A method of quantitative 67Ga scintigraphy in the evaluation of pulmonary sarcoidosis

1983 ◽  
Vol 8 (8) ◽  
pp. 351-353 ◽  
Author(s):  
J. G. van Unnik ◽  
E. A. van Roven ◽  
C. Alberts ◽  
J. B. van der Schoot
Keyword(s):  
Pulmonary Sarcoidosis ◽  
67Ga Scintigraphy

Efficacy of 67Ga-Scintigraphy in Predicting the Diagnostic Yield of Transbronchial Lung Biopsy in Pulmonary Sarcoidosis

CHEST Journal ◽  
1982 ◽  
Vol 82 (1) ◽  
pp. 7-9 ◽  
Author(s):  
Richard S. Ackart ◽  
Thomas L. Munzel ◽  
James J. Rodriguez ◽  
Charles J. Donlan ◽  
Ronald J. Klayton ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Diagnostic Yield ◽  
Pulmonary Sarcoidosis ◽  
Transbronchial Lung Biopsy ◽  
67Ga Scintigraphy

67Ga scintigraphy as an index of disease activity in pulmonary sarcoidosis

1981 ◽  
Vol 6 (5) ◽  
pp. 205-212 ◽  
Author(s):  
Chr. Alberts ◽  
J. B. van der Schoot ◽  
A. S. Groen
Keyword(s):  
Disease Activity ◽  
Pulmonary Sarcoidosis ◽  
67Ga Scintigraphy

Scintigraphy with 99m Tc-Phosphonate and 67Gallium in Patients Suspected of Primary Bone Tumors

1982 ◽  
Vol 21 (04) ◽  
pp. 136-139 ◽  
Author(s):  
C.-J. Edeling
Keyword(s):  
Soft Tissue ◽  
Bone Scintigraphy ◽  
Primary Tumor ◽  
Bone Tumors ◽  
Whole Body ◽  
Skeletal Metastases ◽  
Malignant Bone Tumors ◽  
67Ga Scintigraphy ◽  
Primary Bone Tumors ◽  
Primary Bone

Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the primary tumor in 43 cases, skeletal metastases in 6 cases and soft-tissue metastases in 8 cases. In 25 patients with secondary malignant bone tumors, bone scintigraphy visualized a single lesion in 10 cases and several lesions in 15 cases, and 67Ga scintigraphy detected the primary tumor in 17 cases, skeletal metastases in 17 cases and soft-tissue metastases in 9 cases. In 21 patients with benign bone disease positive uptake of 99mTc-phosphonate was recognized in 19 cases and uptake of 67Ga in 17 cases. It is concluded that bone scintigraphy should be used in patients suspected of primary bone tumors. If malignancy is suspected, 67Ga scintigraphy should be performed in addition.

Clinical features and outcome of acquired haemophilia A

2010 ◽  
Vol 30 (03) ◽  
pp. 156-161 ◽  
Author(s):  
R. Gheisari ◽  
B. Bomke ◽  
T. Hoffmann ◽  
R. E. Scharf
Keyword(s):  
Respiratory Diseases ◽  
Care Center ◽  
Treatment Algorithm ◽  
Early Death ◽  
Underlying Disease ◽  
Pulmonary Sarcoidosis ◽  
Relative Increase ◽  
Laboratory Evaluation ◽  
Haemophilia A ◽  
Acquired Haemophilia

SummaryWe have performed a monocenter study on 29 consecutive patients with acquired haemophilia A who were referred for diagnosis and treatment to the Düsseldorf Haemophilia Comprehensive Care Center between March 2001 and February 2010. Patients, methods: 18 men (age: 44–86 years) and 11 women (age: 20–83 years). For laboratory evaluation, a standardized staged protocol of aPTT, FVIII : C activity and concentration, mixing studies with patient and normal plasma, and quantification of inhibitor titers (Bethesda assay) was used. Diagnostic work-up included elaborate examinations for any underlying disease. Results: In 18 (62%) of the 29 patients with acquired haemophilia A, an underlying disorder was identified, including 9 patients with respiratory diseases (31%), 7 patients with autoimmune disorders (24%), one with malignancy, and one with postpartum state, while in 11 patients (38%) acquired haemophilia A remained idiopathic. Haemotherapy of bleeding, suppression or elimination of the inhibitor, and induction of immunotolerance to endogenous FVIII:C were performed according to a treatment algorithm. Predefined clinical endpoints were control of bleeding, eradication of the inhibitor, complete or partial remission (CR, PR), relapse, or early death (≤30 days). Of the 29 patients in total, 22 individuals achieved CR (76%), three had PR, one relapsed, and three died within 30 days (one of acute myocardial infarction while on anti-haemorrhagic treatment, one of sepsis while on immunosuppression due to active acquired haemophilia A, one of lung bleeding in association with pre-existing pulmonary sarcoidosis). Conclusion: This monocenter study demonstrates that control of life-threatening bleeding, eradication of the inhibitor, and induction of tolerance to endogenous FVIII have significantly improved the clinical outcome of acquired haemophilia A. Our data also suggest a shift in underlying disorders associated with acquired haemophilia A, whereby, in comparison to published studies, a relative increase in the proportion of patients with respiratory diseases is present.

67Ga Scintigraphy of the Brain - a Second Choice?

1974 ◽  
Vol 13 (02) ◽  
pp. 144-150
Author(s):  
C. - J. Edeling ◽  
O. Henriksen ◽  
J. Fogh
Keyword(s):  
Intracranial Tumours ◽  
67Ga Scintigraphy ◽  
The Brain

SummaryBrain scintigraphy with 99mmTc pertechnetate and subsequently with 6 7Ga citrate was carried out in 55 selected patients. Among 29 patients with normal 99mTc scintigrams, eleven suffered from intracranial tumours and in five of these, visualization of the tumour was obtained by means of 6 7Ga scintigraphy.Of 20 patients who showed abnormal 99mTc scintigrams as well as abnormal 6 7Ga scintigrams, eighteen suffered from intracranial tumours and two from infectious lesions of the brain.The remaining six patients who had abnormal 99mTc scintigrams but normal 6 7Ga scintigrams all suffered from vascular insults of the brain.It is concluded that 6 7Ga citrate often accumulates in tumours which are missed by 99mTc scintigraphy, and that 6 7Ga is not accumulated in areas of vascular insults of the brain as is 99mTc.

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