Diurnal variation of mood and the cortisol rhythm in depression and normal states of mind

1987 ◽  
Vol 237 (1) ◽  
pp. 36-45 ◽  
Author(s):  
D. Zerssen ◽  
P. Doerr ◽  
H. M. Emrich ◽  
R. Lund ◽  
K. M. Pirke
Keyword(s):  
Diurnal Variation ◽  
States Of Mind ◽  
Normal States ◽  
Diurnal Variation Of Mood

Diagnostic Significance of Vegetative Symptoms in Depression

1986 ◽  
Vol 148 (4) ◽  
pp. 442-446 ◽  
Author(s):  
Jonathan Davidson ◽  
Craig D. Turnbull
Keyword(s):  
Weight Loss ◽  
Diurnal Variation ◽  
Predictive Value ◽  
The Other ◽  
Melancholic Depression ◽  
Diagnostic Significance ◽  
Disturbed Sleep ◽  
Loss Of Libido ◽  
Diurnal Variation Of Mood ◽  
Diagnostic Importance

The diagnostic importance of vegetative symptoms for melancholia was examined through DSM-III, the Newcastle Scale, and Extracted Criteria for melancholia. Statistically significant differences were diagnostically unimpressive in the case of DSM-III and the Newcastle criteria. With the Extracted Criteria, initial insomnia, early waking, anorexia, weight loss, loss of libido, and worsened mood in the morning were all significantly more common in melancholia than in non-melancholic depression, while increased appetite was more common in non-melancholia. Only diurnal variation of mood (worse in the morning) showed predictive value for melancholia; whereas the other traditional vegetative symptoms (disturbed sleep, weight, and libido) did not. Increased appetite and diurnal variation of mood (worse in the evening) were predictive for non-melancholia.

Diurnal variation of mood and neuropsychological function in major depression with melancholia

1994 ◽  
Vol 32 (4) ◽  
pp. 257-269 ◽  
Author(s):  
A.P.R. Moffot ◽  
R.E. O'Carroll ◽  
J. Bennie ◽  
S. Carroll ◽  
H. Dick ◽  
...  
Keyword(s):  
Major Depression ◽  
Diurnal Variation ◽  
Neuropsychological Function ◽  
Diurnal Variation Of Mood

A longitudinal study of sleep deprivation responses in depression; The variability is highly related to diurnal mood variability

1995 ◽  
Vol 7 (2) ◽  
pp. 58-60 ◽  
Author(s):  
M.C.M. Gordijn ◽  
D.G.M. Beersma ◽  
A.L. Bouhuys ◽  
H.J. Korte ◽  
R.H. van den Hoofdakker
Keyword(s):  
Sleep Deprivation ◽  
Diurnal Variation ◽  
Positive Response ◽  
Diurnal Variations ◽  
Cross Sectional ◽  
Antidepressive Effect ◽  
Mood Variability ◽  
Mood Changes ◽  
Diurnal Variation Of Mood ◽  
The Relationship

Unequivocal results demonstrating a causal relationship between a disturbance in circadian rhythms and depression have not yet been reported (reviews). However, acute mood changes, such as the antidepressive effect of sleep deprivation, diurnal variations of mood and their interrelationship, are commonly put forward as evidence of the importance of circadian dysregulations in affective disorders. The purpose of the present study is to obtain more insight in the mechanisms underlying these mood changes. The results will be discussed in the context of a recently postulated non-chronobiological explanation.Earlier studies have suggested that the relationship between diurnal variation of mood and the response to total sleep deprivation (TSD) is clear and unambiguous: improvement of mood during the day prior to TSD (a positive diurnal variation) is followed by a positive response (mood improvement) to TSD, while no improvement or deterioration of mood during the day prior to TSD (a negative diurnal variation) may result in no, or even a negative, TSD response (for references see Van den Hoofdakker). However, these conclusions were based on the results from cross-sectional studies, comparing single TSD effects across individuals. Comparison of sleep deprivation effects within individuals, however, revealed that the course of mood during the day prior to TSD is irrelevant for the TSD response. Accordingly, a favourable response to TSD appeared to be related to the patient's propensity to show diurnal mood variations per se, irrespective of their direction.

Response of Depressive Symptoms to Nortriptyline, Phenelzine and Placebo

1987 ◽  
Vol 151 (1) ◽  
pp. 102-106 ◽  
Author(s):  
Anastasios Georgotas ◽  
Robert E. Mccue ◽  
Eitan Friedman ◽  
Thomas B. Cooper
Keyword(s):  
Depressive Symptoms ◽  
Suicidal Ideation ◽  
Major Depression ◽  
Diurnal Variation ◽  
Symptoms Of Depression ◽  
Diurnal Variation Of Mood ◽  
Better Than

The effects of nortriptyline, phenelzine, and placebo on 13 symptoms of depression were compared in 75 patients, aged 55 or over, who were suffering from major depression. Nortriptyline and phenelzine were more effective than placebo in treating depression mood, guilt feelings, suicidal ideation, agitation, anxiety, loss of energy, and a.m. diurnal variation of mood. Nortriptyline was better than phenelzine or placebo in improving middle/late insomnia. Most of the symptoms did not show significant improvement until the fourth week of treatment.

DIURNAL VARIATION OF MOOD AND SLEEP DEPRIVATION IN DEPRESSED PATIENTS

1992 ◽  
Vol 3 (Supplement) ◽  
pp. 50
Author(s):  
E REININK ◽  
A L BOUHUYS ◽  
R H VAN DEN HOOFDAKKER
Keyword(s):  
Sleep Deprivation ◽  
Diurnal Variation ◽  
Depressed Patients ◽  
Diurnal Variation Of Mood

Psychiatric Drugging of Children and Youth as a Form of Child Abuse: Not a Radical Proposition

2017 ◽  
Vol 19 (1) ◽  
pp. 65-76 ◽  
Author(s):  
Bonnie Burstow
Keyword(s):  
Child Abuse ◽  
Drug Research ◽  
Children And Youth ◽  
States Of Mind ◽  
Adult Behavior ◽  
Rights Of The Child ◽  
United Nations Convention ◽  
Normal States ◽  
Made In

Although affirming that the psychiatric drugging of children constitutes both adultism (oppression based on treating adult behavior as normative) and sanism (oppression based on prioritizing what are seen as “normal” states of mind), and noting the role of pharmaceutical profit in what is happening, this article argues that in the strictest sense of the term the psychiatric drugging of children is a form of child abuse. It attempts to demonstrate not only that is this a form of child abuse but also that such a claim itself, as radical as it seems, follows from a combination of drug research and conventional understandings of abuse. The article further examines inaccurate claims about psychiatric drugs and the damage which they actually do. It proceeds to demonstrate that what is happening with respect to children constitutes child abuse as conventionally defined. Particularly focal is the United Nations Convention on the Rights of the Child. Action recommendations made in accordance with the findings include consciousness-raising and the launching of law suits at all levels.

Effects of partial sleep deprivation on the diurnal variation of mood and motor activity in major depression

1991 ◽  
Vol 30 (8) ◽  
pp. 817-829 ◽  
Author(s):  
Martin P. Szuba ◽  
Lewis R. Baxter ◽  
Lynn A. Fairbanks ◽  
Barry H. Guze ◽  
Jeffrey M. Schwartz
Keyword(s):  
Major Depression ◽  
Motor Activity ◽  
Sleep Deprivation ◽  
Diurnal Variation ◽  
Partial Sleep Deprivation ◽  
Diurnal Variation Of Mood

Reversed diurnal variation in depression: associations with a differential antidepressant response, tryptophan:large neutral amino acid ratio and serotonin transporter polymorphisms

2005 ◽  
Vol 35 (4) ◽  
pp. 511-517 ◽  
Author(s):  
PETER R. JOYCE ◽  
RICHARD J. PORTER ◽  
ROGER T. MULDER ◽  
SUZANNE E. LUTY ◽  
JANICE M. McKENZIE ◽  
...  
Keyword(s):  
Amino Acid ◽  
Diurnal Variation ◽  
Serotonin Transporter ◽  
Neutral Amino Acid ◽  
Antidepressant Response ◽  
Bipolar Ii Disorder ◽  
Acid Ratio ◽  
Bipolar Ii ◽  
Diurnal Variation Of Mood ◽  
Serotonergic Antidepressant

Background. Although diurnal variation of mood is a widely recognized symptom of depression, the clinical, neurobiological and psychopharmacological significance of this symptom has not previously been reported.Method. A total of 195 depressed out-patients underwent a detailed clinical and neurobiological assessment, and were then randomized to treatment with either fluoxetine or nortriptyline.Results. Of the 195 depressed patients, 62 had a pattern of reversed diurnal variation (i.e. worse in the evening). Those with reversed diurnal variation had a poorer response to a serotonergic antidepressant, were less likely to have bipolar II disorder, had a higher tryptophan:large neutral amino acid ratio and had different allele frequencies of the polymorphisms in the promoter region of the serotonin transporter.Conclusions. These findings raise the possibility of serotonergic influence on diurnal variation, and that the symptom of reversed diurnal variation is of relevance to antidepressant prescribing.

Sign in / Sign up

Export Citation Format

Share Document