Quantitative histological and immunohistochemical findings in jejunal biopsy specimens in giardiasis

1981 ◽  
Vol 393 (2) ◽  
pp. 145-151 ◽  
Author(s):  
P. C. M. Rosekrans ◽  
J. Lindeman ◽  
C. J. L. M. Meijer
Keyword(s):  
Jejunal Biopsy ◽  
Biopsy Specimens

scholarly journals Photographing jejunal biopsy specimens.

BMJ ◽  
1967 ◽  
Vol 1 (5534) ◽  
pp. 237-238
Author(s):  
M. Taylor
Keyword(s):  
Jejunal Biopsy ◽  
Biopsy Specimens

Subcellular Fractionation Studies of the Intestinal Mucosa in Congenital Sucrase—Isomaltase Deficiency

1979 ◽  
Vol 57 (2) ◽  
pp. 181-185 ◽  
Author(s):  
B. T. Cooper ◽  
D. C. A. Candy ◽  
J. T. Harries ◽  
T. J. Peters
Keyword(s):  
Electron Microscopy ◽  
Intestinal Mucosa ◽  
Brush Border ◽  
Enzyme Activities ◽  
Subcellular Fractionation ◽  
The Other ◽  
Marker Enzyme ◽  
Jejunal Biopsy ◽  
Biopsy Specimens ◽  
Highly Sensitive

1. Jejunal biopsy specimens from three children with congenital sucrase—isomaltase deficiency were assayed for disaccharidase activity and were subjected to analytical subcellular fractionation with enzymic microanalysis. 2. By use of the highly sensitive fluorigenic modification of the disaccharidase assay, brush-border sucrase and isomaltase activities were depressed but nevertheless detectable in each child. 3. Apart from the expected decrease in brush-border α-glucosidase activity, the other enterocyte marker-enzyme activities were normal. 4. There were no abnormalities in the enterocytes of any child on analytical subcellular fractionation or on electron microscopy.

Mycological Study of Jejunal Biopsy Specimens from Patients with Tropical Sprue *

1965 ◽  
Vol 14 (6) ◽  
pp. 1066-1068 ◽  
Author(s):  
Virginia L. Swanson ◽  
Leanor D. Haley ◽  
Munsey S. Wheby
Keyword(s):  
Tropical Sprue ◽  
Jejunal Biopsy ◽  
Biopsy Specimens

scholarly journals Use of electron microscopy in examination of faeces and rectal and jejunal biopsy specimens.

1991 ◽  
Vol 44 (4) ◽  
pp. 313-316 ◽  
Author(s):  
G M Connolly ◽  
D S Ellis ◽  
J E Williams ◽  
G Tovey ◽  
B G Gazzard
Keyword(s):  
Electron Microscopy ◽  
Jejunal Biopsy ◽  
Biopsy Specimens

Quantification of Immune Cell Populations in the Lamina Propria of Equine Jejunal Biopsy Specimens

2005 ◽  
Vol 132 (1) ◽  
pp. 90-95 ◽  
Author(s):  
M. Packer ◽  
J.C. Patterson-Kane ◽  
K.C. Smith ◽  
A.E. Durham
Keyword(s):  
Lamina Propria ◽  
Immune Cell ◽  
Cell Populations ◽  
Jejunal Biopsy ◽  
Biopsy Specimens

DISSECTING-MICROSCOPE APPEARANCES OF JEJUNAL BIOPSY SPECIMENS FROM PATIENTS WITH " IDIOPATHIC STEATORRHŒA"

The Lancet ◽  
1961 ◽  
Vol 277 (7168) ◽  
pp. 81-83 ◽  
Author(s):  
R. Holmes ◽  
D.O'B. Hourihane ◽  
C.C. Booth
Keyword(s):  
Jejunal Biopsy ◽  
Biopsy Specimens

Analytical Subcellular Fractionation of Jejunal Biopsy Specimens: Enzyme Activities, Organelle Pathology and Response to Gluten Withdrawal in Patients with Coeliac Disease

1978 ◽  
Vol 55 (3) ◽  
pp. 285-292 ◽  
Author(s):  
T. J. Peters ◽  
P. E. Jones ◽  
G. Wells
Keyword(s):  
Endoplasmic Reticulum ◽  
Coeliac Disease ◽  
Brush Border ◽  
Enzyme Activities ◽  
Subcellular Fractionation ◽  
Density Gradients ◽  
Marker Enzymes ◽  
Jejunal Biopsy ◽  
Essentially Normal ◽  
Biopsy Specimens

1. Portions of jejunal biopsy specimens from patients with coeliac disease were homogenized in isotonic sucrose solution and subjected to analytical subcellular fractionation by sucrose-density-gradient centrifugation. 2. The activities and distribution of marker enzymes for the principal subcellular organelles were determined by highly sensitive enzymic micro-assays employing fluorigenic and radiolabelled substrates. 3. In untreated coeliac disease the brush border showed decreased activities of five marker enzymes, which were reduced to up to one-eighth of control values. On sucrose density gradients the distinct brush-border peak at density 1.21 was replaced by a broad peak at density 1.16. 4. Two out of three lysosomal enzymes showed increased activities and there was evidence of enhanced fragility of both lysosomes and peroxisomes. 5. There were reduced activities of both mitochondrial and cytosol malate dehydrogenase, with increased activities of cytosol lactate dehydrogenase. 6. The endoplasmic reticulum and basal-lateral membranes were relatively unaffected except that the equilibrium densities were slightly increased and decreased respectively. 7. The patients were treated by gluten withdrawal and subsequent biopsies examined as above. Biopsies from patients treated for 2–4 weeks and who had not yet achieved a morphological improvement showed a partial return to normal of the pathological organelles. 8. Treated patients with partial villus atrophy showed progressively improved enzyme activities and a partial reappearance of the brush-border peak on the sucrose density gradients. 9. Patients whose intestinal mucosa had returned to morphological normality after prolonged gluten withdrawal showed a persistent defect in the brush-border enzyme activities. This was particularly striking for β-glucosidase, which was persistently deficient from the brush-border although approximately one-third of the total activity of this enzyme is normally found in this organelle. 10. The properties and enzyme activities of lysosomes, peroxisomes, endoplasmic reticulum, mitochondria and cytosol were essentially normal in the biopsies from fully treated patients.

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