A single linkage group comprising 11 polymorphic DNA markers on rat Chromosome 3

1994 ◽  
Vol 5 (9) ◽  
pp. 538-541 ◽  
Author(s):  
H. Zha ◽  
E. F. Remmers ◽  
Y. Du ◽  
E. A. Goldmuntz ◽  
P. Mathern ◽  
...  
Genomics ◽  
2006 ◽  
Vol 87 (1) ◽  
pp. 1-29 ◽  
Author(s):  
June E. Swinburne ◽  
Mike Boursnell ◽  
Gemma Hill ◽  
Louise Pettitt ◽  
Twink Allen ◽  
...  

2004 ◽  
Vol 2004 (1) ◽  
pp. 52-60 ◽  
Author(s):  
My A. Kassem ◽  
K. Meksem ◽  
M. J. Iqbal ◽  
V. N. Njiti ◽  
W. J. Banz ◽  
...  

Soybean seeds contain large amounts of isoflavones or phytoestrogens such as genistein, daidzein, and glycitein that display biological effects when ingested by humans and animals. In seeds, the total amount, and amount of each type, of isoflavone varies by 5 fold between cultivars and locations. Isoflavone content and quality are one key to the biological effects of soy foods, dietary supplements, and nutraceuticals. Previously we had identified 6 loci (QTL) controlling isoflavone content using 150 DNA markers. This study aimed to identify and delimit loci underlying heritable variation in isoflavone content with additional DNA markers. We used a recombinant inbred line (RIL) population (n=100) derived from the cross of “Essex” by “Forrest,” two cultivars that contrast for isoflavone content. Seed isoflavone content of each RIL was determined by HPLC and compared against 240 polymorphic microsatellite markers by one-way analysis of variance. Two QTL that underlie seed isoflavone content were newly discovered. The additional markers confirmed and refined the positions of the six QTL already reported. The first new region anchored by the marker BARC-Satt063 was significantly associated with genistein (P=0.009,R2=29.5%) and daidzein (P=0.007,R2=17.0%). The region is located on linkage group B2 and derived the beneficial allele from Essex. The second new region defined by the marker BARC-Satt129 was significantly associated with total glycitein (P=0.0005,R2=32.0%). The region is located on linkage group D1a+Q and also derived the beneficial allele from Essex. Jointly the eight loci can explain the heritable variation in isoflavone content. The loci may be used to stabilize seed isoflavone content by selection and to isolate the underlying genes.


1985 ◽  
Vol 35 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Masahiko MAEKAWA ◽  
Fumiji KITA

1998 ◽  
Vol 123 (6) ◽  
pp. 1016-1022 ◽  
Author(s):  
Dror Sharon ◽  
Jossi Hillel ◽  
Samir Mhameed ◽  
Perry B. Cregan ◽  
Emanuel Lahav ◽  
...  

The detection of association between DNA markers and traits of interest in an outbred population is complicated and requires highly polymorphic markers. A genetic linkage map of avocado (Persea americana Mill.) recently generated consists of simple sequence repeat (SSR) markers as well as DNA fingerprint (DFP) and randomly amplified polymorphic DNA (RAPD) markers. These markers were used to detect putative quantitative trait loci (QTLs) of eight avocado fruit traits. Two statistical methods were used: one-way analysis of variance and interval mapping. Six traits were found to be associated with at least one of the 90 DNA markers. Based on the two statistical approaches, a putative QTL associated with the presence of fibers in the flesh, was found to be located on linkage group 3. This putative QTL was found to be associated with the SSR marker AVA04 having a high significant value (P = 4.4 × 10-8). The haplotype analysis of linkage group 3 showed a putative dominant interaction between the alleles of this locus.


1982 ◽  
Vol 2 (11) ◽  
pp. 1399-1409 ◽  
Author(s):  
S Klapholz ◽  
R E Esposito

We present several lines of evidence that chromosomes XIV and XVII of Saccharomyces cerevisiae are not independent chromosomes, but rather constitute a single linkage group. Studies which made use of a new mapping method based on the haploidization-without-recombination meiotic phenotype of the spoll mutant initially indicated that markers on chromosomes XIV and XVII were linked. Tetrad analysis was used to establish gene-gene distances, and a new chromosome XIV map incorporating markers originally assigned to chromosome XVII was derived. During the course of trisomic segregation studies, we discovered that a 2n + 2 homothallic diploid, originally believed to be tetrasomic for chromosome XVII (now XIV), carries two normal chromosome XIV homologs and two aberrant homologs which appear to be deficient for a large portion of the right arm of XIV. The previous evidence that established chromosome XVII as an independent linkage group is discussed in the light of these findings.


Genomics ◽  
1992 ◽  
Vol 14 (3) ◽  
pp. 618-623 ◽  
Author(s):  
Elaine F. Remmers ◽  
Ellen A. Goldmuntz ◽  
Joseph M. Cash ◽  
Leslie J. Crofford ◽  
Barbara Misiewicz-Poltorak ◽  
...  

1994 ◽  
Vol 36 (7) ◽  
pp. 434-442 ◽  
Author(s):  
Robin Sherrington ◽  
David Curtis ◽  
Jon Brynjolfsson ◽  
Eamonn Moloney ◽  
Larry Rifkin ◽  
...  

2016 ◽  
Vol 25 (3) ◽  
Author(s):  
Pirjo Tanhuanpää ◽  
Mika Isolahti ◽  
Nissinen Oiva ◽  
Outi Manninen

The objective of the study was to find DNA markers associated with resistance to Typhula ishikariensis in timothy (Phleum pratense L.) using bulked-segregant analysis. A progeny of 161 F1 individuals was created by crossing the Finnish resistant cultivar Tammisto II with the Japanese susceptible cultivar Nosappu. Six to ten clones of each F1 individual were tested for resistance in the greenhouse, and a survival index, which was based both on survival and the ability of plants to recover, was calculated for each F1 to describe resistance. Resistant and susceptible bulks of eight individuals in each were screened with a total of 292 primer combinations. Six DNA markers were found to be associated with resistance, together explaining 15% of phenotypic variation in Typhula resistance. Four of the markers formed one linkage group, which contained a QTL explaining 7% of the variation in Typhula resistance.


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