Genetic map of rat Chromosome 5 including the fatty (fa) locus

1995 ◽  
Vol 6 (1) ◽  
pp. 25-30 ◽  
Author(s):  
G. E. Truett ◽  
H. J. Jacob ◽  
J. Miller ◽  
G. Drouin ◽  
N. Bahary ◽  
...  
Keyword(s):  
Genetics ◽  
1997 ◽  
Vol 146 (3) ◽  
pp. 1049-1060 ◽  
Author(s):  
David P King ◽  
Martha Hotz Vitaterna ◽  
Anne-Marie Chang ◽  
William F Dove ◽  
Lawrence H Pinto ◽  
...  

Clock is a semidominant mutation identified from an N-ethyl-N-nitrosourea mutagenesis screen in mice. Mice carrying the Clock mutation exhibit abnormalities of circadian behavior, including lengthening of endogenous period and loss of rhythmicity. To identify the gene affected by this mutation, we have generated a high-resolution genetic map (>1800 meioses) of the Clock locus. We report that Clock is 0.7 cM distal of Kit on mouse chromosome 5. Mapping shows that Clock lies within the W19H deletion. Complementation analysis of different Clock and W19H compound genotypes indicates that the Clock mutation behaves as an antimorph. This antimorphic behavior of Clock strongly argues that Clock defines a gene centrally involved in the mammalian circadian system.


Genomics ◽  
1994 ◽  
Vol 23 (3) ◽  
pp. 685-690 ◽  
Author(s):  
Marie-Claire Beckers ◽  
Isabelle Bar ◽  
Thanh Huynh-Thu ◽  
Christiane Dernoncourt ◽  
Ana Lúcia Brunialti ◽  
...  

Genome ◽  
1989 ◽  
Vol 32 (5) ◽  
pp. 925-929 ◽  
Author(s):  
Melody Clark ◽  
Angela Karp ◽  
Simon Archer

Physical mapping of the B-hordein genes in barley (Hordeum vulgare cv. Betzes) was achieved by in situ hybridization of a biotin-labelled B-hordein cRNA probe to chromosome spreads. Lines trisomic for chromosome 5 showed up to 3 signals on interphase nuclei, while no more than 2 signals were observed in normal diploids. An enzyme pretreatment, which produced broken cells, increased the frequency of signal detection. A clear signal was observed on 23% of interphase nuclei and 0.025% of metaphase spreads. The B-hordein genes mapped to 46% of the distance from the centromere on the short arm of chromosome 5. These results are discussed in relation to the barley genetic map and to previous reports of in situ hybridization of low-copy and unique-copy genes in plants.Key words: in situ hybridization, Hordeum vulgare, B-hordein genes, genetic map.


1993 ◽  
Vol 4 (11) ◽  
pp. 670-675 ◽  
Author(s):  
Ellen A. Goldmuntz ◽  
Elaine F. Remmers ◽  
Hongbin Zha ◽  
Peter Mathern ◽  
Ying Du ◽  
...  

Nature ◽  
2007 ◽  
Author(s):  
Alison Abbott
Keyword(s):  

2010 ◽  
Author(s):  
Zhi-Qiang Du ◽  
Suneel K. Onteru ◽  
Danielle Gorbach ◽  
Max F. Rothschild

Sign in / Sign up

Export Citation Format

Share Document