Distribution of plasma amino acids in humans during submaximal prolonged exercise

1974 ◽  
Vol 32 (2) ◽  
pp. 143-147 ◽  
Author(s):  
J. R. Poortmans ◽  
G. Siest ◽  
M. M. Galteau ◽  
O. Houot
Keyword(s):  
Amino Acids ◽  
Prolonged Exercise ◽  
Plasma Amino Acids

Effects of BCAA Supplementation on Plasma Amino Acids and on Subjective Fatigue and Muscle Soreness during Low-Intensity Prolonged Exercise

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S404
Author(s):  
Misaki Yoshida ◽  
Hiroko Tanaka ◽  
Takako Niijima ◽  
Masae Miyatani ◽  
Motohiko Miyachi ◽  
...  
Keyword(s):  
Amino Acids ◽  
Muscle Soreness ◽  
Prolonged Exercise ◽  
Plasma Amino Acids ◽  
Low Intensity ◽  
Subjective Fatigue

Improvement of Plasma Amino Acids During Fractionated Plasma Separation and Adsorption (Prometheus®)

2006 ◽  
Vol 44 (01) ◽  
Author(s):  
K Rifai ◽  
A Das ◽  
T Ernst ◽  
U Kretschmer ◽  
H Haller ◽  
...  
Keyword(s):  
Amino Acids ◽  
Plasma Amino Acids ◽  
Plasma Separation

LEVELS OF FREE PLASMA AMINO ACIDS UNDER ACUTE NORMOBARIC HYPOXIA IN VOLUNTEERS IN FASTED AND POSTPRANDIAL STATES

2020 ◽  
pp. 108-117
Author(s):  
A.A. Chernykh ◽  
N.N. Potolitsyna ◽  
E.A. Burykh ◽  
E.R. Boyko
Keyword(s):  
Amino Acids ◽  
Normobaric Hypoxia ◽  
Adaptation To Hypoxia ◽  
Plasma Amino Acids ◽  
Fed State ◽  
Metabolic Substrates ◽  
Overnight Fasting ◽  
Group 2 ◽  
Free Plasma ◽  
Group 1

The aim of the study was to assess the effect of acute normobaric hypoxia on free plasma amino acids (AA) in volunteers after overnight fasting and in the fed state. Materials and Methods. Group 1 (n=13, aged 22–32) participated in the study in the morning after overnight fasting. Group 2 (n=9, aged 22–32) took part in the study after a light fat-free breakfast. Acute normobaric hypoxia was achieved by breathing a hypoxic gas mixture (9 % O2 and 91 % N2) through a mask. According to the experimental protocol, blood sampling from the cubital vein was performed for analysis. Free plasma amino acids were analyzed using the Aracus amino acid analyzer. Results. Prior to the hypoxia onset, at the 5th and 20th minutes of hypoxia, no statistically significant differences in free AA levels were observed in the groups (p>0.05). At the 10th minute of hypoxia the levels of four AAs (serine, threonine, glutamine, and histidine) were significantly higher in Group 1 than in Group 2 (p<0.05). This was probably due to differences in functioning of several key “harmonizing” AA transporters (ASCT1 (SLC1A4), ASCT2 (SLC1A5) and LAT1 (SC7A5)), for which the AAs were metabolic substrates. It can be assumed, that such changes were caused by currently unclear mechanisms of fast regulation of AA transporter activity, associated with nutritional status. Conclusion. We believe that our findings may be important for providing better adaptation to hypoxia, and for more efficient correction of hypoxic negative effects. Keywords: acute normobaric hypoxia, free plasma amino acids, human. Цель исследования: изучить воздействие острой нормобарической гипоксии на метаболизм свободных аминокислот (АК) плазмы крови у добровольцев, участвовавших в исследовании натощак и после лёгкого завтрака. Материалы и методы. Первая группа добровольцев (22–32 года, n=13) участвовала в исследовании утром натощак, вторая группа (22–32 года, n=9) – через 2–3 ч после лёгкого безжирового завтрака. Гипоксия создавалась путём подачи через маску дыхательной смеси, содержащей 9 % О2 и 91 % N2. В соответствии с протоколом проводился периодический забор крови из локтевой вены для анализа. Оценка уровней свободных АК плазмы крови производилась с помощью аминокислотного анализатора Aracus. Результаты. До начала гипоксии, на 5-й и 20-й мин гипоксии уровни свободных АК в первой и второй группах значимо не различались (p>0,05). На 10-й мин гипоксии между первой и второй группами наблюдались статистически значимые различия уровней четырёх АК: глутамина, серина, треонина и гистидина (p<0,05). Это, вероятно, было обусловлено изменениями в работе «гармонизирующих» мембранных транспортёров (ASCT1 (SLC1A4), ASCT2 (SLC1A5) и LAT1 (SC7A5)), для которых эти АК являются обменными субстратами. Можно предположить, что данные изменения были опосредованы пока неясными механизмами быстрой регуляции активности этих транспортёров, зависящими от питания. Выводы. Мы полагаем, что полученные результаты могут иметь значение для обеспечения адаптации организма человека к острой гипоксии и эффективной коррекции последствий гипоксического воздействия. Ключевые слова: острая нормобарическая гипоксия, свободные аминокислоты плазмы крови, человек.

scholarly journals Plasma amino acids in patients with essential tremor

2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Shiroh Miura ◽  
Takashi Kamada ◽  
Ryuta Fujioka ◽  
Yoshihiro Yamanishi
Keyword(s):  
Amino Acids ◽  
Essential Tremor ◽  
Plasma Amino Acids

Effects of Prolonged Exercise on Brain Ammonia and Amino Acids

1998 ◽  
Vol 19 (05) ◽  
pp. 323-327 ◽  
Author(s):  
C. Guezennec ◽  
A. Abdelmalki ◽  
B. Seirurier ◽  
D. Merino ◽  
X. Bigard ◽  
...  
Keyword(s):  
Amino Acids ◽  
Prolonged Exercise

Diurnal rhythms in rat plasma amino acids

Life Sciences ◽  
1989 ◽  
Vol 45 (11) ◽  
pp. 979-986 ◽  
Author(s):  
T. Eriksson ◽  
K. Wiesel ◽  
L. Voog ◽  
M. Hagman
Keyword(s):  
Amino Acids ◽  
Rat Plasma ◽  
Diurnal Rhythms ◽  
Plasma Amino Acids

scholarly journals EFFECT OF AN ORAL ELEMENTAL DIET ON NITROGEN BALANCE AND PLASMA AMINO ACIDS

1974 ◽  
Vol 8 (4) ◽  
pp. 386-386 ◽  
Author(s):  
Joseph O Sherman ◽  
Carole-Ann Hamly ◽  
Avedis K Khachadurian ◽  
H L Nadler
Keyword(s):  
Amino Acids ◽  
Nitrogen Balance ◽  
Elemental Diet ◽  
Plasma Amino Acids

Quantitative Changes in Plasma Amino Acids Induced by Oral Contraceptives

1971 ◽  
Vol 41 (4) ◽  
pp. 301-307 ◽  
Author(s):  
I. L. Craft ◽  
T. J. Peters
Keyword(s):  
Amino Acids ◽  
Oral Contraceptives ◽  
Plasma Concentrations ◽  
Plasma Amino Acids ◽  
Total Plasma ◽  
Hormone Production ◽  
Contraceptive Pills ◽  
High Concentrations ◽  
Normal Women ◽  
Quantitative Changes

1. Plasma amino acids have been determined in healthy untreated women and in those receiving synthetic steroids to suppress ovulation. Both groups were studied early in the cycle when endogenous sex hormone production is low, and again later in the same cycle, when endogenous or exogenous hormones are at high concentrations respectively. 2. In normal women there is a significant decrease in plasma concentrations of serine, glutamate and ornithine, and of total amino acids in the second half of the cycle. 3. At this time those taking oral contraceptives have significant decreases in plasma concentrations of proline, glycine, alanine, valine, leucine and tyrosine, and of total plasma amino acids. In addition plasma glutamate, glycine, isoleucine and tyrosine concentrations are significantly lower than in normal women. 4. In the interval between completing one course of contraceptive pills and commencing the next, total plasma amino acid concentration reverts to normal, but a significant decrease in plasma glycine concentration persists. 5. It is suggested that these changes are due to the influence of endogenous and exogenous sex hormones respectively.

Analysis of plasma amino acids by HPLC with photodiode array and fluorescence detection

2005 ◽  
Vol 354 (1-2) ◽  
pp. 83-90 ◽  
Author(s):  
Elisabeth L. Schwarz ◽  
William L. Roberts ◽  
Marzia Pasquali
Keyword(s):  
Amino Acids ◽  
Fluorescence Detection ◽  
Plasma Amino Acids ◽  
Photodiode Array
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