Cervical spine locking plate: in vitro biomechanical testing

1993 ◽  
Vol 1 (4) ◽  
pp. 222-225 ◽  
Author(s):  
Stephen A. Smith ◽  
Ronald W. Lindsey ◽  
Brian J. Doherty ◽  
Jerry W. Alexander ◽  
Jessie H. Dickson
1993 ◽  
Vol 7 (2) ◽  
pp. 171
Author(s):  
Stephen A. Smith ◽  
Ronald W. Lindsey ◽  
Brian J. Doherty ◽  
Jerry W. Alexander ◽  
Jessie H. Dickson

1992 ◽  
Vol 85 (Supplement) ◽  
pp. 3S-58
Author(s):  
S. A. Smith ◽  
R. W. Lindsey ◽  
B. J. Doherty ◽  
J. W. Alexander ◽  
J. H. Dickson

Author(s):  
Daniel M. Wido ◽  
Denis J. DiAngelo ◽  
Brian P. Kelly

A standard biomechanical testing protocol for evaluation of the sub-axial cervical spine is the application of pure bending moments to the free end of the spine (with opposing end fixed) and measurement of its motion response. The pure moment protocol is often used to compare spinal fusion instrumentation and has also been used to evaluate non-fusion instrumentation (e.g. disc arthroplasty devices) [1,2]. A variety of different testing systems have been employed to implement pure moment application. In cases where the loading is applied quasi-statically using a series of weights and pulleys the spine may relax between intermittent loading phases and/or unintended loading may be applied causing experimental artifact. Our objective was to use an existing programmable robotic testing platform (Spine Robot) to develop a novel real time force control strategy to simulate pure moment loading under precisely controlled continuous movement conditions. This would serve to advance robotic testing capabilities with an end goal to simulate different protocols in the same platform, and to potentially minimize fixturing and quasi-static artifacts.


Author(s):  
Richard A. Wawrose ◽  
Forbes E. Howington ◽  
Clarissa M. LeVasseur ◽  
Clair N. Smith ◽  
Brandon K. Couch ◽  
...  

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 733
Author(s):  
Milan Krticka ◽  
Ladislav Planka ◽  
Lucy Vojtova ◽  
Vladimir Nekuda ◽  
Premysl Stastny ◽  
...  

Many growth factors have been studied as additives accelerating lumbar fusion rates in different animal models. However, their low hydrolytic and thermal stability both in vitro and in vivo limits their workability and use. In the proposed work, a stabilized vasculogenic and prohealing fibroblast growth factor-2 (FGF2-STAB®) exhibiting a functional half-life in vitro at 37 °C more than 20 days was applied for lumbar fusion in combination with a bioresorbable scaffold on porcine models. An experimental animal study was designed to investigate the intervertebral fusion efficiency and safety of a bioresorbable ceramic/biopolymer hybrid implant enriched with FGF2-STAB® in comparison with a tricortical bone autograft used as a gold standard. Twenty-four experimental pigs underwent L2/3 discectomy with implantation of either the tricortical iliac crest bone autograft or the bioresorbable hybrid implant (BHI) followed by lateral intervertebral fixation. The quality of spinal fusion was assessed by micro-computed tomography (micro-CT), biomechanical testing, and histological examination at both 8 and 16 weeks after the surgery. While 8 weeks after implantation, micro-CT analysis demonstrated similar fusion quality in both groups, in contrast, spines with BHI involving inorganic hydroxyapatite and tricalcium phosphate along with organic collagen, oxidized cellulose, and FGF2- STAB® showed a significant increase in a fusion quality in comparison to the autograft group 16 weeks post-surgery (p = 0.023). Biomechanical testing revealed significantly higher stiffness of spines treated with the bioresorbable hybrid implant group compared to the autograft group (p < 0.05). Whilst histomorphological evaluation showed significant progression of new bone formation in the BHI group besides non-union and fibrocartilage tissue formed in the autograft group. Significant osteoinductive effects of BHI based on bioceramics, collagen, oxidized cellulose, and FGF2-STAB® could improve outcomes in spinal fusion surgery and bone tissue regeneration.


2013 ◽  
Vol 28 (8) ◽  
pp. 1264-1273 ◽  
Author(s):  
Andreas Weizbauer ◽  
Christian Modrejewski ◽  
Sabine Behrens ◽  
Helmut Klein ◽  
Patrick Helmecke ◽  
...  

Neurosurgery ◽  
1993 ◽  
Vol 32 (4) ◽  
pp. 682-683 ◽  
Author(s):  
H. Louis Harkey
Keyword(s):  

2002 ◽  
Vol 16 (2) ◽  
pp. 105-112 ◽  
Author(s):  
Hiroyuki Nakase ◽  
Yuki Ida ◽  
Rinsei Tei ◽  
Toshisuke Sakaki ◽  
Testuya Morimoto

2018 ◽  
Vol 7 (1) ◽  
pp. 111-120 ◽  
Author(s):  
A. MacLeod ◽  
A. H. R. W. Simpson ◽  
P. Pankaj

ObjectivesSecondary fracture healing is strongly influenced by the stiffness of the bone-fixator system. Biomechanical tests are extensively used to investigate stiffness and strength of fixation devices. The stiffness values reported in the literature for locked plating, however, vary by three orders of magnitude. The aim of this study was to examine the influence that the method of restraint and load application has on the stiffness produced, the strain distribution within the bone, and the stresses in the implant for locking plate constructs.MethodsSynthetic composite bones were used to evaluate experimentally the influence of four different methods of loading and restraining specimens, all used in recent previous studies. Two plate types and three screw arrangements were also evaluated for each loading scenario. Computational models were also developed and validated using the experimental tests.ResultsThe method of loading was found to affect the gap stiffness strongly (by up to six times) but also the magnitude of the plate stress and the location and magnitude of strains at the bone-screw interface.ConclusionsThis study demonstrates that the method of loading is responsible for much of the difference in reported stiffness values in the literature. It also shows that previous contradictory findings, such as the influence of working length and very large differences in failure loads, can be readily explained by the choice of loading condition. Cite this article: A. MacLeod, A. H. R. W. Simpson, P. Pankaj. Experimental and numerical investigation into the influence of loading conditions in biomechanical testing of locking plate fracture fixation devices. Bone Joint Res 2018;7:111–120. DOI: 10.1302/2046-3758.71.BJR-2017-0074.R2.


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