Single dose pharmacokinetics of proguanil and its metabolites in pregnancy

1993 ◽  
Vol 44 (3) ◽  
pp. 247-251 ◽  
Author(s):  
J. Wangboonskul ◽  
N. J. White ◽  
F. Nosten ◽  
F. ter Kuile ◽  
R. R. Moody ◽  
...  
Keyword(s):  
Single Dose ◽  
In Pregnancy

scholarly journals SINGLE DOSE SUXAMETHONIUM AND MUSCLE PAIN IN PREGNANCY

1983 ◽  
Vol 55 (8) ◽  
pp. 743-745 ◽  
Author(s):  
G.S. THIND ◽  
T.H.L. BRYSON
Keyword(s):  
Single Dose ◽  
Muscle Pain ◽  
In Pregnancy

Single Dose Suxamethonium and Muscle Pain in Pregnancy

1984 ◽  
Vol 4 (2) ◽  
pp. 53
Author(s):  
G. S. Thind ◽  
T. H. L. Bryson
Keyword(s):  
Single Dose ◽  
Muscle Pain ◽  
In Pregnancy

Recommended Treatment for Urinary Tract Infection in Pregnancy

1994 ◽  
Vol 28 (2) ◽  
pp. 248-251 ◽  
Author(s):  
Lavern M. Vercaigne ◽  
George G. Zhanel
Keyword(s):  
Urinary Tract Infection ◽  
Single Dose ◽  
Urinary Tract ◽  
Tract Infection ◽  
English Language ◽  
Data Extraction ◽  
Asymptomatic Bacteriuria ◽  
Recommended Treatment ◽  
Cure Rates ◽  
In Pregnancy

OBJECTIVE: To establish and recommend a therapeutic regimen for the treatment of urinary tract infection (UTI) in pregnancy based on the published studies. DATA SOURCES: An English-language literature search employing MEDLINE, Index Medicus, and bibliographic reviews of the references obtained were searched (key terms: urinary tract infection, UTI, pregnancy, bacteriuria). STUDY SELECTION AND DATA EXTRACTION: All identified human studies dealing with bacteriuria or UTI in pregnancy were analyzed. DATA SYNTHFSIS: Limited data are available regarding the appropriate antibiotic management of UTI in pregnancy. Single-dose cure rates with amoxicillin are approximately 80 percent. Trimethoprim/sulfamethoxazole provides cure rates of greater than 80 percent. Cephalosporins and nitrofurantoin produce variable results. CONCLUSIONS: We recommend separating pregnant subjects with UTI into two groups. Those with asymptomatic bacteriuria can be treated with a single dose of an antimicrobial to which the organism is susceptible. For those with symptomatic UTI, we recommend amoxicillin 500 mg tid for three days. Urine cultures should be repeated seven days following therapy to assess cure or failure. Well-designed studies need to be performed, comparing single-dose and three-day therapy for UTI in pregnancy.

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