Nature of optokinetic response and zonal organization of climbing fiber afferents in the vestibulocerebellum of the pigmented rabbit

1990 ◽  
Vol 80 (2) ◽  
Author(s):  
M. Kusunoki ◽  
M. Kano ◽  
M.-S. Kano ◽  
K. Maekawa
Keyword(s):  
Climbing Fiber ◽  
Optokinetic Response ◽  
Zonal Organization

Zonal organization of climbing fiber projections to the uvula in the cat

1989 ◽  
Vol 279 (1) ◽  
pp. 138-148 ◽  
Author(s):  
Ken-Ichi Kanda ◽  
Yu Sato ◽  
Katsumi Ikarashi ◽  
Tadashi Kawasaki
Keyword(s):  
Climbing Fiber ◽  
Zonal Organization

Zonal organization of climbing fiber projections to the nodulus in the cat

1994 ◽  
Vol 638 (1-2) ◽  
pp. 1-11 ◽  
Author(s):  
Katsu-ichi Akaogi ◽  
Yu Sato ◽  
Katsumi Ikarashi ◽  
Tadashi Kawasaki
Keyword(s):  
Climbing Fiber ◽  
Zonal Organization

Spatiotemporal Tuning of Optic Flow Inputs to the Vestibulocerebellum in Pigeons: Differences Between Mossy and Climbing Fiber Pathways

2005 ◽  
Vol 93 (3) ◽  
pp. 1266-1277 ◽  
Author(s):  
Ian R. Winship ◽  
Peter L. Hurd ◽  
Douglas R. W. Wylie
Keyword(s):  
Optic Flow ◽  
Mossy Fiber ◽  
Temporal Frequency ◽  
Primary Response ◽  
Climbing Fiber ◽  
Accessory Optic System ◽  
Optokinetic Response ◽  
Preferred Direction ◽  
Spatiotemporal Tuning ◽  
P Cells

The pretectum, accessory optic system (AOS), and vestibulocerebellum (VbC) have been implicated in the analysis of optic flow and generation of the optokinetic response. Recently, using drifting sine-wave gratings as stimuli, it has been shown that pretectal and AOS neurons exhibit spatiotemporal tuning. In this respect, there are two groups: fast neurons, which prefer low spatial frequency (SF) and high temporal frequency (TF) gratings, and slow neurons, which prefer high SF–low TF gratings. In pigeons, there are two pathways from the pretectum and AOS to the VbC: a climbing fiber (CF) pathway to Purkinje cells (P cells) via the inferior olive and a direct mossy fiber (MF) pathway to the granular layer (GL). In the present study, we assessed spatiotemporal tuning in the VbC of ketamine-anesthetized pigeons using standard extracellular techniques. Recordings were made from 17 optic-flow-sensitive units in the GL, presumably granule cells or MF rosettes, and the complex spike activity (CSA) of 39 P-cells, which reflects CF input. Based on spatiotemporal tuning to gratings moving in the preferred direction, eight GL units were classified as fast units, with a primary response to low SF–high TF gratings (mean = 0.13 cpd/8.24 Hz), whereas nine were slow units preferring high SF–low TF gratings (mean = 0.68 cpd/0.30 Hz). CSA was almost exclusively tuned to slow gratings (mean = 0.67 cpd/0.35 Hz). We conclude that MF input to the VbC is from both fast and slow cells in the AOS and pretectum, whereas the CF input is primarily tuned to slow gratings.

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