Sex differences in locomotor activity and RNA synthesis in the central nervous system of Acheta domesticus L. during the circadian rhythm

1970 ◽  
Vol 70 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Bronislaw Cymborowski ◽  
Andrzej Dutkowski
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sex Differences ◽  
Circadian Rhythm ◽  
Locomotor Activity ◽  
Rna Synthesis ◽  
Acheta Domesticus ◽  
The Central Nervous System

Photic sensitivity of the rhinophore in Aplysia

1979 ◽  
Vol 57 (3) ◽  
pp. 698-701 ◽  
Author(s):  
Ronald Chase
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Circadian Rhythm ◽  
Locomotor Activity ◽  
Peripheral Nerve ◽  
Aplysia Californica ◽  
Optic Nerves ◽  
Peripheral Location ◽  
The Central Nervous System

A response to the onset of light was recorded electrophysiologically from the rhinophore nerve of Aplysia californica. Except for the optic nerves, no other peripheral nerve is known to carry photic information to the central nervous system. The result suggests a peripheral location for the extraocular photoreceptors which are known to be capable of controlling the circadian rhythm of locomotor activity.

Dissociation of circadian rhythms in rats with a hypothalamic island

1984 ◽  
Vol 246 (6) ◽  
pp. R949-R954
Author(s):  
S. Honma ◽  
K. Honma ◽  
T. Hiroshige
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Circadian Rhythm ◽  
Locomotor Activity ◽  
Corticosterone Level ◽  
Direct Consequence ◽  
Plasma Corticosterone ◽  
Spontaneous Locomotor Activity ◽  
Medial Basal Hypothalamus ◽  
The Central Nervous System

Complete isolation of the medial basal hypothalamus, including the suprachiasmatic nuclei in the isolated island, from the rest of the central nervous system was performed in rats. The circadian rhythm of plasma corticosterone level remained essentially intact in 5 of 16 rats with complete islands, whereas that of spontaneous locomotor activity was decomposed into ultradian bursts in 15 rats, resulting in a clear dissociation of the two rhythms in four rats. One rat, whose circadian rhythm of both variables persisted after the hypothalamic isolation, showed a diurnal activity. The 24-h patterns of plasma corticosterone of the other rats could be characterized as either episodic or continuously low throughout the day. A prefeeding corticosterone peak was detected under restricted feeding in rats with episodic fluctuations but not in those with continuously low hormone levels. It is concluded that the hypothalamic island includes the fundamental structures necessary for the manifestation of the entrained circadian rhythm of plasma corticosterone in rats under ad libitum feeding, whereas it contains only a part of that for spontaneous locomotor activity. The coupling pathways from the circadian oscillator(s) to these overt rhythms seem to be separate in the central nervous system, and the circadian rhythm of plasma corticosterone is not a direct consequence of that of locomotor activity.

Sex differences in the central nervous system

Endeavour ◽  
1987 ◽  
Vol 11 (3) ◽  
pp. 156-159 ◽  
Author(s):  
J.J. van der Werff ten Bosch ◽  
P. van der Schoot
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sex Differences ◽  
The Central Nervous System

The 13th J. A. F. Stevenson Memorial Lecture Sexual differentiation of the brain: possible mechanisms and implications

1985 ◽  
Vol 63 (6) ◽  
pp. 577-594 ◽  
Author(s):  
Roger A. Gorski
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sex Differences ◽  
Sexual Differentiation ◽  
Gonadal Hormones ◽  
Model Systems ◽  
Memorial Lecture ◽  
Actual Structure ◽  
The Central Nervous System ◽  
The Brain

The mammalian brain appears to be inherently feminine and the action of testicular hormones during development is necessary for the differentiation of the masculine brain both in terms of functional potential and actual structure. Experimental evidence for this statement is reviewed in this discussion. Recent discoveries of marked structural sex differences in the central nervous system, such as the sexually dimorphic nucleus of the preoptic area in the rat, offer model systems to investigate potential mechanisms by which gonadal hormones permanently modify neuronal differentiation. Although effects of these steroids on neurogenesis and neuronal migration and specification have not been conclusively eliminated, it is currently believed, but not proven, that the principle mechanism of steroid action is to maintain neuronal survival during a period of neuronal death. The structural models of the sexual differentiation of the central nervous system also provide the opportunity to identify sex differences in neurochemical distribution. Two examples in the rat brain are presented: the distribution of serotonin-immunoreactive fibers in the medial preoptic nucleus and of tyrosine hydroxylase-immunoreactive fibers and cells in the anteroventral periventricular nucleus. It is likely that sexual dimorphisms will be found to be characteristic of many neural and neurochemical systems. The final section of this review raises the possibility that the brain of the adult may, in response to steroid action, be morphologically plastic, and considers briefly the likelihood that the brain of the human species is also influenced during development by the hormonal environment.

The effect of Qing Huan Ling combined risperidone on the open field behavior of schizophrenic mice model

2016 ◽  
Vol 33 (S1) ◽  
pp. s289-s289
Author(s):  
Y. Zhang ◽  
F. Liu ◽  
Z. Dai ◽  
B. Wu ◽  
Q. Wu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Locomotor Activity ◽  
Open Field ◽  
Open Field Test ◽  
Model Group ◽  
Mice Model ◽  
Blank Group ◽  
The Central Nervous System ◽  
Risperidone Group

ObjectiveTo observe the effect of Qing Huan Ling and (or) risperidone on locomotor activity and explorative behavior of schizophrenia mice model by open field test.MethodsSeventy kunming mice were randomly divided into 5 groups, one group as blank group. The rest groups ip MK-801 continuously 14 day, then randomly numbered: model group, risperidone group, Qing Huan Ling group and risperidone combined Qing Huan Ling group. Ig give corresponding drugs for each group 4 weeks, observe the change of locomotor activity and explorative behavior by open field test.ResultsAfter Ig 4 weeks, compared with the blank group, there were no obvious difference in locomotor activity and explorative behavior between risperidone group, Qing Huan Ling group and the combined group. Compared with the model group, risperidone had statistics meaning in the repression of explorative behavior (P < 0.05),the combined group has statistics meaning in the repression of locomotor activity and explorative behavior (78.92 ± 36.18 m vs. 186.92 ± 41.08 m, P < 0.01).ConclusionQing Huan Ling regulate the central nervous system of schizophrenia mice model; when combined with risperidone, it restrain the central nervous system of schizophrenia mice model and the effect is stronger than risperidone alone.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Accuracy of Force Repeatability in Relation to its Value and the Subjects’ Sex

2017 ◽  
Vol 18 (2) ◽  
Author(s):  
Ryszard Błacha ◽  
Agnieszka D. Jastrzębska
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sex Differences ◽  
Muscle Force ◽  
Force Generation ◽  
Male Students ◽  
Minor Influence ◽  
The Central Nervous System ◽  
A Minor ◽  
Voluntary Contractions

AbstractThe purpose of the study was to determine the influence of force value and sex on force generation repeatability.The total of 17 female and 24 male students performed 3 maximal voluntary contractions for maximal force (FThe force generation repeatability rose with the increase of triggered force in both sexes; between force target 49 N vs. 98 N and 147 N (The influence of force value and a minor influence of sex on accuracy in generated forces might suggest that the control of muscle force by the central nervous system is similar in both sexes and the sex differences in muscle force generations are rather of muscle mass and structure.

THE INFLUENCE OF DIPHENYLHYDANTOIN AND CARBAMAZEPINE ON THE CIRCADIAN RHYTHM OF FREE URINARY CORTICOIDS AND ON THE SUPPRESSIBILITY OF THE BASAL AND THE "IMPULSIVE" ACTIVITY BY DEXAMETHASONE

1973 ◽  
Vol 72 (2) ◽  
pp. 308-318 ◽  
Author(s):  
J. Köbberling ◽  
A. v. zur Mühlen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Circadian Rhythm ◽  
Feedback Mechanism ◽  
Essential Condition ◽  
The Central Nervous System ◽  
Competitive Protein Binding ◽  
Pre Treatment ◽  
Higher Doses

ABSTRACT In eight normal volunteers the circadian rhythm of cortisol was established by the determination of free urinary corticoids in 2 h urine samples by the competitive protein binding method. After two control days dexamethasone was infused between 10 p. m. and 4 a. m. in doses between 50 and 400 μg/h. These experiments were repeated after pre-treatment with 400 mg diphenylhydantion/day for one week and again after pre-treatment with 800 mg carbamazepine/day. Under the influence of these anti-convulsant drugs the circadian rhythm of free urinary corticoids was still present but showed more irregularities and sometimes additional peaks in the course of the day. The 24 h excretion values, the peak and the nadir values and the time of the morning peaks were not significantly different from the control days. The degree of suppression by dexamethasone was dose related both with and without the application of the anti-convulsants but under the influence of both these drugs comparable effects could only be achieved by 2 to 4 fold higher doses of dexamethasone. The suppression of basal and impulsive cortisol activities was inhibited in a similar way. According to these results it can be assumed that the anti-convulsants interfere with the feedback mechanism by decreasing the sensitivity of the central nervous system to changes in plasma glucocorticoid concentrations. An intact feedback mechanism does not seem to be an essential condition for the circadian rhythm.

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