Central composite experimental design in the optimization of lignin peroxidase production in shake cultures by free and immobilized Phanerochaete chrysosporium

1990 ◽  
Vol 6 (1-2) ◽  
pp. 43-48 ◽  
Author(s):  
S. Linko ◽  
L. -C. Zhong
Keyword(s):  
Experimental Design ◽  
Phanerochaete Chrysosporium ◽  
Lignin Peroxidase ◽  
Central Composite Experimental Design ◽  
Central Composite ◽  
Lignin Peroxidase Production

Supramolecular solvent-based microextraction method for cobalt traces in food samples with optimization Plackett–Burman and central composite experimental design

RSC Advances ◽  
2015 ◽  
Vol 5 (115) ◽  
pp. 94879-94886 ◽  
Author(s):  
Funda Aydin ◽  
Erkan Yilmaz ◽  
Mustafa Soylak
Keyword(s):  
Experimental Design ◽  
Atomic Absorption Spectrometry ◽  
Flame Atomic Absorption Spectrometry ◽  
Absorption Spectrometry ◽  
Optimization Method ◽  
Food Samples ◽  
Flame Atomic Absorption ◽  
Supramolecular Solvent ◽  
Central Composite Experimental Design ◽  
Central Composite

A new microextraction method based on formation of supramolecular solvent (Ss) was developed by using of chemometric optimization method for cobalt determination with microsampling flame atomic absorption spectrometry (MS-FAAS).

Evaluation of methyl chavicol concentration by different evaporation processes using central composite experimental design

2012 ◽  
Vol 98 ◽  
pp. 464-471 ◽  
Author(s):  
Patricia Fazzio Martins ◽  
Claudio Carmona ◽  
Edgar Leonardo Martinez ◽  
Paula Sbaite ◽  
Rubens Maciel Filho ◽  
...  
Keyword(s):  
Experimental Design ◽  
Methyl Chavicol ◽  
Central Composite Experimental Design ◽  
Central Composite

Central Composite experimental design applied to removal of lead and nickel from sand

2009 ◽  
Vol 172 (2-3) ◽  
pp. 1087-1092 ◽  
Author(s):  
V.V. Guaracho ◽  
N.M.S. Kaminari ◽  
M.J.J.S. Ponte ◽  
H.A. Ponte
Keyword(s):  
Experimental Design ◽  
Central Composite Experimental Design ◽  
Central Composite

scholarly journals Optimization by Central Composite Experimental Design of the Synthesis of Physically Crosslinked Chitosan Spheres

Biomimetics ◽  
2020 ◽  
Vol 5 (4) ◽  
pp. 63
Author(s):  
Sara Isabel Zamora Lagos ◽  
Jefferson Murillo Salas ◽  
Mayra Eliana Valencia Zapata ◽  
José Herminsul Mina Hernández ◽  
Carlos David Grande Tovar
Keyword(s):  
Tissue Engineering ◽  
Experimental Design ◽  
Biological Properties ◽  
Sphere Diameter ◽  
Naoh Solution ◽  
Central Composite Experimental Design ◽  
Physically Crosslinked ◽  
Needle Diameter ◽  
Central Composite ◽  
Crosslinking Agents

Chitosan (CS) has special properties such as biocompatibility, biodegradability, antibacterial, and biological activity which make this material is currently studied in various applications, including tissue engineering. There are different methods to modify the morphology of CS. Most use chemical crosslinking agents, however, those methods have disadvantages such as low polymer degradability and unwanted side effects. The objective of this research was to obtain CS spheres through the physical crosslinking of commercial CS without using crosslinking agents through a simple coacervation method. A central composite experimental design was used to optimize the synthesis of the CS spheres and by the response surface methodology it was possible to obtain CS spheres with the smallest diameter and the most regular morphology. With the optimal formulation (CS solution 1.8% (w/v), acetic acid (AAC) solution 1% (w/v), sodium hydroxide (NaOH) solution 13% (w/v), relative humidity of (10%) and needle diameter of 0.6 mm), a final sphere diameter of 1 mm was obtained. Spheres were characterized by physical, chemical, thermal, and biological properties in simulated body fluid (SBF). The results obtained allowed us to understand the effect of the studied variables on the spheres’ diameter. An optimized condition facilitated the change in the morphology of the CS while maintaining its desirable properties for use in tissue engineering.

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