Effects of cimetidine on adenylate cyclase activity of guinea pig gastric mucosa stimulated by histamine, sodium fluoride and 5?-guanylylimidodiphosphate

1976 ◽  
Vol 294 (2) ◽  
pp. 209-211 ◽  
Author(s):  
P. Anttila ◽  
E. Westermann
Keyword(s):  
Gastric Mucosa ◽  
Adenylate Cyclase ◽  
Guinea Pig ◽  
Sodium Fluoride ◽  
Cyclase Activity ◽  
Adenylate Cyclase Activity

Evaluation of novel compounds interacting with H2-histamine receptors: Effect on histamine-sensitive adenylate cyclase activity in guinea-pig gastric mucosa

1985 ◽  
Vol 16 (5) ◽  
pp. 291-294 ◽  
Author(s):  
Rosella Micheletti ◽  
Daniela Oliva ◽  
Pietro Belfiore ◽  
Antonio Giachetti ◽  
Simonetta Nicosia
Keyword(s):  
Gastric Mucosa ◽  
Adenylate Cyclase ◽  
Guinea Pig ◽  
Histamine Receptors ◽  
Cyclase Activity ◽  
Adenylate Cyclase Activity

Effect of histamine on canine gastric mucosal adenylate cyclase.

1977 ◽  
Vol 232 (1) ◽  
pp. E35
Author(s):  
R R Dozois ◽  
A Wollin ◽  
R D Rettmann ◽  
T P Dousa
Keyword(s):  
Gastric Mucosa ◽  
Cyclic Amp ◽  
Adenylate Cyclase ◽  
Cyclase Activity ◽  
Adenylate Cyclase Activity ◽  
Antral Mucosa ◽  
Fundic Mucosa ◽  
H2 Receptors ◽  
Dose Dependent ◽  
Stimulation Of

The effects of histamine, Nalpha-dimethylhistamine, 4,5-methylhistamine, Ntau-methylhistamine, pentagastrin, carbachol, and NaF on the adenylate cyclase activity from canine gastric mucosa were investigated in cell-free preparations. In gastric fundic mucosa, histamine (10(-4) M), Nalpha-dimethylhistamine (10(-4) M), 4,5-methylhistamine (10(-4 M), and NaF (10)-2) M) significantly (P less than 0.001) increased adenylate cyclase activity (means+/-SE) by 44.7+/-6.6, 49.4+/-6.7, 34.0+/-6.4, and 572.0+/-100%, respectively, above basal activity. The effect of histamine and Na-dimethyl histamine was dose-dependent. In contrast, other tested agents failed to stimulate the formation of cyclic AMP in gastric fundic mucosa. Metiamide (10(-4) M) blocked the stimulation of fundic mucosa adenylate cyclase by histamine and Nalpha-dimethylhistamine, without significantly altering basal and NaF-induced adenylate cyclase activity. Histamine, however, did not stimulate the adenylate cyclase activity from the gastric antral mucosa. The findings support the proposal that the canine gastric acid response to histamine may be mediated by cyclic AMP formed in response to stimulation of histamine H2-receptors.

Effects of PHI on vasoactive intestinal peptide receptors and adenylate cyclase activity in lung membranes. A comparison in man, rat, mouse and guinea pig

1982 ◽  
Vol 4 (5) ◽  
pp. 241-250 ◽  
Author(s):  
Patrick Robberecht ◽  
Kazuhiko Tatemoto ◽  
Pierre Chatelain ◽  
Magali Waelbroeck ◽  
Myriam Delhaye ◽  
...  
Keyword(s):  
Adenylate Cyclase ◽  
Guinea Pig ◽  
Vasoactive Intestinal Peptide ◽  
Cyclase Activity ◽  
Adenylate Cyclase Activity ◽  
Peptide Receptors

Cytochemical demonstration of Adenylate cyclase activity in basal compartment of Guinea pig testis

1983 ◽  
Vol 50 (1-2) ◽  
pp. 105-108
Author(s):  
Rita Pascolini ◽  
Daniela Vagnetti ◽  
Marinella Marinelli ◽  
Sergio Lorvik
Keyword(s):  
Adenylate Cyclase ◽  
Guinea Pig ◽  
Cyclase Activity ◽  
Adenylate Cyclase Activity ◽  
Cytochemical Demonstration
Sign in / Sign up

Export Citation Format

Share Document