The yield of synaptosomes from the cerebral cortex of guinea pigs estimated by a polystyrene bead ?tagging? procedure

1966 ◽  
Vol 72 (1) ◽  
pp. 126-138 ◽  
Author(s):  
F. Clementi ◽  
V. P. Whittaker ◽  
M. N. Sheridan
Keyword(s):  
Cerebral Cortex ◽  
Guinea Pigs ◽  
Polystyrene Bead

Free amino acid concentrations in cerebral cortex of guinea pigs with epileptogenic lesions

1962 ◽  
Vol 5 (6) ◽  
pp. 525-532 ◽  
Author(s):  
Yo Aelony ◽  
John Logothetis ◽  
Bruce Bart ◽  
Frank Morrell ◽  
Magdaline Bovis
Keyword(s):  
Cerebral Cortex ◽  
Amino Acid ◽  
Free Amino Acid ◽  
Guinea Pigs ◽  
Free Amino ◽  
Amino Acid Concentrations

THE UPTAKE AND DISTRIBUTION OF 14C-CLOMIPHENE CITRATE IN DIFFERENT ORGANS OF NEWBORN FEMALE GUINEA PIGS

1971 ◽  
Vol 68 (3) ◽  
pp. 605-613 ◽  
Author(s):  
K.-D. Schulz ◽  
F. Hölzel ◽  
G. Bettendorf
Keyword(s):  
Cerebral Cortex ◽  
Adrenal Gland ◽  
Guinea Pigs ◽  
Microsomal Fraction ◽  
Clomiphene Citrate ◽  
Time Intervals ◽  
Hypothalamic Region ◽  
Single Subcutaneous Injection ◽  
High Affinity ◽  
Labelled Compound

ABSTRACT Newborn female guinea pigs received a single subcutaneous injection of 150 μg 14C-clomiphene/l00 g body weight. At different time intervals after clomiphene administration the radioactivity was measured in the cerebral cortex, hypothalamic region, pituitary, ovary, liver, adrenal gland and uterus. As early as 1 hour after injection 14C-activity was detectable in all the organs examined. Corresponding to the well-known anti-oestrogenic and oestrogen-like activities of clomiphene, the oestrogenresponsive tissues of the hypothalamic region, pituitary and uterus indicated a high affinity for this compound. Compared with the cerebral cortex, these organs showed a 2- to 7-fold incorporation of 14C-radioactivity 3 hours after the injection. In the uterus a rather constant 14Clevel was maintained during a period of 25 hours. A high uptake and retention of the labelled compound were also detectable in the liver and the adrenal gland. The ovary has the capacity to accumulate a large amount of the 14C-labelled substance. But this ability is only demonstrable during the first 6 hours after clomiphene administration; after this the 14C-activity decreases rapidly, like the 14C-level in the blood plasma. The relevance of this result for the direct effect of clomiphene on ovarian stereoidogenesis is discussed. Furthermore the distribution of l4C-clomiphene was studied in the nuclear, mitochondrial and microsomal fraction and in the particle free supernatant of the above mentioned organs.

scholarly journals Effect of hypoxia on heat-shock proteins (HSPs) in the cerebral cortex of the guinea-pigs newborns

1999 ◽  
Vol 45 (6) ◽  
pp. 907-907
Author(s):  
Giuseppe Buonocore ◽  
Sabrina Liberatori ◽  
Luca Bini ◽  
Vitaliano Pallini ◽  
Om P Mishra ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Guinea Pigs ◽  
Shock Proteins

scholarly journals HYPOXIA-INDUCED MODIFICATION OF GUANOSINE IN THE CEREBRAL CORTEX OF FETAL GUINEA PIGS. † 370

1996 ◽  
Vol 39 ◽  
pp. 64-64
Author(s):  
Om P Mishra ◽  
Alan B Zubrow ◽  
Peter J Marro ◽  
Joanna Kubin ◽  
Maria Delivoria-Papadopoulos
Keyword(s):  
Cerebral Cortex ◽  
Guinea Pigs

Effect of haloperidol and pimozide on acetylcholine output from the cerebral cortex in rats and guinea pigs

1980 ◽  
Vol 65 (2-3) ◽  
pp. 279-284 ◽  
Author(s):  
Fiorella Casamenti ◽  
Clementina Bianchi ◽  
Lorenzo Beani ◽  
Giancarlo Pepeu
Keyword(s):  
Cerebral Cortex ◽  
Guinea Pigs

scholarly journals S. Mikhailov. On the question of the development of motor centers of the cerebral cortex of newborns. Doctor. Bulletin No. 6-7, 1910

2021 ◽  
Vol XVIII (1) ◽  
pp. 200-201
Author(s):  
Ivan Dmitrievich Baklushinskiy
Keyword(s):  
Cerebral Cortex ◽  
Guinea Pigs

Based on his experiments on puppies and guinea pigs, the author draws conclusions

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