Effects of exercise on skeletal muscle and serum enzyme activities in pigs

1989 ◽  
Vol 13 (5) ◽  
pp. 341-347 ◽  
Author(s):  
F. Doiz� ◽  
R. Laporte ◽  
L. Deroth
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activities ◽  
Serum Enzyme

Serum carnosinase activities in patients with alcoholic chronic skeletal muscle myopathy

1988 ◽  
Vol 75 (2) ◽  
pp. 185-190 ◽  
Author(s):  
P. Duane ◽  
T. J. Peters
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activity ◽  
Enzyme Activities ◽  
Muscle Fibres ◽  
Significant Activity ◽  
Type Ii ◽  
Normal Muscle ◽  
Serum Enzyme ◽  
Chronic Alcoholic ◽  
Muscle Biopsies

1. Serum carnosinase activity was assayed in a group of alcoholic patients with and without histologically proven atrophy of type II skeletal muscle fibres, and in control subjects. No significant activity was detected in muscle biopsy samples or washed erythrocytes. 2. Serum carnosinase activity was significantly lower in chronic alcoholic patients compared with a group of age-matched controls. Alcoholics with abnormal muscle biopsies had significantly lower enzyme activities than either those patients with normal muscle biopsies or the controls. Serum enzyme activities in patients with normal muscle biopsies were not significantly different from controls. 3. Serum carnosinase activity was inversely correlated with the degree of muscle atrophy as measured by the type II fibre atrophy factor. There was a positive correlation between the enzyme activity and skeletal muscle mass as reflected by the creatinine-height index. Furthermore, the enzyme activity significantly increased, with resolution or improvement in the myopathy, in patients who abstained from alcohol. 4. Kinetic studies showed that the reduced carnosinase activity was due mainly to a decrease in the apparent Vmax. The apparent Km was significantly higher in the myopathic compared with non-myopathic alcoholics. Mixing serum from controls and patients with myopathy gave the expected values, indicating the absence of a serum enzyme inhibitory factor. Acute alcohol loading had no effect on the serum carnosinase activity. 5. The decrease in serum carnosinase activity in alcoholics was not related to the severity of their liver disease. Assays of serum carnosinase in chronic alcoholics can thus be used as a marker of their associated myopathy.

Effects of Chronic Ethanol Abuse on Structure and Enzyme Activities of Skeletal Muscle in Man

1975 ◽  
Vol 35 (6) ◽  
pp. 601-607 ◽  
Author(s):  
K. -H. Kiessling ◽  
L. Pilström ◽  
A. -C. Bylund ◽  
K. Piehl ◽  
B. Saltin
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activities ◽  
Chronic Ethanol ◽  
Ethanol Abuse

Enzyme studies of skeletal muscle in mice with hereditary muscular dystrophy

1963 ◽  
Vol 205 (5) ◽  
pp. 897-901 ◽  
Author(s):  
Marilyn W. McCaman
Keyword(s):  
Skeletal Muscle ◽  
Muscular Dystrophy ◽  
Glutathione Reductase ◽  
Enzyme Activities ◽  
Lactic Dehydrogenase ◽  
Normal Muscle ◽  
Dystrophic Muscle ◽  
Nerve Section ◽  
Mouse Muscle ◽  
Dystrophic Mouse

The activities of 20 enzymes in normal, heterozygous, and dystrophic mouse muscle were studied by means of quantitative microchemical methods. Enzyme activities in normal and heterozygous muscle were essentially the same. In dystrophic muscle glucose-6-P dehydrogenase, 6-P-gluconic dehydrogenase, glutathione reductase, peptidase, ß-glucuronidase, and glucokinase activities were significantly higher than in normal muscle, while α-glycero-P dehydrogenase and lactic dehydrogenase activities were significantly lower. The pattern of enzyme activities found in normal gastrocnemius denervated by nerve section was strikingly similar to that in dystrophic muscle.

scholarly journals Anaerobic and Aerobic Enzyme Activities in Human Skeletal Muscle from Children and Adults

2005 ◽  
Vol 57 (3) ◽  
pp. 331-335 ◽  
Author(s):  
Jan J Kaczor ◽  
Wieslaw Ziolkowski ◽  
Jerzy Popinigis ◽  
Mark A Tarnopolsky
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activities ◽  
Human Skeletal Muscle

scholarly journals Serum enzyme activities after cardioversion

Heart ◽  
1970 ◽  
Vol 32 (5) ◽  
pp. 600-602 ◽  
Author(s):  
T. Mandecki ◽  
L. Giec ◽  
W. Kargul
Keyword(s):  
Enzyme Activities ◽  
Serum Enzyme
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