Measurement of cerebral blood flow in the pig by the 133Xe clearance technique

1981 ◽  
Vol 6 (10) ◽  
pp. 461-468 ◽  
Author(s):  
A. C. W. Volkers ◽  
W. A. van Duyl
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
133Xe Clearance ◽  
Clearance Technique

Cerebral blood flow during static exercise in humans

1990 ◽  
Vol 68 (6) ◽  
pp. 2358-2361 ◽  
Author(s):  
H. B. Rogers ◽  
T. Schroeder ◽  
N. H. Secher ◽  
J. H. Mitchell
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Venous Pressure ◽  
Voluntary Contraction ◽  
Knee Extensors ◽  
Flow Index ◽  
133Xe Clearance ◽  
Leg Exercise ◽  
Static Contractions ◽  
Clearance Technique

Cerebral blood flow (CBF) was determined in humans at rest and during four consecutive unilateral static contractions of the knee extensors. Each contraction was maintained for 3 min 15 s with the subjects in a semisupine position. The contractions corresponded to 8, 16, 24, and 32% of the maximal voluntary contraction (MVC) and utilized alternate legs. CBF (measured by the 133Xe clearance technique) was expressed by a noncompartmental flow index (ISI). Heart rate and mean arterial pressure increased from resting values of 73 (55-80) beats/min and 88 (74-104) mmHg to 106 (86-138) beats/min and 124 (102-146) mmHg, respectively (P less than 0.0005), during the contraction at 32% MVC. Arterial PCO2 and central venous pressure did not change. Corrected to the average resting PCO2, CBF during control was 55 (35-73) ml.100 g-1.min-1 and remained constant during contractions. Cerebral vascular resistance increased from 1.5 (1.0-2.2) to 2.4 (1.4-3.0) mmHg. 100 g.min.ml-1 (P less than 0.025) at 32% of MVC. There was no difference in CBF between the two hemispheres at rest or during exercise. In contrast to dynamic leg exercise, static leg exercise is not associated with an increase in global CBF when measured by the 133Xe clearance technique.

Effect of Pentoxifylline on Cerebral Blood Flow in Patients with Chronic Cerebrovascular Disease

1981 ◽  
Vol 9 (3) ◽  
pp. 211-214 ◽  
Author(s):  
Stefano Passero ◽  
Marcello Nardini ◽  
Noé Battistini
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cerebrovascular Disease ◽  
Pharmacological Treatment ◽  
Intravenous Infusion ◽  
Chronic Administration ◽  
Before And After ◽  
Clearance Technique

The effect of pentoxifylline on cerebral blood flow (CBF) was studied with the intravenous 133Xe clearance technique in eleven patients with chronic cerebrovascular disease. Pentoxifylline was administered orally at a dose of 1200 mg/day over a period of 30 days (eight patients) or by intravenous infusion of 100 ml saline containing 400 mg of the drug in 1 hour (three patients). CBF was measured before and after pharmacological treatment. CBF was found to be significantly increased by both acute and chronic administration of pentoxifylline.

scholarly journals 107. On the Clinical Application of Kr85 Clearance Technique to the Determination of Regional Cerebral Blood Flow

1965 ◽  
Vol 7 ◽  
pp. 244b-245
Author(s):  
Hajime NAGAI ◽  
Masahiro FURUSE ◽  
Kazuhiko OKAMURA ◽  
Inezo TODA ◽  
Yoshihiko OKA ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Clinical Application ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Clearance Technique
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