Complement dependent cytotoxic antibody activity against measles virus in multiple sclerosis

1977 ◽  
Vol 216 (1) ◽  
pp. 39-46 ◽  
Author(s):  
V. Kratzsch ◽  
W. R. Kiessling ◽  
J. Wikstr�m ◽  
D. W. Meyer ◽  
K. Eickhoff ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Measles Virus ◽  
Antibody Activity ◽  
Cytotoxic Antibody

Measles virus polypeptide-specific antibody profile in multiple sclerosis

Neurology ◽  
1990 ◽  
Vol 40 (3, Part 1) ◽  
pp. 430-430 ◽  
Author(s):  
S. Dhib-Jalbut ◽  
K. Lewis ◽  
E. Bradburn ◽  
D. E. McFarlin ◽  
H. F. McFarland
Keyword(s):  
Multiple Sclerosis ◽  
Specific Antibody ◽  
Measles Virus ◽  
Antibody Profile

Failure to Detect Measles Virus Rna, by Reverse Transcription-Polymerase Chain Reaction, in Peripheral Blood Leucocytes of Patients with Multiple Sclerosis

1996 ◽  
Vol 1 (4) ◽  
pp. 204-206 ◽  
Author(s):  
B. Brankin ◽  
M. Osman ◽  
L. Herlihy ◽  
S.A. Hawkins ◽  
S.L. Cosby
Keyword(s):  
Multiple Sclerosis ◽  
Polymerase Chain Reaction ◽  
Reverse Transcription ◽  
Peripheral Blood ◽  
Measles Virus ◽  
Chain Reaction ◽  
Specific Primers ◽  
Polymerase Chain ◽  
Multiple Sclerosis Patients ◽  
Peripheral Blood Leucocytes

We have examined peripheral blood leucocytes (PBLs) from 17 multiple sclerosis patients, two patients with rheumatoid arthritis, one case of acute childhood measles and one case of subacute sclerosing panencephalitis, as well as 19 healthy adult controls for measles virus (MV) RNA, by the technique of reverse transcription-polymerase chain reaction. MV nucleocapsid gene specific primers were used to amplify all PBL-derived cDNA samples. These proved to be negative with the exception of the sample derived from the acute measles case. Selected cases were examined further, using fusion gene and matrix gene specific primers. MV RNA could not be detected.

Antibodies to Myelin Basic Protein and Measles Virus in Multiple Sclerosis: Precursor Frequency Analysis of the Antibody Producing B Cells

Autoimmunity ◽  
1991 ◽  
Vol 11 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Zhang Jingwu ◽  
Ying Chin ◽  
Paula Henderikx ◽  
Robert Medaer ◽  
C-H. Chou ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
B Cells ◽  
Myelin Basic Protein ◽  
Frequency Analysis ◽  
Measles Virus ◽  
Basic Protein ◽  
Precursor Frequency

Immunological Response against Allogeneic Chondrocytes Transplanted into Joint Surface Defects in Rats

1997 ◽  
Vol 6 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Anna Hyc ◽  
Jacek Malejczyk ◽  
Anna Osiecka ◽  
Stanislaw Moskalewski
Keyword(s):  
Mononuclear Cells ◽  
Surface Defects ◽  
Immunological Response ◽  
Joint Surface ◽  
Antibody Activity ◽  
Cytotoxic Antibody ◽  
Bone Transplants ◽  
Infiltrating Cells ◽  
Stimulation Of ◽  
Intact Rats

Rat chondrocytes isolated from the articular–epiphyseal cartilage complex were transplanted into defects prepared in articular cartilage and subchondral bone. Transplants were taken for examination after 3 and 8 wk. Cartilage formed by syngeneic chondrocytes did not evoke formation of infiltrations. Contrary to that, in the vicinity of cartilage produced by allogeneic chondrocytes numerous infiltrating cells were present and cartilage resorption could be observed. Cyclosporine-A (CsA) treatment of recipients of allogeneic chondrocytes only partially suppressed accumulation of infiltrating cells and matrix resorption. Antichondrocyte immune response of chondrocyte graft recipients was studied by evaluation of spleen mononuclear cells (SMC) stimulation in mixed splenocytechondrocyte cultures and by evaluation of antichondrocyte cytotoxic antibodies. No difference in stimulation of SMC from intact rats by syngeneic and allogeneic chondrocytes was observed. Stimulation by allogeneic chondrocytes was slightly but significantly higher in recipients of syngeneic grafts. SMC of allogenic chondrocyte recipients were strongly stimulated by allogeneic chondrocytes. This response was absent in recipients treated with CsA. Spontaneous antichondrocyte cytotoxic antibody activity was detected in intact rats and in recipients of syngeneic grafts. In recipients of allogeneic chondrocytes the antibody response against allogeneic chondrocytes was raised but was statistically not significant owing to the considerable variation in the level of spontaneously occurring antichondrocyte antibodies.

Intra-blood-brain barrier measles virus antibody synthesis in multiple sclerosis patients

Neurology ◽  
1983 ◽  
Vol 33 (1) ◽  
pp. 45-45 ◽  
Author(s):  
P. Albrecht ◽  
W. W. Tourtellotte ◽  
J. T. Hicks ◽  
H. Sato ◽  
E. J. Boone ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Blood Brain Barrier ◽  
Measles Virus ◽  
Brain Barrier ◽  
Virus Antibody ◽  
Antibody Synthesis ◽  
Blood Brain ◽  
Multiple Sclerosis Patients

Measles virus infection and multiple sclerosis

1976 ◽  
Vol 213 (4) ◽  
pp. 369-376 ◽  
Author(s):  
W. Cendrowski ◽  
I. Polna ◽  
K. Nowicka
Keyword(s):  
Multiple Sclerosis ◽  
Virus Infection ◽  
Measles Virus
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