scholarly journals The plasma insulin and growth hormone response to oral glucose: Diurnal and seasonal observations in the antarctic

Diabetologia ◽  
1975 ◽  
Vol 11 (2) ◽  
pp. 147-150 ◽  
Author(s):  
I. T. Campbell ◽  
R. J. Jarrett ◽  
P. Rutland ◽  
L. Stimmler
Keyword(s):  
Growth Hormone ◽  
Plasma Insulin ◽  
Growth Hormone Response ◽  
Oral Glucose ◽  
Hormone Response ◽  
The Antarctic

scholarly journals Growth hormone response to oral glucose load in untreated diabetic children.

1971 ◽  
Vol 46 (245) ◽  
pp. 117-119 ◽  
Author(s):  
C G Theodoridis ◽  
G W Chance ◽  
B T Rudd ◽  
G A Brown
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Response ◽  
Oral Glucose ◽  
Hormone Response ◽  
Oral Glucose Load ◽  
Glucose Load ◽  
Diabetic Children

The Effect of Hypoglycaemia on Oral Glucose Tolerance in Normal Subjects and Patients with Pituitary and Adrenal Disorders

1970 ◽  
Vol 39 (5) ◽  
pp. 663-674 ◽  
Author(s):  
N. W. Oakley ◽  
H. S. Jacobs ◽  
R. C. Turner ◽  
J. Williams ◽  
C. Dos ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Glucose Tolerance ◽  
Normal Subjects ◽  
Growth Hormone Response ◽  
Saline Control ◽  
Oral Glucose ◽  
Hormone Response ◽  
Oral Glucose Tolerance ◽  
Brittle Diabetes ◽  
Insulin Test

1. Hypoglycaemia induces glucose intolerance in normal subjects—the ‘Somogyi effect’–and may be responsible for some instances of ‘brittle diabetes’. This effect may be mediated through the growth hormone response to hypoglycaemia, but other possible hormonal mechanisms have not been excluded. 2. Paired 2-h oral glucose tolerance tests have been carried out 2 h after both (a) i.v. saline (control day) and (b) i.v. insulin (test day) in four normal subjects and twenty-seven patients with pituitary and adrenal under- and over-activity. Plasma glucose, insulin, Cortisol and growth hormone have been estimated at half-hourly intervals during the 4 h of each study. 3. A significant Somogyi effect is usually seen only when there is a growth hormone response to insulin-induced hypoglycaemia; hypopituitary subjects do not show the effect. 4. There is a correlation between the extent of the Somogyi effect and the growth hormone response to insulin, using a simple derived index to represent each function (P < 0·05). 5. Insulin secretion in normal subjects tends to be higher on the test than the control day, making inhibition of insulin release an unlikely primary mechanism. 6. The presence or absence of a Somogyi effect could not be related to insulin-induced changes in plasma Cortisol values. 7. Examination of individual cases supports the view that, while growth hormone may be mainly reponsible for the Somogyi effect, yet it is sometimes difficult to explain the effect without invoking other endocrine mechanisms.

Early changes in plasma glucagon and growth hormone response to oral glucose in experimental hyperthyroidism

Metabolism ◽  
1996 ◽  
Vol 45 (8) ◽  
pp. 1029-1033 ◽  
Author(s):  
Flavia Tosi ◽  
Paolo Moghetti ◽  
Roberto Castello ◽  
Carlo Negri ◽  
Enzo Bonora ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Response ◽  
Oral Glucose ◽  
Hormone Response ◽  
Plasma Glucagon ◽  
Experimental Hyperthyroidism

GROWTH-HORMONE RESPONSE TO ORAL GLUCOSE IN CHILDREN WITH SIMPLE OBESITY

The Lancet ◽  
1969 ◽  
Vol 293 (7605) ◽  
pp. 1068-1069 ◽  
Author(s):  
C.G. Theodoridis ◽  
G.W. Chance ◽  
G.A. Brown ◽  
P.H.W. Rayner
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Response ◽  
Oral Glucose ◽  
Hormone Response ◽  
Simple Obesity

THE EFFECT OF THE PROGESTOGEN ETHYNODIOL DIACETATE ON GLUCOSE, INSULIN, AND GROWTH HORMONE AFTER SIX MONTHS TREATMENT

1972 ◽  
Vol 70 (2) ◽  
pp. 373-384 ◽  
Author(s):  
W. N. Spellacy ◽  
W. C. Buhi ◽  
S. A. Birk
Keyword(s):  
Growth Hormone ◽  
Blood Glucose ◽  
Plasma Insulin ◽  
Tolerance Test ◽  
Metabolic Effects ◽  
Oral Glucose ◽  
Hormone Levels ◽  
Glucose Levels ◽  
Ethynodiol Diacetate ◽  
Tolerance Curve

ABSTRACT Seventy-one women were treated with a daily dose of 0.25 mg of the progestogen ethynodiol diacetate. They were all tested with a three-hour oral glucose tolerance test before beginning the steroid and then again during the sixth month of use. Measurements were made of blood glucose and plasma insulin and growth hormone levels. There was a significant elevation of the blood glucose levels after steroid treatment as well as a deterioration in the tolerance curve in 12.9% of the women. The plasma insulin values were also elevated after drug treatment whereas the fasting ambulatory growth hormone levels did not significantly change. There was a significant association between the changes in glucose and insulin levels and the subject's age, control weight, or weight gain during treatment. The importance of considering the metabolic effects of the progestogen component of oral contraceptives is stressed.

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