitat

2018 ◽  
Vol 301 (3) ◽  
pp. 434-440 ◽  
Author(s):  
Joseph E. Rupert ◽  
J. Ethan Joll ◽  
Wiaam Y. Elkhatib ◽  
Jason M. Organ
Keyword(s):  
Skeletal Muscle ◽  
Hind Limb ◽  
Functional Adaptation ◽  
Arboreal Habitat ◽  
Fine Branch
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