High-resolution scanning-densitometry of photographic negatives of human chromosomes

1977 ◽  
Vol 51 (4) ◽  
pp. 269-291 ◽  
Author(s):  
M. van der Ploeg ◽  
A. M. Vossepoel ◽  
F. Th. Bosman ◽  
P. van Duijn
Keyword(s):  
High Resolution ◽  
Human Chromosomes ◽  
Scanning Densitometry

High resolution analysis and differential condensation in RBA-banded human chromosomes

1981 ◽  
Vol 59 (3) ◽  
Author(s):  
E. Schollmayer ◽  
D. Sch�fer ◽  
B. Frisch ◽  
E. Schleiermacher
Keyword(s):  
High Resolution ◽  
Human Chromosomes ◽  
High Resolution Analysis ◽  
Resolution Analysis

High resolution of human chromosomes

Science ◽  
1976 ◽  
Vol 191 (4233) ◽  
pp. 1268-1270 ◽  
Author(s):  
J. Yunis
Keyword(s):  
High Resolution ◽  
Human Chromosomes

High-resolution scanning-densitometry of photographic negatives of human metaphase chromosomes

1974 ◽  
Vol 42 (1) ◽  
pp. 9-29 ◽  
Author(s):  
M. van der Ploeg ◽  
P. van Duijn ◽  
J. S. Ploem
Keyword(s):  
High Resolution ◽  
Metaphase Chromosomes ◽  
Scanning Densitometry

High-resolution scanning-densitometry of photographic negatives of human metaphase chromosomes

1974 ◽  
Vol 42 (1) ◽  
pp. 31-46 ◽  
Author(s):  
M. van der Ploeg ◽  
P. van Duijn ◽  
J. S. Ploem
Keyword(s):  
High Resolution ◽  
Metaphase Chromosomes ◽  
Scanning Densitometry

G-banding patterns of high-resolution human chromosomes 6?22, X, and Y

1979 ◽  
Vol 49 (3) ◽  
pp. 291-306 ◽  
Author(s):  
J. J. Yunis ◽  
D. W. Ball ◽  
J. R. Sawyer
Keyword(s):  
High Resolution ◽  
Human Chromosomes ◽  
Banding Patterns

scholarly journals Correlative high-resolution morphologic analysis of the three-dimensional organization of human chromosomes

Scanning ◽  
2006 ◽  
Vol 22 (5) ◽  
pp. 273-281 ◽  
Author(s):  
Pietro Gobbi ◽  
Stefan Thalhammer ◽  
Mirella Falconi ◽  
Robert W. Stark ◽  
Wolfgang M. Heckl ◽  
...  
Keyword(s):  
High Resolution ◽  
Three Dimensional ◽  
Human Chromosomes ◽  
Morphologic Analysis

A high-resolution comparative map between pig chromosome 17 and human chromosomes 4, 8, and 20: Identification of synteny breakpoints

Genomics ◽  
2005 ◽  
Vol 86 (4) ◽  
pp. 405-413 ◽  
Author(s):  
Yvette Lahbib-Mansais ◽  
Peter Karlskov-Mortensen ◽  
Florence Mompart ◽  
Denis Milan ◽  
Claus B. Jørgensen ◽  
...  
Keyword(s):  
High Resolution ◽  
Chromosome 17 ◽  
Human Chromosomes ◽  
Comparative Map

Chromatin ofh regions of human chromosomes at high resolution

1984 ◽  
Vol 40 (8) ◽  
pp. 878-879 ◽  
Author(s):  
R. S. Verma ◽  
J. Rodriguez ◽  
H. Dosik
Keyword(s):  
High Resolution ◽  
Human Chromosomes

Ideograms of high-resolution trypsin-Giemsa banded human chromosomes

1978 ◽  
Vol 22 (1-6) ◽  
pp. 668-671
Author(s):  
N. Oliver ◽  
U. Francke
Keyword(s):  
High Resolution ◽  
Human Chromosomes

scholarly journals MICROFLUOROMETRIC ANALYSIS OF DEOXYRIBONUCLEIC ACID REPLICATION KINETICS AND SISTER CHROMATID EXCHANGES IN HUMAN CHROMOSOMES

1974 ◽  
Vol 22 (7) ◽  
pp. 478-491 ◽  
Author(s):  
SAMUEL A. LATT
Keyword(s):  
High Resolution ◽  
Dna Synthesis ◽  
Sister Chromatid ◽  
Deoxyribonucleic Acid ◽  
Sister Chromatid Exchanges ◽  
Human Chromosomes ◽  
Metaphase Chromosomes ◽  
Banding Patterns ◽  
Human Leukocytes ◽  
Chromatid Exchanges

Fluorescence of the dye 33258 Hoechst, when bound to chromosomes, is partially quenched by the incorporation of 5-bromodeoxyuridine into chromosomal deoxyribonucleic acid (DNA). This effect allows microfluorometric analysis of DNA synthesis. Metaphase chromosomes from cultured human leukocytes which have incorporated 5-bromodeoxyuridine for a portion of the DNA synthesis period exhibit reduced 33258 Hoechst fluorescence in 5-bromodeoxyuridine-containing regions. Regions synthesizing DNA during a particular interval can thus be highlighted by the appropriate protocol of 5-bromodeoxyuridine administration. Chromosomes from cells which have replicated twice in medium containing 5-bromodeoxyuridine exhibit one brightly and one dully fluorescing chromatid, reflecting incorporation of 5-bromodeoxyuridine into one or two chains of chromatid DNA, respectively. Sister chromatid exchanges, evident as sharply demarcated reciprocal alterations in fluorescence along chromosomes, can be located relative to quinacrine banding patterns. This fluorometric approach should be useful in many instances as a convenient, high resolution alternative to autoradiography.

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