A highly homologous T-cell receptor ?-chain variable region is expressed in mouse and human T cells

1985 ◽  
Vol 21 (4) ◽  
pp. 403-406 ◽  
Author(s):  
Augustinus Rinaldy ◽  
R. Bruce Wallace ◽  
Markus M. Simon ◽  
Andrea Becker ◽  
J�rg T. Epplen
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Variable Region ◽  
Cell Receptor ◽  
Human T Cells ◽  
Receptor Chain

Human ??T-Cells in the Epithelium of the Gut and in the Inflamed Synovial Tissue Preferentially Express the V?8 T-Cell Receptor Chain

1995 ◽  
Vol 756 (1 T-Cell Recept) ◽  
pp. 406-409 ◽  
Author(s):  
KALLE SÖDERSTRÖM ◽  
ANDERS BUCHT ◽  
EVA HALAPI ◽  
CARINA LUNDQVIST ◽  
ALVAR GRÖNBERG ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Synovial Tissue ◽  
Cell Receptor ◽  
Human T Cells ◽  
Receptor Chain

scholarly journals Characterization of human T cells reactive with the Mycoplasma arthritidis-derived superantigen (MAM): generation of a monoclonal antibody against V beta 17, the T cell receptor gene product expressed by a large fraction of MAM-reactive human T cells.

1991 ◽  
Vol 174 (4) ◽  
pp. 891-900 ◽  
Author(s):  
S M Friedman ◽  
M K Crow ◽  
J R Tumang ◽  
M Tumang ◽  
Y Q Xu ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Cell Activity ◽  
Cell Receptor ◽  
Cytotoxic T Cell ◽  
Mycoplasma Arthritidis ◽  
Human T Cells

While all known microbial superantigens are mitogenic for human peripheral blood lymphocytes (PBL), the functional response induced by Mycoplasma arthritidis-derived superantigen (MAM) is unique in that MAM stimulation of PBL consistently results in T cell-dependent B cell activation characterized by polyclonal IgM and IgG production. These immunostimulatory effects of MAM on the humoral arm of the human immune system warranted a more precise characterization of MAM-reactive human T cells. Using an uncloned MAM reactive human T cell line as immunogen, we have generated a monoclonal antibody (mAb) (termed C1) specific for the T cell receptor V beta gene expressed by the major fraction of MAM-reactive human T cells, V beta 17. In addition, a V beta 17- MAM-reactive T cell population exists, assessed by MAM, induced T cell proliferation and cytotoxic T cell activity. mAb C1 will be useful in characterizing the functional properties of V beta 17+ T cells and their potential role in autoimmune disease.

Expression of T-cell receptor α and β variable genes in normal and malignant human T cells

1993 ◽  
Vol 84 (1) ◽  
pp. 39-48 ◽  
Author(s):  
Huaizhong Hu ◽  
Màrio Rui Queirò ◽  
Marcel G. J. Tilanus ◽  
Roel A. Weger ◽  
Henk-Jan Schuurman
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Human T Cells ◽  
Variable Genes

Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase

Cell ◽  
1986 ◽  
Vol 44 (2) ◽  
pp. 251-259 ◽  
Author(s):  
George D. Yancopoulos ◽  
T.Keith Blackwell ◽  
Heikyung Suh ◽  
Leroy Hood ◽  
Frederick W. Alt
Keyword(s):  
T Cells ◽  
T Cell ◽  
B Cells ◽  
T Cell Receptor ◽  
Variable Region ◽  
Cell Receptor ◽  
Region Gene ◽  
Variable Region Gene

ANALYSIS OF VARIABLE REGION OF T-CELL RECEPTOR ?? CHAIN USAGE IN THE HUMAN ANTI-PORCINE XENORESPONSE1

1999 ◽  
Vol 68 (4) ◽  
pp. 586-589 ◽  
Author(s):  
Minchun Chen ◽  
Xiao-Chun Xu ◽  
William S. Wu ◽  
T. Mohanakumar
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Variable Region ◽  
Cell Receptor ◽  
Receptor Chain
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