scholarly journals Differential expression of rat pancreatic islet Beta-cell glucose transporter (GLUT 2), proinsulin and islet amyloid polypeptide genes after prolonged fasting, insulin-induced hypoglycaemia and dexamethasone treatment

Diabetologia ◽  
1992 ◽  
Vol 35 (12) ◽  
pp. 1125-1132 ◽  
Author(s):  
L. Koranyi ◽  
R. Bourey ◽  
J. Turk ◽  
M. Mueckler ◽  
M. A. Permutt
Keyword(s):  
Beta Cell ◽  
Glucose Transporter ◽  
Islet Amyloid Polypeptide ◽  
Fasting Insulin ◽  
Dexamethasone Treatment ◽  
Prolonged Fasting ◽  
Islet Amyloid ◽  
Pancreatic Islet Beta Cell ◽  
Cell Glucose ◽  
Rat Pancreatic Islet

Ruthenium complexes as inhibitors of human islet amyloid polypeptide aggregation, an effect that prevents beta cell apoptosis

RSC Advances ◽  
2015 ◽  
Vol 5 (23) ◽  
pp. 17405-17412 ◽  
Author(s):  
Lijuan Ma ◽  
Yuanting Fu ◽  
Lianling Yu ◽  
Xiaoling Li ◽  
Wenjie Zheng ◽  
...  
Keyword(s):  
Beta Cell ◽  
Cell Apoptosis ◽  
Cell Damage ◽  
Islet Amyloid Polypeptide ◽  
Ruthenium Complexes ◽  
Human Islet ◽  
Ros Generation ◽  
Beta Cell Apoptosis ◽  
Islet Amyloid ◽  
Application Potential

Herein we show that ruthenium complexes could inhibit fibrosis of hIAPP and protect the hIAPP-induced cell damage by suppressing ROS generation, indicating the application potential of the complexes in treatment of T2DM by targeting hIAPP.

scholarly journals Variability of the pancreatic islet beta cell/liver (GLUT 2) glucose transporter gene in NIDDM patients

Diabetologia ◽  
1994 ◽  
Vol 37 (4) ◽  
pp. 420-427 ◽  
Author(s):  
Y. Tanizawa ◽  
A. C. Riggs ◽  
J. M. Roseman ◽  
M. A. Permutt ◽  
K. C. Chiu ◽  
...  
Keyword(s):  
Beta Cell ◽  
Pancreatic Islet ◽  
Glucose Transporter ◽  
Transporter Gene ◽  
Islet Beta Cell ◽  
Pancreatic Islet Beta Cell ◽  
Niddm Patients

2126-P: Physiological Concentrations of IL-1 Beta Promote Islet Amyloid Deposition by Increasing Beta-Cell Secretion of Human Islet Amyloid Polypeptide

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2126-P
Author(s):  
ANDREW T. TEMPLIN ◽  
MAHNAZ MELLATI ◽  
DANIEL ZEMAN-MEIER ◽  
MEGHAN F. HOGAN ◽  
NATHALIE ESSER ◽  
...  
Keyword(s):  
Beta Cell ◽  
Islet Amyloid Polypeptide ◽  
Amyloid Deposition ◽  
Human Islet ◽  
Cell Secretion ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide ◽  
Beta Cell Secretion

scholarly journals Loss of prohormone convertase 2 promotes beta cell dysfunction in a rodent transplant model expressing human pro-islet amyloid polypeptide

Diabetologia ◽  
2016 ◽  
Vol 60 (3) ◽  
pp. 453-463 ◽  
Author(s):  
Jaques A. Courtade ◽  
Evan Y. Wang ◽  
Paul Yen ◽  
Derek L. Dai ◽  
Galina Soukhatcheva ◽  
...  
Keyword(s):  
Beta Cell ◽  
Islet Amyloid Polypeptide ◽  
Beta Cell Dysfunction ◽  
Prohormone Convertase ◽  
Islet Amyloid ◽  
Cell Dysfunction ◽  
Prohormone Convertase 2 ◽  
Transplant Model

scholarly journals Beta-cell selective KATP-channel activation protects beta-cells and human islets from human islet amyloid polypeptide induced toxicity

2010 ◽  
Vol 165 (2-3) ◽  
pp. 158-162 ◽  
Author(s):  
Robert A. Ritzel ◽  
Sajith Jayasinghe ◽  
John B. Hansen ◽  
Jeppe Sturis ◽  
Ralf Langen ◽  
...  
Keyword(s):  
Beta Cell ◽  
Beta Cells ◽  
Katp Channel ◽  
Islet Amyloid Polypeptide ◽  
Human Islets ◽  
Human Islet ◽  
Islet Amyloid ◽  
Channel Activation ◽  
Human Islet Amyloid Polypeptide

scholarly journals Regulation of beta-cell glucose transporter gene expression.

1990 ◽  
Vol 87 (11) ◽  
pp. 4088-4092 ◽  
Author(s):  
L. Chen ◽  
T. Alam ◽  
J. H. Johnson ◽  
S. Hughes ◽  
C. B. Newgard ◽  
...  
Keyword(s):  
Gene Expression ◽  
Beta Cell ◽  
Glucose Transporter ◽  
Transporter Gene ◽  
Cell Glucose
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