Isolation and structural analysis of two lipid A precursors from a KDO deficient mutant of Salmonella typhimurium differing in their hexadecanoic acid content

1985 ◽  
Vol 141 (4) ◽  
pp. 353-358 ◽  
Author(s):  
Thomas Hansen-Hagge ◽  
Volker Lehmann ◽  
Ulrich Seydel ◽  
Buko Lindner ◽  
Ulrich Z�hringer
Keyword(s):  
Structural Analysis ◽  
Salmonella Typhimurium ◽  
Acid Content ◽  
Lipid A ◽  
Deficient Mutant ◽  
Hexadecanoic Acid

scholarly journals Position of ester groups in the lipid A backbone of lipopolysaccharides obtained from Salmonella typhimurium.

1983 ◽  
Vol 258 (21) ◽  
pp. 12947-12951 ◽  
Author(s):  
N Qureshi ◽  
K Takayama ◽  
D Heller ◽  
C Fenselau
Keyword(s):  
Salmonella Typhimurium ◽  
Lipid A

Ein pseudoallel-spezifischer Suppressor bei Salmonella typhimurium

1956 ◽  
Vol 11 (6) ◽  
pp. 317-329 ◽  
Author(s):  
P. Starlinger ◽  
F. Kaudewitz
Keyword(s):  
Salmonella Typhimurium ◽  
Uv Irradiation ◽  
Genetic Material ◽  
Suppressor Gene ◽  
Growth Characteristics ◽  
Suppressor Mutation ◽  
Deficient Mutant ◽  
Colony Type ◽  
Gene Concept ◽  
Small Colony

In Salmonella typhimurium, UV-irradiation of the histidine-deficient mutant hi-31 induced a slowly growing reversion to histidine-independence. This formed colonies much smaller than wildtype. By means of transduction the newly created character “small colony” was proved to be heritable. As demonstrated by the following experiments this was due to an independant suppressor-mutation (S-31). After UV-irradiation of hi-31/S-31 a small fraction of cells forming large colonies, revealed growth-characteristics of wildtype. After transduction of small colony type cells by phages raised on wildtype the same large colonies were obtained. Expected to be of genotype hi-31+/S-31, they were used as donor for transduction of hi-31. Both, large colonies (hi-31+/S-31) and small colonies (hi-31/S-31) were isolated, which proved to be stable in further transfers.26 histidin-requiring mutants, belonging to 4 groups, each of them characterised by the same block in histidine synthesis, were transduced with phage raised on hi-31/S-31. None of them exhibited changes of growth characteristics, resulting from the incorporation of the suppressor-gene. Thus the suppressor S-31 turned out to be pseudoallel-specific.This result is considered as evidence that pseudoalleles of the histidine series in Salmonella typhimurium not only are units of recombination but also of function of genetic material. The differences between levels of functions exhibited by units which have been called pseudoalleles by various investigators are discussed in connection with the gene concept.

Structural analysis of the lipid A derived from the lipopolysaccharide of Brucella abortus

1994 ◽  
Vol 1 (3) ◽  
pp. 137-148 ◽  
Author(s):  
N. Qureshi ◽  
K. Takayama ◽  
U. Seydel ◽  
R. Wang ◽  
R.J. Cotter ◽  
...  
Keyword(s):  
Structural Analysis ◽  
Brucella Abortus ◽  
Lipid A
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