Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus

1988 ◽  
Vol 61 (3) ◽  
pp. 165-179 ◽  
Author(s):  
Hans-Joachim Merker ◽  
Wolfgang Heger ◽  
Klaus Sames ◽  
Helga St�rje ◽  
Diether Neubert
Keyword(s):  
Callithrix Jacchus ◽  
Embryotoxic Effects ◽  
Human Primate

Embryotoxic effects of thalidomide derivatives in the non-human primate Callithrix jacchus

1988 ◽  
Vol 61 (3) ◽  
pp. 180-191 ◽  
Author(s):  
Diether Neubert ◽  
Wolfgang Heger ◽  
Hans-Joachim Merker ◽  
Klaus Sames ◽  
Reinhard Meister
Keyword(s):  
Callithrix Jacchus ◽  
Embryotoxic Effects ◽  
Human Primate

scholarly journals Expression pattern of WOLFRAMIN, the Wolfram syndrome 1 (WFS1) gene product, in the Common Marmoset (Callithrix jacchus), a non-human primate, cochlea

2016 ◽  
Vol 130 (S3) ◽  
pp. S236-S236
Author(s):  
Noriomi Suzuki ◽  
Masato Fujioka ◽  
Makoto Hosoya ◽  
Naoki Oishi ◽  
Seiji Shiozawa ◽  
...  
Keyword(s):  
Gene Product ◽  
Expression Pattern ◽  
Common Marmoset ◽  
Wolfram Syndrome ◽  
Callithrix Jacchus ◽  
The Common ◽  
Wfs1 Gene ◽  
Human Primate

scholarly journals A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset (Callithrix jacchus)

10.3791/56574 ◽  
2018 ◽  
Author(s):  
Sho Kurihara ◽  
Masato Fujioka ◽  
Tomohiko Yoshida ◽  
Makoto Koizumi ◽  
Kaoru Ogawa ◽  
...  
Keyword(s):  
Inner Ear ◽  
Surgical Procedure ◽  
Common Marmoset ◽  
Callithrix Jacchus ◽  
Human Primate

scholarly journals Breathing Behaviors in Common Marmoset (Callithrix jacchus)

2020 ◽  
Author(s):  
Mitchell Bishop ◽  
Ariana Z. Turk ◽  
Shahriar SheikhBahaei
Keyword(s):  
Tidal Volume ◽  
Hypoxic Condition ◽  
Common Marmoset ◽  
Callithrix Jacchus ◽  
The Body ◽  
Whole Body ◽  
Common Marmosets ◽  
Freely Behaving ◽  
Whole Body Plethysmography ◽  
Human Primate

AbstractThe respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of frequency and dept (tidal volume) of breathing. The use of common marmoset (Callithrix jacchus), a New World non-human primate (NHP) model, in neuroscience is increasing, however, the data on their breathing is limited and their respiratory behaviors have yet to be characterized. Using Whole-body Plethysmography in room air as well as in hypoxic (low O2) and hypercapnic (high CO2) conditions, we sought to define breathing behaviors in an awake, freely behaving marmosets. Additionally, we instituted and optimized an analysis toolkit for unsupervised analysis of the respiratory activities in common marmoset. Our findings indicate that marmoset’s exposure to hypoxia decreased metabolic rate and increased sigh rate. However, the hypoxic condition did not augment the ventilatory response as reported in other animals. Hypercapnia, on the other hand, increased both the frequency and tidal volume as expected. In this study, we shed light on the breathing behaviors of common marmosets in a variety of O2 and CO2 conditions to further understand the breathing behaviors in NHPs.

scholarly journals GB virus B infection of the common marmoset (Callithrix jacchus) and associated liver pathology

2004 ◽  
Vol 85 (9) ◽  
pp. 2525-2533 ◽  
Author(s):  
James R. Jacob ◽  
Kuei-Chin Lin ◽  
Bud C. Tennant ◽  
Keith G. Mansfield
Keyword(s):  
Acute Hepatitis ◽  
New World ◽  
Antiviral Drug ◽  
Common Marmoset ◽  
Callithrix Jacchus ◽  
Primate Species ◽  
New World Primates ◽  
Common Marmosets ◽  
The Common ◽  
Human Primate

GB virus B (GBV-B) is a flavivirus that is related closely to hepatitis C virus (HCV) and induces an acute hepatitis when inoculated into several species of New World primates. Common marmosets (Callithrix jacchus) are a widely available, non-endangered primate species that is susceptible to GBV-B infection and develops a characteristic acute hepatitis. Here, animals were found to be susceptible to serially passaged serum and GBV-B transcripts. Hepatic pathology and peripheral viraemia could be quantified biochemically, immunophenotypically and morphologically, and persisted for periods of up to 6 months in some animals. Hepatitis was characterized by a marked influx of CD3+ CD8+ T lymphocytes and CD20+ B cells within the first 2 months of primary infection. The results of this study document the marmoset as another small, non-human primate species in which the pathogenesis of GBV-B can be studied and used as a surrogate model of HCV infection for investigation of pathogenesis and antiviral drug development.

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